OPIATE BINDING AND EFFECT IN ILEUM PREPARATIONS FROM NORMAL AND MORPHINE PRETREATED GUINEA‐PIGS

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Opiates and endogenous opioid peptides

1977 • 1,282 citations

A MODIFICATION OF RECEPTOR THEORY

1956 • 1,126 citations

Dual regulation of adenylate cyclase accounts for narcotic dependence and tolerance.

1975 • 663 citations

THE ACTION OF MORPHINE AND RELATED SUBSTANCES ON CONTRACTION AND ON ACETYLCHOLINE OUTPUT OF COAXIALLY STIMULATED GUINEA-PIG ILEUM

1957 • 636 citations

THE ACTION OF MORPHINE AND RELATED SUBSTANCES ON CONTRACTION AND ON ACETYLCHOLINE OUTPUT OF COAXIALLY STIMULATED GUINEA‐PIG ILEUM

1997 • 632 citations

KINETIC PARAMETERS OF NARCOTIC AGONISTS AND ANTAGONISTS, WITH PARTICULAR REFERENCE TO N‐ALLYLNOROXYMORPHONE (NALOXONE)

1968 • 392 citations

Narcotic Receptor Sites in Morphine-dependent Rats

1974 • 201 citations

Receptor binding and pharmacological activity of opiates in the guinea-pig intestine.

1975 • 182 citations

Principles of Drug Action

1995 • 170 citations

Morphine‐tolerant longitudinal muscle strip from guinea‐pig ileum

1973 • 155 citations

152 Possible role of enzyme inhibition and repression in drug tolerance and addiction

1961 • 152 citations

Cross tolerance between morphine and methionine-enkephalin

1976 • 125 citations

THE EFFECT OF ANALGESIC DRUGS ON THE RELEASE OF ACETYLCHOLINE FROM ELECTRICALLY STIMULATED GUINEA‐PIG ILEUM

1966 • 120 citations

Aspects of opiate dependence in the myenteric plexus of the guinea-pig

1976 • 117 citations

AGONIST AND ANTAGONIST ACTIONS OF MORPHINELIKE DRUGS ON THE GUINEA‐PIG ISOLATED ILEUM

1966 • 109 citations

The increased efficacy of narcotic antagonists induced by various narcotic analgesics.

1974 • 105 citations

Tissue responses to addictive drugs

1977 • 78 citations

XIX. Enzyme expansion theory of drug tolerance and physical dependence.

1968 • 67 citations

Stereospecific Uptake of Narcotic Analgesics by a Subcellular Fraction of the Guinea-pig Ileum

1973 • 54 citations

THE OFFSET OF MORPHINE TOLERANCE IN RATS AND MICE

1975 • 45 citations

Alternations in the efficacy of naloxone induced by stress, cyclic adenosine monophosphate, and morphine tolerance

1976 • 34 citations

Mechanism of development of tolerance to injected morphine by guinea pig ileum

1975 • 26 citations

Studies on the narcotic receptor in the guinea-pig ileum.

1976 • 25 citations