Induction of DNA Recombination by Activated 3‐Amino‐1‐methyl‐5H‐pyrido[4,3‐b]indole

A New Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia identified by Quinacrine Fluorescence and Giemsa Staining

1973 • 4,217 citations

Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma.

1986 • 1,118 citations

A general model for genetic recombination.

1975 • 890 citations

Mechanisms of bleomycin-induced DNA degradation

1987 • 869 citations

Oxidant-induced DNA damage of target cells.

1988 • 382 citations

Carcinogenicity of mutagenic heterocyclic amines formed during the cooking process

1985 • 373 citations

Gene losses in human tumours

1988 • 280 citations

Metabolic activation and covalent binding to nucleic acids of carcinogenic heterocyclic amines from cooked foods and amino acid pyrolysates.

1987 • 148 citations

Inhibitory effect of chlorophyll on the genotoxicity of 3-amino-1-methyl-5H-pyrido[4,3-b indole (Trp-P-2)

1989 • 119 citations

The human T cell receptor genes are targets for chromosomal abnormalities in T cell tumors

1989 • 109 citations

The SOS-function-inducing activity of chemical mutagens in Escherichia coli

1984 • 96 citations

Activation of a mutagen, 3-amino-1-methyl-5H-pyrido[4,3-b]indole. Identification of 3-hydroxyamino-1-methyl-5H-pyrido[4,3-b]indole and its reaction with DNA

1980 • 68 citations

Induction of sister-chromatid exchanges by mutagens from amino acid and protein pyrolysates

1980 • 62 citations

Activation and detoxication of N-hydroxy-Trp-P-2 by glutathione and glutathione transferases

1983 • 46 citations

DNA strand cleavage in vitro by 3-hydroxyamino-1-methyl-5H-pyrido[4,3-b]-indole, a direct-acting mutagen formed in the metabolism of carcinogenic 3-amino-1-methyl-5H-pyrido[4,3-b]indole.

1985 • 43 citations

Evidence for the involvement of N-hydroxylation of 3-amino-1-methyl-5H-pyrido[4,3-b]indole by cytochrome P-450 in the covalent binding to DNA.

1981 • 39 citations

Molecular Genetics of Human B Cell Neoplasia

1986 • 39 citations

Molecular Genetics of Human B-cell Neoplasia

1986 • 37 citations

Inhibitory activity of chlorophyllin on the genotoxicity of carcinogens in Drosophila

1994 • 34 citations

Effect of nucleotide excision repair in human cells on intrachromosomal homologous recombination induced by UV and 1-nitrosopyrene.

1990 • 24 citations

GENERATION OF INTRACELLULAR ACTIVE OXYGENS IN MOUSE FM3A CELLS BY 3‐HYDROXYAMINO‐1‐METHYL‐5H‐PYRIDO[4,3‐b]INDOLE, THE ACTIVATED TRP‐P‐2

1988 • 19 citations

Superoxide dismutase-mediated reversible conversion of 3-hydroxyamino-l-methyl-5H-pyrido(4,3-b) indole, the N-hydroxy derivative of Trp-P-2, into its nitroso derivative

1988 • 18 citations

Transformation depending on intermolecular homologous recombination is stimulated by UV damage in transfected DNA

1988 • 17 citations

Characterization of the effects of direct alkylators on in vitro immune responses

1990 • 13 citations

Homologous recombination of adenovirus DNA in mammalian cells: enhanced recombination following UV-irradiation of the virus

1992 • 12 citations

Translocation of chromosomes 16 and 18 in oxygen radical-transformed human lung fibroblasts

1990 • 8 citations

Effect of Nucleotide Excision Repair in Human Cells on Intrachromosomal Homologous Recombination Induced by UV and 1-Nitrosopyrene

1990 • 7 citations