Deoletion of brain glutathione is accompanied by impaired micochondrial function and decreased N-acetyl aspartate concentration
Data up to Jan 2025
Total Citations Per Year
Abstract
References (46)
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
1951 • 319,299 citations
DETERMINATION OF SERUM PROTEINS BY MEANS OF THE BIURET REACTION
1949 • 16,078 citations
The Metabolic Basis of Inherited Disease
1990 • 4,327 citations
The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen
1973 • 2,608 citations
Mitochondrial Complex I Deficiency in Parkinson's Disease
1990 • 2,147 citations
Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains
1989 • 1,367 citations
[45] Cytochrome oxidase from beef heart mitochondria
1967 • 1,268 citations
The oxidative inactivation of mitochondrial electron transport chain components and ATPase.
1990 • 718 citations
Immunocytochemical localization of N-acetyl-aspartate with monoclonal antibodies
1991 • 625 citations
Rapid Communication: Oxidative Stress Induces Apoptosis in Embryonic Cortical Neurons
1994 • 588 citations
Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental lewy body disease
1992 • 533 citations
Specific Expression of N‐Acetylaspartate in Neurons, Oligodendrocyte‐Type‐2 Astrocyte Progenitors, and Immature Oligodendrocytes In Vitro
1992 • 504 citations
[2] Citrate synthase from rat liver
1969 • 435 citations
Glutathione deficiency leads to mitochondrial damage in brain.
1991 • 428 citations
Glutathione is present in high concentrations in cultured astrocytes but not in cultured neurons
1989 • 414 citations
N‐Acetyl‐Aspartyl‐Glutamate: Regional Levels in Rat Brain and the Effects of Brain Lesions as Determined by a New HPLC Method
1984 • 344 citations
Immunohistochemical localization of N-acetylaspartate in rat brain
1991 • 339 citations
[6] Preparation of synaptic and nonsynaptic mitochondria from mammalian brain
1979 • 294 citations
Synthesis of N-acetyl-<scp>l</scp>-aspartate by rat brain mitochondria and its involvement in mitochondrial/cytosolic carbon transport
1979 • 293 citations
STUDIES ON THE DISTRIBUTION OF N-ACETYL-l-ASPARTIC ACID IN BRAIN
1957 • 292 citations
High-affinity transport of glutathione is part of a multicomponent system essential for mitochondrial function.
1990 • 283 citations
New aspects of glutathione biochemistry and transport: selective alteration of glutathione metabolism.
1984 • 272 citations
Histochemical evaluation of glutathione in brain
1987 • 253 citations
Apoptosis and DNA degradation induced by 1-methyl-4-phenylpyridinium in neurons
1991 • 215 citations
Mitochondrial damage in muscle occurs after marked depletion of glutathione and is prevented by giving glutathione monoester.
1989 • 206 citations
Global ischaemia induces a biphasic response of the mitochondrial respiratory chain. Anoxic pre-perfusion protects against ischaemic damage
1992 • 141 citations
Abnormal hepatic mitochondrial respiration and cytochrome C oxidase activity in rats with long-term copper overload
1993 • 128 citations
Development of mitochondrial energy metabolism in rat brain
1977 • 127 citations
Near-Total Glutathione Depletion and Age-Specific Cataracts Induced by Buthionine Sulfoximine in Mice
1986 • 115 citations
Glutathione ester prevents buthionine sulfoximine-induced cataracts and lens epithelial cell damage.
1989 • 111 citations
Glutathione in Parkinson's disease: A link between oxidative stress and mitochondrial damage?
1992 • 108 citations
Myopathy in vitamin E deficient rats: muscle fibre necrosis associated with disturbances of mitochondrial function.
1993 • 95 citations
Iron induced oxidative stress and mitochondrial dysfunction: relevance to Parkinson's disease
1993 • 75 citations
Mitochondrial calcium handling and oxidative stress
1993 • 73 citations
Cytochrome c oxidase and cardiolipin alterations in response to skeletal muscle ischaemia and reperfusion
1990 • 71 citations
1H NMR study of cerebral development in the rat
1989 • 65 citations
Developmental Changes of N‐Acetyl‐L‐Aspartic Acid, N‐Acetyl‐α‐Aspartylglutamic Acid and β‐Citryl‐L‐Glutamic Acid in Different Brain Regions and Spinal Cords of Rat and Guinea Pig
1981 • 61 citations
Sequential damage in mitochondrial complexes by peroxidative stress
1991 • 57 citations
Lipid hydroperoxide induced mitochondrial dysfunction following acute ethanol intoxication in rats
1994 • 57 citations
Methods for depleting brain glutathione
1989 • 41 citations
Depletion of Brain Glutathione in Preweanling Mice by L‐Buthionine Sulfoximine
1988 • 35 citations
Cyclosporin A blocks 6-hydroxydopamine-induced efflux of Ca2+ from mitochondria without inactivating the mitochondrial inner-membrane pore
1994 • 29 citations
Induction of rat UDP-glucuronosyltransferase and glutathione S-transferase activities by L-buthionine-S,R-sulfoximine without induction of cytochrome P-450
1990 • 19 citations
Determination of cadaverine in active and dormant snails (Helix pomatia)
1974 • 15 citations
Mitochondria: A Practical Approach
1988 • 7 citations
Experimental Manipulation of Mitochondrial Glutathione Concentrations
1993 • 2 citations