CD4⁺ T‐cell‐mediated cytotoxicity against staphylococcal enterotoxin B‐pulsed synovial cells

Apoptosis in the Pathogenesis and Treatment of Disease

1995 • 6,610 citations

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

1991 • 4,682 citations

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1991 • 2,815 citations

Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family

1993 • 2,546 citations

The Staphylococcal Enterotoxins and Their Relatives

1990 • 1,914 citations

Induction of Apoptosis by Apo-2 Ligand, a New Member of the Tumor Necrosis Factor Cytokine Family

1996 • 1,793 citations

Generalized lymphoproliferative disease in mice, caused by a point mutation in the fas ligand

1994 • 1,549 citations

A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor.

1989 • 1,436 citations

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells

1994 • 844 citations

Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity.

1993 • 801 citations

Expression of the Fas ligand in cells of T cell lineage.

1995 • 659 citations

Evidence for the Effects of a Superantigen in Rheumatoid Arthritis

1991 • 632 citations

Fas antigen is the major target molecule for CD4+ T cell-mediated cytotoxicity.

1994 • 386 citations

A polyadenylate binding protein localized to the granules of cytolytic lymphocytes induces DNA fragmentation in target cells

1991 • 381 citations

Apoptosis in rheumatoid arthritis synovium.

1995 • 378 citations

Fas-mediated cytotoxicity by freshly isolated natural killer cells.

1995 • 372 citations

Participation of target Fas protein in apoptosis pathway induced by CD4+ Th1 and CD8+ cytotoxic T cells.

1994 • 309 citations

Limited T-cell receptor beta-chain heterogeneity among interleukin 2 receptor-positive synovial T cells suggests a role for superantigen in rheumatoid arthritis.

1991 • 297 citations

Elevated interleukin-10 levels in patients with rheumatoid arthritis

1995 • 243 citations

Apoptosis and functional fas antigen in rheumatoid arthritis synoviocytes

1995 • 234 citations

Augmented interleukin‐1 production and hla–dr expression in the synovium of rheumatoid arthritis patients

1988 • 222 citations

A monoclonal antibody reactive with a 15-kDa cytoplasmic granule-associated protein defines a subpopulation of CD8+ T lymphocytes.

1990 • 218 citations

Three receptor-linked protein-tyrosine phosphatases are selectively expressed on central nervous system axons in the Drosophila embryo

1991 • 212 citations

Fas/APO-1/CD95 system as a mediator of granulosa cell apoptosis in ovarian follicle atresia.

1996 • 203 citations

Activated B cells express functional Fas ligand

1996 • 202 citations

Binary and ternary complexes between T-cell receptor, class II MHC and superantigen in vitro

1994 • 182 citations

IL-1 receptor antagonist protein production and gene expression in rheumatoid arthritis and osteoarthritis synovium.

1992 • 124 citations

T cell receptor V beta gene bias in rheumatoid arthritis.

1993 • 112 citations

CGG: an unassigned or nonsense codon in Mycoplasma capricolum.

1991 • 101 citations

Restricted heterogeneity of T cell receptor transcripts in rheumatoid synovium.

1992 • 98 citations

Direct binding of secreted T-cell receptor beta chain to superantigen associated with class II major histocompatibility complex protein.

1991 • 87 citations

Inhibitory effect of clarithromycin on costimulatory molecule expression and cytokine production by synovial fibroblast-like cells

1996 • 87 citations

Fas and Fas Ligand Interaction Is Necessary for Human Osteoblast Apoptosis

1997 • 83 citations

Biased T cell receptor V_α region repertoire in the synovial fluid of rheumatoid arthritis patients

1991 • 82 citations

Characterization of T‐Cell Receptor αβ Repertoire in Synovial Tissue from Different Temporal Phases of Rheumatoid Arthritis

1992 • 80 citations

Inhibition of fas antigen‐mediated apoptosis of rheumatoid synovial cells in vitro by transforming growth factor β1

1996 • 80 citations

On the Cross-Reactivity of Staphylococcal Enterotoxins A, B, and C

1978 • 43 citations

Novel mechanisms of selective apoptosis in synovial T cells of patients with rheumatoid arthritis.

1996 • 43 citations

Immune Responses to 6 and 30‐kDa Mycobacterial Antigens in Rheumatoid Patients, and Vβ Usage by Specific Synovial T‐Cell Lines and Fresh T Cells

1991 • 43 citations

Fas (CD95)/Fas ligand interactions regulate antigen‐specific, major histocompatibility complex‐restricted T/B cell proliferative responses

1996 • 41 citations

Phenotypic characterization of lymphocytes infiltrating synovial tissue from patients with rheumatoid arthritis: analysis of lymphocytes isolated from minced synovial tissue by dual immunofluorescent staining.

1990 • 36 citations

FAS Antigen Expression on Synovial Cells Was Down-Regulated by Interleukin 1β

1996 • 35 citations

Phenotypic characteristics of T cells interacted with synovial cells.

1991 • 21 citations

Increased levels of serum IgM antibody to staphylococcal enterotoxin B in patients with rheumatoid arthritis.

1995 • 20 citations

Synovial cells are potent antigen-presenting cells for superantigen, staphylococcal enterotoxin B (SEB)

1995 • 18 citations

Increase in adhesion molecules on CD4+ cells and CD4+ cell subsets in synovial fluid from patients with rheumatoid arthritis.

1994 • 8 citations

Staphylococcal enterotoxin B‐specific adhesion of murine splenic T cells to a human endothelial cell line

1996 • 8 citations