Platelet 3H-imipramine binding distinguishes depression from Alzheimer dementia

Diagnostic Criteria for Use in Psychiatric Research

1972 • 5,688 citations

The Biochemistry of Affective Disorders

1967 • 1,183 citations

INTENSIFICATION OF THE CENTRAL SEROTONINERGIC PROCESSES AS A POSSIBLE DETERMINANT OF THE THYMOLEPTIC EFFECT

1969 • 705 citations

Tritiated Imipramine Binding Sites Are Decreased in the Frontal Cortex of Suicides

1982 • 478 citations

Tritiated Imipramine Binding Sites Are Decreased in Platelets of Untreated Depressed Patients

1980 • 440 citations

5-Hydroxytryptamine in the Hind-Brain of Depressive Suicides

1967 • 424 citations

The Human Platelet

1977 • 392 citations

Depressed Patients Have Decreased Binding of Tritiated Imipramine to Platelet Serotonin 'Transporter'

1981 • 317 citations

Biochemistry and pharmacology of the basal ganglia

1965 • 293 citations

L-Tryptophan in Mania

1974 • 272 citations

Specific tricyclic antidepressant binding sites in rat brain

1979 • 266 citations

Demonstration of specific high affinity binding sites for [3H] imipramine in human brain

1980 • 258 citations

Decreased uptake of 5-hydroxytryptamine in blood platelets from depressed patients

1976 • 251 citations

Specific tricyclic antidepressant binding sites in rat brain characterised by high-affinity 3H-imipramine binding

1980 • 249 citations

Human platelets possess high-affinity binding sites for 3H-imipramine

1979 • 241 citations

Serotonin Uptake in Blood Platelets of Psychiatric Patients

1981 • 235 citations

Demonstration of specific “high affinity” binding sites for [3H] imipramine on human platelets

1980 • 198 citations

Specific 3H-imipramine binding in human platelets

1980 • 183 citations

Does high affinity [3H] imipramine binding label serotonin reuptake sites in brain and platelet?

1981 • 163 citations

5-HYDROXYTRYPTAMINE DEFICIENCY IN PHENYLKETONURIA

1957 • 157 citations

Localisation of Tricyclic Antidepressant Binding Sites on Serotonin Nerve Terminals

1981 • 151 citations

High-affinity binding of 3H-imipramine in brain and platelets and its relevance to the biochemistry of affective disorders

1981 • 145 citations

Decreased 3H-imipramine binding in depressed males and females.

1980 • 132 citations

High-affinity 3H-imipramine binding in rat cerebral cortex

1979 • 127 citations

Reduced uptake of serotonin but unchanged 3H-imipramine binding in the platelets from cirrhotic patients

1981 • 106 citations

Distribution of Specific High‐Affinity Binding Sites for [³H]Imipramine in Human Brain

1981 • 104 citations

Normalization of platelet [3H]imipramine binding in depressed patients during remission

1982 • 102 citations

Tryptamine, a Substrate for the Serotonin Transporter in Human Platelets, Modifies the Dissociation Kinetics of [³H]Imipramine Binding: Possible Allosteric Interaction

1985 • 65 citations

Substituted tetrahydro-β-carbolines are possible candidates as endogenous ligand of the [3H]Imipramine recognition site

1984 • 64 citations

Lack of association between [3H]imipramine binding sites and uptake of serotonin in control, depressed and schizophrenic patients

1983 • 62 citations

Imipramine treatment differentially affects platelet 3H-imipramine binding and serotonin uptake in depressed patients

1985 • 59 citations

Possible endocrine role of the pineal gland for 6-methoxytetrahydro-β-carboline, a putative endogenous neuromodulator of the [3H]imipramine recognition site

1984 • 57 citations

Inhibition of synaptosomal 5‐[³H]hydroxytryptamine uptake by endogenous factor(s) in human blood

1984 • 50 citations

Reduced Vmax of 3H-serotonin uptake but unchanged 3H-imipramine binding in the platelets of untreated hypertensive subjects

1984 • 48 citations

Differential binding of 3H-imipramine and 3H-mianserin in rat cerebral cortex

1981 • 44 citations

Demonstration of endogenous “imipramine like” material in rat brain

1985 • 44 citations

Increases in choline levels in rat brain elicited by meclofenoxate

1982 • 38 citations

Methodological Aspects of Studies on the 5‐HT Uptake Mechanism in Normal Platelets

1981 • 28 citations

The active uptake of serotonin by platelets of schizophrenic patients and their families: Possibility of a genetic marker

1982 • 24 citations

Age alters the observed response of imipramine binding sites to chronic antidepressant treatment in female rats

1984 • 13 citations