Cysteine residues in the zinc finger and amino acids adjacent to the finger are necessary for DNA binding by the LAC9 regulatory protein of Kluyveromyces lactis.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

Supercoil Sequencing: A Fast and Simple Method for Sequencing Plasmid DNA

1985 • 2,505 citations

Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes.

1985 • 2,450 citations

PROTEIN-DNA RECOGNITION

1984 • 1,649 citations

Potential Metal-Binding Domains in Nucleic Acid Binding Proteins

1986 • 1,096 citations

Deletion analysis of GAL4 defines two transcriptional activating segments

1987 • 898 citations

The pIC plasmid and phage vectors with versatile cloning sites for recombinant selection by insertional inactivation

1984 • 718 citations

Separation of DNA Binding from the Transcription-Activating Function of a Eukaryotic Regulatory Protein

1986 • 626 citations

GCN4 protein, synthesize in vitro, binds HIS3 regulatory sequences: Implications for general control of amino acid biosynthetic genes in yeast

1985 • 496 citations

Oestradiol induction of a glucocorticoid-responsive gene by a chimaeric receptor

1987 • 434 citations

Xenopus transcription factor A requires zinc for binding to the 5 S RNA gene.

1983 • 356 citations

Metal-dependent folding of a single zinc finger from transcription factor IIIA.

1987 • 301 citations

Primary Structure of the Saccharomyces cerevisiae GAL4 Gene

1984 • 276 citations

Sequence homology of the yeast regulatory protein ADR1 with Xenopus transcription factor TFIIIA

1986 • 217 citations

Genetic evidence that zinc is an essential co-factor in the DNA binding domain of GAL4 protein

1987 • 169 citations

Analysis of theKluyveromyces lactispositive regulatory geneLAC9reveals functional homology to, but sequence divergence from, theSaccharomyces cerevisiae GALAgene

1986 • 158 citations

Primary structure of the Saccharomyces cerevisiae GAL4 gene.

1984 • 142 citations

Yeast regulatory gene PPR1

1984 • 141 citations

Characterization of a Positive Regulatory Gene, LAC9, That Controls Induction of the Lactose-Galactose Regulon of Kluyveromyces lactis: Structural and Functional Relationships to GAL4 of Saccharomyces cerevisiae

1987 • 128 citations

Two zinc fingers of a yeast regulatory protein shown by genetic evidence to be essential for its function

1987 • 128 citations

Mutations that inactivate a yeast transcriptional regulatory protein cluster in an evolutionarily conserved DNA binding domain.

1987 • 105 citations

Nucleotide sequence of the ARGRII regulatory gene and amino acid sequence homologies between ARGRII PPRI and GAL4 regulatory proteins

1986 • 100 citations

Protein-DNA Recognition

1984 • 73 citations

Characterization of a positive regulatory gene, LAC9, that controls induction of the lactose-galactose regulon of Kluyveromyces lactis: structural and functional relationships to GAL4 of Saccharomyces cerevisiae.

1987 • 70 citations

Structure of yeast regulatory geneLEU3and evidence thatLEU3itself is under general amino acid control

1987 • 67 citations

GAL4 of Saccharomyces cerevisiae activates the lactose-galactose regulon of Kluyveromyces lactis and creates a new phenotype: glucose repression of the regulon.

1987 • 52 citations

Genetic and biochemical characterization of the galactose gene cluster in Kluyveromyces lactis

1984 • 48 citations

Positive regulation of the beta-galactosidase gene from Kluyveromyces lactis is mediated by an upstream activation site that shows homology to the GAL upstream activation site of Saccharomyces cerevisiae.

1987 • 40 citations

Identification of Upstream Activator Sequences That Regulate Induction of the β-Galactosidase Gene in Kluyveromyces lactis

1987 • 34 citations

Cistron mapping of tobacco vein mottling virus

1986 • 32 citations

Deleted Work

1955 • 0 citations