Regulation of inositol transport by glucose and protein kinase C in mesangial cells

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Structural-functional relationships in diabetic nephropathy.

1984 • 1,202 citations

Sorbitol, Phosphoinositides, and Sodium-Potassium-ATPase in the Pathogenesis of Diabetic Complications

1987 • 905 citations

Role of phosphoinositides in transmembrane signaling.

1990 • 491 citations

Physiology of the mesangial cell

1989 • 484 citations

Activation of protein kinase C by elevation of glucose concentration: proposal for a mechanism in the development of diabetic vascular complications.

1989 • 374 citations

Ganglioside inhibition of glutamate-mediated protein kinase C translocation in primary cultures of cerebellar neurons.

1987 • 309 citations

Metabolism and Function of myo-Inositol and Inositol Phospholipids

1986 • 298 citations

A synthetic peptide substrate for selective assay of protein kinase C

1990 • 292 citations

myo-INOSITOL AS AN ESSENTIAL GROWTH FACTOR FOR NORMAL AND MALIGNANT HUMAN CELLS IN TISSUE CULTURE

1957 • 268 citations

Regulation of Protein Kinase C by Nerve Growth Factor, Epidermal Growth Factor, and Phorbol Esters in PC12 Pheochromocytoma Cells

1989 • 219 citations

Stimulation of rat mesangial cell proliferation by macrophage interleukin 1.

1983 • 219 citations

Improved methods for culturing rat glomerular cells

1984 • 199 citations

Are Disturbances of Sorbitol, Phosphoinositide, and Na+-K+-ATPase Regulation Involved in Pathogenesis of Diabetic Neuropathy?

1988 • 183 citations

Glomerular Polyol Accumulation in Diabetes and its Prevention by Oral Sorbinil

1984 • 160 citations

Independent phosphatidylinositol synthesis in pituitary plasma membrane and endoplasmic reticulum

1987 • 132 citations

Osmoregulatory changes in myo-inositol transport by renal cells.

1989 • 132 citations

Myo-inositol and prostaglandins reverse the glucose inhibition of neural tube fusion in cultured mouse embryos

1990 • 113 citations

Inter-Relations between the Phospholipids of Rat Pancreatic Islets during Glucose Stimulation and Their Response to Medium Inositol and Tetracaine

1975 • 83 citations

Effects of hyperglycaemia on sorbitol and myo-inositol contents of cultured embryos: treatment with aldose reductase inhibitor and myo-inositol supplementation

1990 • 72 citations

Impaired contractile responsiveness of diabetic glomeruli to angiotensin II: A possible indication of mesangial dysfunction in diabetes mellitus

1986 • 68 citations

Glucose inhibits myo-inositol uptake and reduces myo-inositol content in cultured rat glomerular mesangial cells

1990 • 68 citations

Approaches to the Study of Protein Kinase C Involvement in Signal Transduction

1988 • 53 citations

Uptake of myo-Inositol by Early-Somite Rat Conceptus: Transport Kinetics and Effects of Hyperglycemia

1990 • 51 citations

myo‐Inositol Metabolism in 41 A3 Neuroblastoma Cells: Effects of High Glucose and Sorbitol Levels

1987 • 50 citations

Decreased Myo-Inositol Content and Na+-K+-ATPase Activity in Superior Cervical Ganglion of STZ-Diabetic Rat and Prevention by Aldose Reductase Inhibition

1986 • 42 citations

The polyol pathway, sorbinil, and renal dysfunction

1986 • 41 citations

Competitive inhibition by glucose of myo-inositol incorporation into cultured porcine aortic endothelial cells

1990 • 32 citations

Effect of Galactose and Glucose Levels and Sorbinil Treatment on myo-Inositol Metabolism and Na+-K+ Pump Activity in Cultured Neuroblastoma Cells

1989 • 27 citations

Effect of Sorbinil on myo‐Inositol Metabolism in Cultured Neuroblastoma Cells Exposed to Increased Glucose Levels

1988 • 25 citations

Chronic exposure to high glucose decreases myo-inositol in cultured cerebral microvascular pericytes but not in endothelium

1988 • 25 citations

Myo-inositol transport into endothelial cells derived from nervous system microvessels

1990 • 23 citations

Effects of glucose on receptor-mediated phosphoinositide hydrolysis and second messenger generation in rat glomerular mesangial cells.

1991 • 23 citations

Regulation of uptake of inositol by glucose in cultured retinal pigment epithelial cells

1988 • 21 citations

Abnormal metabolism of polyunsaturated fatty acids and phospholipids in diabetic glomeruli

1987 • 15 citations

Carrier-dependent and carrier-independent uptake of myo-inositol in cultured retinal pigment epithelial cells: activation by heat and concentration

1988 • 12 citations

Selective low level of protein kinase C isozyme in a tumor promoter-dependent mouse leukemia cell line

1989 • 5 citations