An endogenous activator of the Ca2+-dependent proteinase of human neutrophils that increases its affinity for Ca2+.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Fluorescamine: A Reagent for Assay of Amino Acids, Peptides, Proteins, and Primary Amines in the Picomole Range

1972 • 2,632 citations

A Neutral, Calcium-activated Proteinase from the Soluble Fraction of Rat Brain

1964 • 425 citations

Calcium‐dependent proteases: an enzyme system active at cellular membranes?

1987 • 308 citations

EXTRALYSOSOMAL PROTEIN DEGRADATION

1986 • 279 citations

The involvement of calpain in the activation of protein kinase C in neutrophils stimulated by phorbol myristic acid.

1986 • 228 citations

Studies of a Calcium-Activated Neutral Protease from Chicken Skeletal Muscle

1978 • 227 citations

Binding of protein kinase C to neutrophil membranes in the presence of Ca2+ and its activation by a Ca2+-requiring proteinase.

1985 • 193 citations

Endogenous inhibitor for calcium-dependent cysteine protease contains four internal repeats that could be responsible for its multiple reactive sites.

1987 • 164 citations

Evidence that treatment of platelets with phorbol ester causes proteolytic activation of Ca²⁺‐activated, phospholipid‐dependent protein kinase

1985 • 121 citations

Biochemical responses in activated human neutrophils mediated by protein kinase C and a Ca2+-requiring proteinase.

1986 • 114 citations

The Cytosol of Human Erythrocytes Contains a Highly Ca2+-Sensitive Thiol Protease (Calpain I) and Its Specific Inhibitor Protein (Calpastatin)1

1981 • 111 citations

Binding to erythrocyte membrane is the physiological mechanism for activation of Ca2+-dependent neutral proteinase

1985 • 70 citations

Phosphorylation and proteolytic modification of specific cytoskeletal proteins in human neutrophils stimulated by phorbol 12-myristate 13-acetate.

1987 • 63 citations

Purification and characterization of calcium-dependent proteases from rat heart.

1983 • 60 citations

Role of phospholipids in the activation of the Ca2+-dependent neutral proteinase of human erythrocytes

1985 • 60 citations

Following association to the membrane, human erythrocyte procalpain is converted and released as fully active calpain

1985 • 58 citations

Phosphorylation of proteins in human neutrophils activated with phorbol myristate acetate or with chemotactic factor

1986 • 52 citations

Purification and Characterization of an Inhibitor of Calcium- Activated Neutral Protease from Rabbit Skeletal Muscle

1981 • 47 citations

A calcium‐protease activator associated with brain microsomal‐insoluble elements

1986 • 46 citations

Phosphorylation by protein kinase C of a 20-kDa cytoskeletal polypeptide enhances its susceptibility to digestion by calpain.

1987 • 36 citations

Activation by hemoglobin of the Ca2+-requiring neutral proteinase of human erythrocytes: Structural requirements

1984 • 33 citations

Ca2+-dependent neutral proteinase from human erythrocytes: activation by Ca2+ ions and substrate and regulation by the endogenous inhibitor.

1984 • 28 citations

Reversible activation of human neutrophil calpain promoted by interaction with plasma membranes.

1985 • 21 citations

Two cytosolic, Ca2+-dependent, neutral proteinases from rabbit liver: Purification and properties of the proenzymes

1984 • 20 citations