Organogenic Role of B Lymphocytes in Mucosal Immunity

RAG-1-deficient mice have no mature B and T lymphocytes

1992 • 2,859 citations

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene

1991 • 1,783 citations

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

1993 • 1,719 citations

Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages

1992 • 1,116 citations

A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells.

1992 • 818 citations

A New Method Using Hexamethyldisilazane for Preparation of Soft Insect Tissues for Scanning Electron Microscopy

1983 • 737 citations

A Novel Mouse with B Cells but Lacking Serum Antibody Reveals an Antibody-independent Role for B Cells in Murine Lupus

1999 • 694 citations

Sequential Uptake of Horseradish Peroxidase by Lymphoid Follicle Epithelium of Peyer's Patches in the Normal Unobstructed Mouse Intestine: An Ultrastructural Study

1977 • 673 citations

Conversion by Peyer's Patch Lymphocytes of Human Enterocytes into M Cells that Transport Bacteria

1997 • 625 citations

Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal.

1993 • 622 citations

B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice.

1996 • 581 citations

Pinocytosis by epithelium associated with lymphoid follicles in the bursa of fabricius, appendix, and Peyer's patches. An electron microscopic study

1973 • 562 citations

Humoral immune responses in CD40 ligand-deficient mice.

1994 • 541 citations

T cell receptor δ gene mutant mice: Independent generation of αβ T cells and programmed rearrangements of γδ TCR genes

1993 • 528 citations

A crucial role for B cells in neuroinvasive scrapie

1997 • 503 citations

Immunoglobulin gene rearrangement in B cell deficient mice generated by targeted deletion of the J_H locus

1993 • 404 citations

A superantigen encoded in the open reading frame of the 3′ long terminal repeat of mouse mammary tumour virus

1991 • 394 citations

B Lymphocytes Induce the Formation of Follicular Dendritic Cell Clusters in a Lymphotoxin α–dependent Fashion

1998 • 296 citations

IL-7 receptor α+ CD3– cells in the embryonic intestine induces the organizing center of Peyer's patches

1999 • 289 citations

Modified Thiocarbohydrazide Procedure for Scanning Electron Microscopy: Routine use for Normal, Pathological, or Experimental Tissues

1975 • 273 citations

M cells as ports of entry for enteroinvasive pathogens: Mechanisms of interaction, consequences for the disease process

1999 • 263 citations

Induction of autoreactive B cells allows priming of autoreactive T cells.

1991 • 253 citations

Transgenic mouse mammary tumor virus superantigen expression prevents viral infection

1992 • 223 citations

Differential expression of lectin-binding sites defines mouse intestinal M-cells.

1993 • 219 citations

Three distinctive steps in Peyer's patch formation of murine embryo

1997 • 205 citations

Peyer’s patch organogenesis is intact yet formation of B lymphocyte follicles is defective in peripheral lymphoid organs of mice deficient for tumor necrosis factor and its 55-kDa receptor

1997 • 205 citations

Superantigens of Mouse Mammary Tumor Virus

1995 • 196 citations

Superantigen-induced immune stimulation amplifies mouse mammary tumor virus infection and allows virus transmission

1993 • 189 citations

Cytochemical analysis of alkaline phosphatase and esterase activities and of lectin‐binding and anionic sites in rat and mouse Peyer's patch M cells

1983 • 174 citations

Uptake and transport of intestinal macromolecules and microorganisms by M cells in Peyer's patches— a personal and historical perspective

1999 • 164 citations

Increase of tuberculous infection in the organs of B cell-deficient mice

1996 • 162 citations

The M Cell as a Portal of Entry to the Lung for the Bacterial Pathogen Mycobacterium tuberculosis

1999 • 139 citations

Cytokine regulation of secondary lymphoid organ development

1998 • 123 citations

Pneumocystis carinii Infection in Transgenic B Cell-Deficient Mice

1996 • 115 citations

B cells are essential for murine mammary tumor virus transmission, but not for presentation of endogenous superantigens.

1994 • 114 citations

The composition and function of M cell apical membranes: Implications for microbial pathogenesis

1999 • 111 citations

A novel role for B cells in early protective immunity to an intracellular pathogen, Francisella tularensis strain LVS.

1997 • 75 citations

Retroviral infection of neonatal Peyer's patch lymphocytes: the mouse mammary tumor virus model.

1994 • 68 citations

Generation of a tumorigenic milk-borne mouse mammary tumor virus by recombination between endogenous and exogenous viruses

1997 • 62 citations

Development of Peyer's patches, follicle-associated epithelium and M cell: Lessons from immunodeficient and knockout mice

1999 • 56 citations

The Role of B Cells in the Establishment of T Cell Response in Mice Infected with an Intracellular Bacteria, Listeria monocytogenes

1999 • 43 citations

Direct physical interaction involving CD40 ligand on T cells and CD40 on B cells is required to propagate MMTV

1995 • 36 citations

The Nasal-associated Lymphoid Tissue of Adult Mice Acts as an Entry Site for the Mouse Mammary Tumor Retrovirus

1997 • 23 citations

Characterization of Two Infectious Mouse Mammary Tumour Viruses: Superantigenicity and Tumorigenicity

1999 • 20 citations