Endocrine cells in pancreatic islets of Langerhans are immunoreactive to antibody against guanine nucleotide-binding protein (Go) purified from rat brain

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

1981 • 14,396 citations

Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.

1984 • 1,300 citations

Islet-activating protein, pertussis toxin: a probe for functions of the inhibitory guanine nucleotide regulatory component of adenylate cyclase

1984 • 567 citations

Simultaneous inhibitions of inositol phospholipid breakdown, arachidonic acid release, and histamine secretion in mast cells by islet-activating protein, pertussis toxin. A possible involvement of the toxin-specific substrate in the Ca2+-mobilizing receptor-mediated biosignaling system.

1985 • 509 citations

ADP-ribosylation of the specific membrane protein by islet-activating protein, pertussis toxin, associated with inhibition of a chemotactic peptide-induced arachidonate release in neutrophils. A possible role of the toxin substrate in Ca2+-mobilizing biosignaling.

1984 • 389 citations

Activation of two signal-transduction systems in hepatocytes by glucagon

1986 • 383 citations

Neural crest origin of the endocrine polypeptide (APUD) cells of the gastrointestinal tract and pancreas

1971 • 361 citations

The Neural Crest and the Origin of the Insulin-Producing and Other Gastrointestinal Hormone-Producing Cells

1976 • 335 citations

Two guanine nucleotide-binding proteins in rat brain serving as the specific substrate of islet-activating protein, pertussis toxin. Interaction of the alpha-subunits with beta gamma-subunits in development of their biological activities.

1986 • 315 citations

Islet-activating protein. A modifier of receptor-mediated regulation of rat islet adenylate cyclase.

1981 • 257 citations

Receptor-mediated inhibition of adenylate cyclase and stimulation of arachidonic acid release in 3T3 fibroblasts. Selective susceptibility to islet-activating protein, pertussis toxin.

1985 • 245 citations

Mechanisms for inhibition of the catalytic activity of adenylate cyclase by the guanine nucleotide-binding proteins serving as the substrate of islet-activating protein, pertussis toxin.

1986 • 233 citations

Physical and immunological characterization of a guanine nucleotide-binding protein purified from bovine cerebral cortex.

1985 • 205 citations

A new GTP‐binding protein in brain tissues serving as the specific substrate of islet‐activating protein, pertussis toxin

1987 • 189 citations

Go, a guanine nucleotide-binding protein: immunohistochemical localization in rat brain resembles distribution of second messenger systems.

1986 • 169 citations

Slow interaction of islet-activating protein with pancreatic islets during primary culture to cause reversal of alpha-adrenergic inhibition of insulin secretion.

1980 • 143 citations

Effects of Ca²⁺ and a phorbol ester on insulin secretion from islets of langerhans permeabilised by high‐voltage discharge

1985 • 101 citations

The fine structure and innervation of the beta and delta cells in the islet of Langerhans of the cat

1967 • 85 citations

Receptor-regulated G proteins

1986 • 82 citations

What is the developmental fate of the neural crest cells which migrate into the pancreas in the avian embryo?

1977 • 78 citations

Gut and Pancreatic Amine Precursor Uptake and Decarboxylation Cells Are Not Neural Crest Derivatives

1983 • 47 citations

Islet cell precursors are neurones

1982 • 44 citations

<italic>In Vitro</italic> Effects of Islet-Activating Protein on Cultured Rat Pancreatic Islets. Enhancement of Insulin Secretion, Adenosine 3': 5'-Monophosphate Accumulation and <sub>45</sub>Ca Flux

1981 • 30 citations

Immunohistochemical localization of guanine nucleotide-binding protein in rat retina

1987 • 27 citations

Guanine nucleotide‐binding protein in sea urchin eggs serving as the specific substrate of islet‐activating protein, pertussis toxin

1986 • 27 citations

An experimental investigation into the possible origin of pancreatic islet cells from rhombencephalic neurectoderm

1979 • 25 citations