Human neutrophils do not degrade major basement membrane components during chemotactic migration

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

Laminin–a glycoprotein from basement membranes.

1979 • 2,372 citations

HUMAN PLASMA PROTEINASE INHIBITORS

1983 • 2,129 citations

Leukocyte-endothelial interactions

1985 • 834 citations

Neutrophil activation on biological surfaces. Massive secretion of hydrogen peroxide in response to products of macrophages and lymphocytes.

1987 • 823 citations

Regulation of Rransendothelial Neutrophil Migration by Endogenous Interleukin-8

1991 • 813 citations

Leukocyte-endothelial interactions

1985 • 635 citations

A rapid and reproducible assay for collagenase using [1-14C]acetylated collagen

1979 • 350 citations

Regulation of Vascular Smooth Muscle Cell Migration and Proliferation In Vitro and in Injured Rat Arteries by a Synthetic Matrix Metalloproteinase Inhibitor

1996 • 311 citations

Neutrophils degrade subendothelial matrices in the presence of alpha-1-proteinase inhibitor. Cooperative use of lysosomal proteinases and oxygen metabolites.

1984 • 253 citations

Disruption of the subendothelial basement membrane during neutrophil diapedesis in an in vitro construct of a blood vessel wall.

1989 • 183 citations

Stimulus specificity of matrix metalloproteinase dependence of human T cell migration through a model basement membrane.

1996 • 173 citations

Regulation of Proteolysis at the Neutrophil-Substrate Interface by Secretory Leukoprotease Inhibitor

1990 • 168 citations

Adhesomes: specific granules containing receptors for laminin, C3bi/fibrinogen, fibronectin, and vitronectin in human polymorphonuclear leukocytes and monocytes.

1989 • 157 citations

Angiogenin promotes invasiveness of cultured endothelial cells by stimulation of cell-associated proteolytic activities.

1994 • 152 citations

Degradation of basement membrane laminin by human neutrophil elastase and cathepsin G.

1990 • 143 citations

Phagocytosing macrophages exclude proteins from the zones of contact with opsonized targets

1984 • 134 citations

Stimulation of matrix metalloproteinase‐dependent migration of T cells by eicosanoids

1995 • 128 citations

Elastase-mediated fibrinogenolysis by chemoattractant-stimulated neutrophils occurs in the presence of physiologic concentrations of antiproteinases.

1987 • 123 citations

Migration of neutrophils across monolayers of cultured microvascular endothelial cells An in vitro model of leucocyte extravasation

1987 • 121 citations

The Degradation of Human Glomerular Basement Membrane with Purified Lysosomal Proteinases: Evidence for the Pathogenic Role of the Polymorphonuclear Leucocyte in Glomerulonephritis

1978 • 115 citations

Targeted disruption of the tissue inhibitor of metalloproteinases gene increases the invasive behavior of primitive mesenchymal cells derived from embryonic stem cells in vitro.

1992 • 109 citations

Selective immunoreactivities of kidney basement membranes to monoclonal antibodies against laminin: localization of the end of the long arm and the short arms to discrete microdomains.

1989 • 97 citations

Proteinuria and structural alterations in rat glomerular basement membranes induced by intravenously injected anti-laminin immunoglobulin G.

1982 • 95 citations

Inhibition of tumor cell invasion by a highly conserved peptide sequence from the matrix metalloproteinase enzyme prosegment.

1992 • 86 citations

Overexpression of urokinase receptor increases matrix invasion without altering cell migration in a human osteosarcoma cell line.

1993 • 82 citations

Degradation of native type IV procollagen by human neutrophil elastase. Implications for leukocyte-mediated degradation of basement membranes

1987 • 79 citations

Neutrophil migration across monolayers of resting or cytokine-activated endothelial cells. Role of intracellular calcium changes and fusion of specific granules with the plasma membrane.

1992 • 54 citations

Laminin cleavage by activated human neutrophils yields proteolytic fragments with selective migratory properties

1993 • 53 citations

Type 1 fimbriate Escherichia coli stimulates a unique pattern of degranulation by human polymorphonuclear leukocytes

1988 • 49 citations

Macrophages form circular zones of very close apposition to lgG‐Coated surfaces

1990 • 47 citations

Gelatinase Contributes to the Degradation of Glomerular Basement Membrane Collagen by Human Neutrophils

1988 • 35 citations

Isolation, characterization, and amino-terminal amino acid sequence analysis of human neutrophil elastase from normal donors

1985 • 29 citations

Glomerular mesangial cells in vitro synthesize an aggregating proteoglycan immunologically related to versican

1994 • 28 citations

Rat mesangial cells in vitro synthesize a spectrum of proteoglycan species including those of the basement membrane and interstitium

1995 • 27 citations

Extracellular Matrix Composition and Resilience: Two Parameters that Influence the in Vitro Migration and Morphology of Rat Inner Cell Mass-Derived Cells1

1993 • 26 citations

Lymphocyte development of adherence and motility in extracellular matrix during IL-2 stimulation.

1992 • 26 citations

Migration of polymorphonuclear leukocytes through human amnion membrane--a scanning electron microscopic study.

1992 • 21 citations

Cryopreserved Cytoplasts From Human Neutrophils Migrate Across Monolayers of Human Endothelial Cells in Response to a Chemoattractant Gradient

1991 • 14 citations

Loss and rearrangement of glomerular basement membrane laminin during acute nephrotoxic nephritis in the rat.

1990 • 11 citations