Reduction in opiate receptor reserve in morphine tolerant guinea pig ilea

Dynorphin Is a Specific Endogenous Ligand of the κ Opioid Receptor

1982 • 1,160 citations

Cellular site of opiate dependence

1980 • 201 citations

Narcotic Receptor Sites in Morphine-dependent Rats

1974 • 201 citations

Morphine‐tolerant longitudinal muscle strip from guinea‐pig ileum

1973 • 155 citations

Demonstration of a specific dynorphin receptor in guinea pig ileum myenteric plexus

1981 • 145 citations

Synthesis and pharmacologic characterization of an alkylating analog chlornaltrexamine, of naltrexone with ultralong-lasting narcotic antagonist properties

1979 • 105 citations

Irreversible inactivation of the opiate receptors in the neuroblastoma x glioma hybrid NG108-15 by chlornaltrexamine.

1981 • 39 citations

Pharmacological studies with an alkylating narcotic agonist, chloroxymorphamine, and antagonist, chlornaltrexamine.

1980 • 37 citations

OPIATE BINDING AND EFFECT IN ILEUM PREPARATIONS FROM NORMAL AND MORPHINE PRETREATED GUINEA‐PIGS

1977 • 20 citations