Stroma-supported culture in childhood B-lineage acute lymphoblastic leukemia cells predicts treatment outcome.

Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples

1977 • 8,468 citations

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

Features of apoptotic cells measured by flow cytometry

1992 • 1,912 citations

Bcl-2 initiates a new category of oncogenes: regulators of cell death

1992 • 1,078 citations

Bcl-2 initiates a new category of oncogenes: regulators of cell death

1992 • 860 citations

Expression of Epstein–Barr Virus Transformation–Associated Genes in Tissues of Patients with EBV Lymphoproliferative Disease

1989 • 803 citations

Improved outcome in childhood acute lymphoblastic leukaemia with reinforced early treatment and rotational combination chemotherapy

1991 • 387 citations

Childhood Leukemias

1995 • 382 citations

Differentiation-Linked Leukemogenesis in Lymphocytes

1986 • 359 citations

Biology and clinical significance of cytogenetic abnormalities in childhood acute lymphoblastic leukemia

1990 • 354 citations

Biology and clinical significance of cytogenetic abnormalities in childhood acute lymphoblastic leukemia

1990 • 290 citations

Bone marrow-derived stromal cells prevent apoptotic cell death in B- lineage acute lymphoblastic leukemia

1992 • 265 citations

Ploidy of lymphoblasts is the strongest predictor of treatment outcome in B-progenitor cell acute lymphoblastic leukemia of childhood: a Pediatric Oncology Group study.

1992 • 248 citations

PITSLRE protein kinase activity is associated with apoptosis

1995 • 212 citations

Treatment of childhood acute lymphoblastic leukemia: results of Dana-Farber Cancer Institute/Children's Hospital Acute Lymphoblastic Leukemia Consortium Protocol 85-01.

1994 • 210 citations

The Molecular Basis of Leukemia

1994 • 210 citations

Prognostic implications of chromosomal findings in acute lymphoblastic leukaemia at diagnosis.

1978 • 195 citations

Adhesion-dependent survival of normal and leukemic human B lymphoblasts on bone marrow stromal cells

1994 • 160 citations

Ligation of CD38 suppresses human B lymphopoiesis.

1995 • 150 citations

Biology and treatment of acute lymphoblastic leukemia

1994 • 140 citations

Leukemic cell growth in SCID mice as a predictor of relapse in high- risk B-lineage acute lymphoblastic leukemia

1995 • 99 citations

Interleukin-4 induces programmed cell death (apoptosis) in cases of high-risk acute lymphoblastic leukemia

1994 • 79 citations

Monoclonal antibody-purified factor IX--comparative thrombogenicity to prothrombin complex concentrate.

1991 • 76 citations

Genetic instability in the development of drug resistance.

1985 • 70 citations

Stroma-supported immunocytometric assay (SIA): a novel method for testing the sensitivity of acute lymphoblastic leukemia cells to cytotoxic drugs.

1993 • 45 citations

Phenotypic and karyotypic properties of hyperdiploid acute lymphoblastic leukaemia of childhood

1985 • 38 citations

Use of stroma-supported cultures of leukemic cells to assess antileukemic drugs. I. Cytotoxicity of interferon alpha in acute lymphoblastic leukemia.

1993 • 33 citations

Bone marrow-derived stromal cells prevent apoptotic cell death in B- lineage acute lymphoblastic leukemia

1992 • 28 citations

A case of acute megakaryocytic leukemia with hematogones.

1993 • 20 citations

Use of stroma-supported cultures of leukemic cells to assess antileukemic drugs. II. Potent cytotoxicity of 2-chloro-deoxyadenosine in acute lymphoblastic leukemia.

1994 • 20 citations

Adhesion-dependent survival of normal and leukemic human B lymphoblasts on bone marrow stromal cells

1994 • 17 citations

Interleukin-4 induces programmed cell death (apoptosis) in cases of high-risk acute lymphoblastic leukemia

1994 • 10 citations