Caveolin-1 Knockout Mice Show an Impaired Angiogenic Response to Exogenous Stimuli

Angiogenesis in cancer and other diseases

2000 • 8,734 citations

Mechanisms of angiogenesis and arteriogenesis

2000 • 4,120 citations

Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis.

1995 • 3,139 citations

Requirement of Vascular Integrin α _v β ₃ for Angiogenesis

1994 • 3,016 citations

Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

1994 • 2,293 citations

Loss of Caveolae, Vascular Dysfunction, and Pulmonary Defects in Caveolin-1 Gene-Disrupted Mice

2001 • 1,517 citations

Definition of Two Angiogenic Pathways by Distinct α _v Integrins

1995 • 1,333 citations

Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells.

1997 • 1,162 citations

Caveolin-1 Null Mice Are Viable but Show Evidence of Hyperproliferative and Vascular Abnormalities

2001 • 1,144 citations

Molecular mechanisms of blood vessel growth

2001 • 999 citations

Caveolae: From Cell Biology to Animal Physiology

2002 • 977 citations

Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis.

1997 • 924 citations

Biological Roles of Fibroblast Growth Factor-2*

1997 • 892 citations

Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin.

1995 • 840 citations

A Requirement for Caveolin-1 and Associated Kinase Fyn in Integrin Signaling and Anchorage-Dependent Cell Growth

1998 • 720 citations

Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization

1998 • 683 citations

Vascular Endothelial Growth Factor Induces Endothelial Fenestrations In Vitro

1998 • 638 citations

Enhanced pathological angiogenesis in mice lacking β3 integrin or β3 and β5 integrins

2002 • 604 citations

Emerging Themes in Lipid Rafts and Caveolae

2001 • 567 citations

Reduction of caveolin and caveolae in oncogenically transformed cells.

1995 • 505 citations

Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade

1998 • 473 citations

Biological Roles of Fibroblast Growth Factor-2

1997 • 434 citations

A Role for Caveolin and the Urokinase Receptor in Integrin-mediated Adhesion and Signaling

1999 • 402 citations

Integrin and Growth Factor Receptor Crosstalk

2001 • 394 citations

Caveolin-2-Deficient Mice Show Evidence of Severe Pulmonary Dysfunction without Disruption of Caveolae

2002 • 318 citations

Microvascular Hyperpermeability in Caveolin-1 (−/−) Knock-out Mice

2002 • 311 citations

Histology : cell and tissue biology

1983 • 296 citations

Integrin-Specific Activation of Rac Controls Progression through the G1 Phase of the Cell Cycle

2001 • 283 citations

Cellular aspects of transcapillary exchange

1983 • 277 citations

Regulation of Vascular Endothelial Growth Factor Receptor-2 Activity by Caveolin-1 and Plasma Membrane Cholesterol

2003 • 275 citations

De novo adipogenesis in mice at the site of injection of basement membrane and basic fibroblast growth factor

1998 • 274 citations

Purification from a human hepatoma cell line of a basic fibroblast growth factor-like molecule that stimulates capillary endothelial cell plasminogen activator production, DNA synthesis, and migration.

1986 • 272 citations

The Vesiculo–Vacuolar Organelle (VVO): A New Endothelial Cell Permeability Organelle

2001 • 271 citations

Fibroblast growth factors are required for efficient tumor angiogenesis.

2000 • 229 citations

Urokinase receptor: a molecular organizer in cellular communication

2000 • 213 citations

Caveolin-deficient mice: insights into caveolar function human disease

2001 • 202 citations

Caveolin-deficient mice: insights into caveolar function human disease

2001 • 193 citations

Caveolin-1 Mutations (P132L and Null) and the Pathogenesis of Breast Cancer

2002 • 188 citations

Pathways of Macromolecular Extravasation Across Microvascular Endothelium in Response to VPF/VEGF and Other Vasoactive Mediators

1999 • 180 citations

Caveolin-1 Expression Enhances Endothelial Capillary Tubule Formation

2002 • 166 citations

Absence of Caveolin-1 Sensitizes Mouse Skin to Carcinogen-Induced Epidermal Hyperplasia and Tumor Formation

2003 • 160 citations

Loss of Caveolin-1 Gene Expression Accelerates the Development of Dysplastic Mammary Lesions in Tumor-Prone Transgenic Mice

2003 • 143 citations

The Cardiovascular System

1983 • 137 citations

Importance of Vascular Phenotype by Basic Fibroblast Growth Factor, and Influence of the Angiogenic Factors Basic Fibroblast Growth Factor/Fibroblast Growth Factor Receptor-1 and Ephrin-A1/EphA2 on Melanoma Progression

2002 • 135 citations

A peptide derived from the nonreceptor binding region of urokinase plasminogen activator (uPA) inhibits tumor progression and angiogenesis and induces tumor cell death in vivo

2000 • 127 citations

Caveolin-1-deficient Mice Show Accelerated Mammary Gland Development During Pregnancy, Premature Lactation, and Hyperactivation of the Jak-2/STAT5a Signaling Cascade

2002 • 110 citations

Caveolin-1 Expression Is Down-Regulated in Cells Transformed by the Human Papilloma Virus in a p53-Dependent Manner. Replacement of Caveolin-1 Expression Suppresses HPV-Mediated Cell Transformation

2000 • 94 citations

Knockdown of Caveolin-1 by Antisense Oligonucleotides Impairs Angiogenesis in Vitro and in Vivo

2000 • 87 citations

Decreased B16F10 melanoma growth and impaired vascularization in telomerase-deficient mice with critically short telomeres.

2002 • 85 citations

Caveolae and Vesiculo-Vacuolar Organelles in Bovine Capillary Endothelial Cells Cultured with VPF/VEGF on Floating Matrigel-collagen Gels

1999 • 78 citations

Purification from a Human Hepatoma Cell Line of a Basic Fibroblast Growth Factor-Like Molecule that Stimulates Capillary Endothelial Cell Plasminogen Activator Production, DNA Synthesis, and Migration

1986 • 55 citations

Transcriptional and posttranscriptional regulation of urokinase‐type plasminogen activator expression in endothelial cells by basic fibroblast growth factor

1995 • 48 citations

Integrin α_vβ₃ is involved in stimulated migration of vascular adventitial fibroblasts by basic fibroblast growth factor but not platelet‐derived growth factor

2001 • 23 citations