Neuroprotection after Several Days of Mild, Drug-Induced Hypothermia

Small Differences in Intraischemic Brain Temperature Critically Determine the Extent of Ischemic Neuronal Injury

1987 • 1,821 citations

Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage

1988 • 1,745 citations

Calcium Fluxes, Calcium Antagonists, and Calcium-Related Pathology in Brain Ischemia, Hypoglycemia, and Spreading Depression: A Unifying Hypothesis

1989 • 1,237 citations

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a Neuroprotectant for Cerebral Ischemia

1990 • 1,125 citations

Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil

1987 • 647 citations

Hypothermia but not the N-methyl-D-aspartate antagonist, MK-801, attenuates neuronal damage in gerbils subjected to transient global ischemia

1990 • 589 citations

Delayed postischemic hypothermia: a six month survival study using behavioral and histological assessments of neuroprotection

1995 • 488 citations

Intraischemic but Not Postischemic Brain Hypothermia Protects Chronically following Global Forebrain Ischemia in Rats

1993 • 481 citations

Postischemic moderate hypothermia inhibits CA1 hippocampal ischemic neuronal injury

1989 • 461 citations

Delayed and prolonged post-ischemic hypothermia is neuroprotective in the gerbil

1994 • 418 citations

Postischemic Blockade of AMPA but Not NMDA Receptors Mitigates Neuronal Damage in the Rat Brain following Transient Severe Cerebral Ischemia

1992 • 315 citations

Blockade of the AMPA receptor prevents CA1 hippocampal injury following severe but transient forebrain ischemia in adult rats

1991 • 253 citations

MK-801 reduced cerebral ischemic injury by inducing hypothermia

1990 • 205 citations

The non-NMDA antagonists, NBQX and GYKI 52466, protect against cortical and striatal cell loss following transient global ischaemia in the rat

1992 • 201 citations

AMPA, but not NMDA, receptor antagonism is neuroprotective in gerbil global ischaemia, even when delayed 24 h

1993 • 192 citations

Treatment with an AMPA Antagonist 12 Hours following Severe Normothermic Forebrain Ischemia Prevents CA₁ Neuronal Injury

1993 • 148 citations

Antagonism of non-NMDA receptors augments the neuroprotective effect of NMDA receptor blockade in cortical cultures subjected to prolonged deprivation of oxygen and glucose

1991 • 110 citations

Protection against ischemic hippocampal CAI damage in the rat with a new non-NMDA antagonist, NBQX

1992 • 108 citations

Neuroprotective Effect of Hypothermia in Cortical Cultures Exposed to Oxygen‐Glucose Deprivation or Excitatory Amino Acids

1994 • 98 citations

Regulation of ischemic hippocampal damage in the gerbil: Adrenalectomy alters the rate of CA1 cell disappearance

1990 • 92 citations

AMPA antagonists: do they hold more promise for clinical stroke trials than NMDA antagonists?

1993 • 88 citations

Direct measurement of brain temperature during and after intraischemic hypothermia: correlation with behavioral, physiological, and histological endpoints

1994 • 81 citations

Pharmacology of cerebral ischemia

1992 • 78 citations

Hypothermia ameliorates neuronal survival when induced 2 hours after ischaemia in the rat

1992 • 69 citations

The Prognosis and Treatment of Headaches in Children – a Ten Year Follow-up

1995 • 62 citations

Lack of Protection by the N-Methyl-D-aspartate Receptor Blocker Dizocilpine (MK-801) after Transient Severe Cerebral Ischemia in the Rat

1991 • 55 citations

Over-additive protective effect of dizocilpine and NBQX against neuronal damage

1994 • 47 citations

Protection by Two Non-NMDA Antagonists, NBQX and GYKI 52466 Against Selective Cell Loss following Transient Global Ischaemia (4VO) in the Rat

1992 • 29 citations

Protective effect of hypothermia during ischemia in neural cell cultures

1993 • 21 citations