Acquisition of regulatory function by human CD8⁺ T cells treated with anti‐CD3 antibody requires TNF

TH-17 cells in the circle of immunity and autoimmunity

2007 • 1,520 citations

Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

2003 • 1,252 citations

Anti-CD3 Monoclonal Antibody in New-Onset Type 1 Diabetes Mellitus

2002 • 1,189 citations

Novel Inhibitors of Cytokine-induced IκBα Phosphorylation and Endothelial Cell Adhesion Molecule Expression Show Anti-inflammatory Effects in Vivo

1997 • 1,045 citations

Tolerization of dendritic cells by TS cells: the crucial role of inhibitory receptors ILT3 and ILT4

2002 • 800 citations

Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B.

1998 • 721 citations

A Single Course of Anti-CD3 Monoclonal Antibody hOKT3γ1(Ala-Ala) Results in Improvement in C-Peptide Responses and Clinical Parameters for at Least 2 Years after Onset of Type 1 Diabetes

2005 • 622 citations

TGF-β-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes

2003 • 595 citations

Interaction of TNF with TNF Receptor Type 2 Promotes Expansion and Function of Mouse CD4+CD25+ T Regulatory Cells

2007 • 509 citations

Suppressor cell activity after concanavalin A treatment of lymphocytes from normal donors.

1976 • 503 citations

Rituximab in relapsing‐remitting multiple sclerosis: A 72‐week, open‐label, phase I trial

2008 • 502 citations

Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cells

2004 • 482 citations

Regulatory T cells under scrutiny

2003 • 427 citations

Transplantation of Cultured Islets from Two-Layer Preserved Pancreases in Type 1 Diabetes with Anti-CD3 Antibody

2004 • 367 citations

TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs

2005 • 339 citations

Cutting Edge: Expression of TNFR2 Defines a Maximally Suppressive Subset of Mouse CD4+CD25+FoxP3+ T Regulatory Cells: Applicability to Tumor-Infiltrating T Regulatory Cells

2008 • 302 citations

MHC-Restricted Depletion of Human Myelin Basic Protein-Reactive T Cells by T Cell Vaccination

1993 • 286 citations

Suppression of NF-κB activity by sulfasalazine is mediated by direct inhibition of IκB kinases α and β

2000 • 285 citations

Intravenous Immunoglobulin Therapy Affects T Regulatory Cells by Increasing Their Suppressive Function

2007 • 226 citations

CD8+CD28− T Regulatory Lymphocytes Inhibiting T Cell Proliferative and Cytotoxic Functions Infiltrate Human Cancers

2007 • 222 citations

In Vitro Characterization of Five Humanized OKT3 Effector Function Variant Antibodies

2000 • 219 citations

A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin

2001 • 210 citations

Co‐expression of TNFR2 and CD25 identifies more of the functional CD4⁺FOXP3⁺ regulatory T cells in human peripheral blood

2010 • 193 citations

Identification of a human CD8⁺regulatory T cell subset that mediates suppression through the chemokine CC chemokine ligand 4

2007 • 184 citations

The Specific Regulation Of Immune Responses By CD8⁺T Cells Restricted By The MHC Class Ib Molecule, Qa-1

2000 • 168 citations

Membrane Tumor Necrosis Factor (TNF) Induces p100 Processing via TNF Receptor-2 (TNFR2)

2009 • 155 citations

Qa-1 restriction of CD8+ suppressor T cells

2004 • 142 citations

NFκB Activation Is Required for the Neuroprotective Effects of Pigment Epithelium-derived Factor (PEDF) on Cerebellar Granule Neurons

2001 • 135 citations

Rapamycin Monotherapy in Patients With Type 1 Diabetes Modifies CD4+CD25+FOXP3+ Regulatory T-Cells

2008 • 134 citations

Generation and function of antigen-specific suppressor and regulatory T cells

2003 • 111 citations

TNF-α: An Activator of CD4+FoxP3+TNFR2+ Regulatory T Cells

2010 • 106 citations

Anti tumour necrosis‐α therapy increases the number of FOXP3⁺ regulatory T cells in children affected by Crohn’s disease

2008 • 105 citations

Isolation and characterization of CD8+ regulatory T cells in multiple sclerosis

2008 • 94 citations

Concanavalin A-activated suppressor cells in normal human peripheral blood lymphocytes.

1976 • 90 citations

Unique Phenotype of Human Tonsillar and In Vitro-Induced FOXP3+CD8+ T Cells

2009 • 80 citations

Suppression of autoimmune disease after vaccination with autoreactive T cells that express Qa-1 peptide complexes

2004 • 76 citations

Human CD8+ T lymphocyte clones specific for T cell receptor Vβ families expressed on autologous CD4+ T cells

1995 • 69 citations

CD8+ regulatory T cells in persistent human viral infections

2008 • 37 citations

CD28/CD154 Blockade Prevents Autoimmune Diabetes by Inducing Nondeletional Tolerance After Effector T-Cell Inhibition and Regulatory T-Cell Expansion

2008 • 32 citations

Suppressor activity of the human spleen and thymus.

1976 • 31 citations

The role of cytokines (and not only) in inducing and expanding T regulatory type 1 cells.

2004 • 31 citations

Involvement of nuclear factor-kappa B (NF-κB) activation in mitogen-induced lymphocyte proliferation: inhibitory effects of lymphoproliferation by salicylates acting as NF-κB inhibitors22Abbreviations: ASA, acetylsalicylic acid; COX, cyclooxygenase; ERK, extracellular receptor-activated kinase; FBS, fetal bovine serum; IL-2, interleukin-2; JNK, c-Jun N-terminal kinase; MAP, mitogen-activated protein kinase; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NF-KB, nuclear factor…

2001 • 29 citations

Adeno-Associated Viral Vector-Mediated Interleukin-10 Prolongs Allograft Survival in a Rat Kidney Transplantation Model

2007 • 27 citations

Human Regulatory CD8⁺ T Cells

2008 • 24 citations

Dynamic Protein Complexes Regulate NF-κB Signaling

2008 • 22 citations

Treatment of type 1 diabetes with anti-CD3 monoclonal antibody.

2003 • 9 citations

In vivo T cell activation properties of anti-T cell monoclonal antibodies.

1993 • 6 citations