DNA strand cleavage in vitro by 3-hydroxyamino-1-methyl-5H-pyrido[4,3-b]-indole, a direct-acting mutagen formed in the metabolism of carcinogenic 3-amino-1-methyl-5H-pyrido[4,3-b]indole.

A procedure for the isolation of deoxyribonucleic acid from micro-organisms

1961 • 11,554 citations

Dietary Carcinogens and Anticarcinogens

1983 • 3,028 citations

Prooxidant States and Tumor Promotion

1985 • 2,541 citations

REQUIREMENTS FOR TRANSFORMATION IN BACILLUS SUBTILIS

1961 • 2,206 citations

Fractionation of DNA from mammalian cells by alkaline elution

1976 • 838 citations

Spontaneous cancer and its possible relationship to oxygen metabolism.

1980 • 298 citations

DNA Strand Breakage in Human Leukocytes Exposed to a Tumor Promoter, Phorbol Myristate Acetate

1982 • 255 citations

Carcinogenicity in Mice of Mutagenic Compounds from a Tryptophan Pyrolyzate

1981 • 178 citations

Detection of potent mutagens, Trp-P-1 and Trp-P-2, in broiled fish

1980 • 109 citations

Identification of the breakage-reunion subunit of T4 DNA topoisomerase.

1984 • 88 citations

Induction of sister-chromatid exchanges by mutagens from amino acid and protein pyrolysates

1980 • 62 citations

Adenine phosphoribosyltransferase deficiency in cultured mouse mammary tumor FM3A cells resistant to 4-carbamoylimidazolium 5-olate.

1982 • 59 citations

In vitro transformation of hamster embryo cells with tryptophan pyrolysis products.

1977 • 44 citations

Syntheses of hydroxyamino, nitroso and nitro derivatives of Trp-P-2 and Glu-P-1, amino acid pyrolysate mutagens, and their direct mutagenicities towards Salmonella typhimurium TA98 and TA98NR

1983 • 42 citations

Evidence for the involvement of N-hydroxylation of 3-amino-1-methyl-5H-pyrido[4,3-b]indole by cytochrome P-450 in the covalent binding to DNA.

1981 • 39 citations

Species difference in N-hydroxylation of a tryptophan pyrolysis product in relation to mutagenic activation.

1981 • 38 citations

There is a correlation between the DNA affinity and mutagenicity of several 3-amino-1-methyl-5H-pyrido[4,3-b]indoles.

1980 • 31 citations

Concentration effect of bisulfite on the inactivation of transforming activity of DNA

1972 • 31 citations

Malignant transformation in vitro by tryptophan pyrolysis products.

1978 • 27 citations

The enhancing effect of cysteine and its derivatives on the mutagenic activities of the tryptophan-pyrolysis products, Trp-P-1 and Trp-P-2

1979 • 25 citations

Reparable lethal DNA damage produced by enzyme-activated 4-hydroxyaminoquinoline 1-oxide

1975 • 14 citations

Application of Bacillus subtilus spores in the detection of gas mutagens: A case of ethylene oxide

1979 • 12 citations

Action of exonuclease V (the recBC enzyme) on ultraviolet-irradiated DNA

1975 • 12 citations

Inactivation of transforming Bacillus subtilis deoxyribonucleic acid by monoadducts of 4,5',8-trimethylpsoralen

1981 • 6 citations

Inactivation of transforming DNA by a transient product of the interaction of Cu2+ and hydroquinone

1982 • 3 citations

Features of the damage produced by proflavine on transforming deoxyribonucleic acid

1979 • 2 citations