Expression of p53 and bcl-2 and response to preoperative chemotherapy and radiotherapy for locally advanced squamous cell carcinoma of the oesophagus.

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1972 • 15,349 citations

Participation of p53 protein in the cellular response to DNA damage.

1991 • 3,818 citations

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1993 • 2,969 citations

Mechanisms and Genes of Cellular Suicide

1995 • 2,514 citations

Apoptosis. Its significance in cancer and cancer Therapy

1994 • 2,148 citations

p53 Status and the Efficacy of Cancer Therapy in Vivo

1994 • 1,483 citations

Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line

1993 • 898 citations

High levels of p53 protein in UV-irradiated normal human skin.

1993 • 689 citations

The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice.

1994 • 564 citations

The 1993 Walter Hubert Lecture: the role of the p53 tumour-suppressor gene in tumorigenesis

1994 • 428 citations

Bcl-2 blocks p53-dependent apoptosis.

1994 • 371 citations

Cell cycle arrests and radiosensitivity of human tumor cell lines: dependence on wild-type p53 for radiosensitivity.

1994 • 333 citations

Mechanisms of Apoptosis: Integration of Genetic, Biochemical, and Cellular Indicators

1994 • 320 citations

Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines.

1993 • 309 citations

Accumulation of p53 protein in human esophageal precancerous lesions: a possible early biomarker for carcinogenesis.

1993 • 194 citations

Archival analysis of p53 genetic and protein alterations in Chinese esophageal cancer.

1991 • 185 citations

Loss of 17p, mutation of the p53 gene, and overexpression of p53 protein in esophageal squamous cell carcinomas.

1993 • 145 citations

P53 protein expression and prognosis in squamous cell carcinoma of the esophagus

1994 • 134 citations

Bcl-2 Blocks p53-Dependent Apoptosis

1994 • 87 citations

Cancer Therapy Meets p53

1994 • 77 citations

p53 protein accumulation in oesophageal squamous cell carcinomas and precancerous lesions.

1995 • 15 citations