K-ras activation andras p21 expression in latent prostatic carcinoma in Japanese men

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

1981 • 14,396 citations

A genetic model for colorectal tumorigenesis

1990 • 11,800 citations

Genetic Alterations during Colorectal-Tumor Development

1988 • 6,691 citations

Prediction of Prognosis for Prostatic Adenocarcinoma by Combined Histological Grading and Clinical Staging

1974 • 2,200 citations

Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes

1988 • 2,121 citations

Prevalence of ras gene mutations in human colorectal cancers

1987 • 1,866 citations

Mechanism of activation of a human oncogene

1982 • 1,417 citations

A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

1982 • 1,398 citations

Cellular Oncogenes and Multistep Carcinogenesis

1983 • 1,154 citations

Detection of high incidence of K-ras oncogenes during human colon tumorigenesis

1987 • 1,074 citations

Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis

1986 • 865 citations

Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats

1985 • 829 citations

THE MOLECULAR GENETICS OF CELLULAR ONCOGENES

1984 • 765 citations

Detection of human papilloma virus in paraffin-embedded tissue using the polymerase chain reaction.

1988 • 748 citations

KRAS codon 12 mutations occur very frequently in pancreatic adenocarcinomas

1988 • 620 citations

Mutational Activation of the K-rasOncogene

1987 • 542 citations

Expression ofrasOncogene p21 in Prostate Cancer

1986 • 269 citations

v-ras genes from harvey and BALB murine sarcoma viruses can act as initiators of two-stage mouse skin carcinogenesis

1986 • 244 citations

Analysis of RAS oncogene mutations in human lymphoid malignancies.

1988 • 226 citations

Expression of p21ras in fresh primary and metastatic human colorectal tumors.

1985 • 181 citations

ras Oncogene p21 expression is increased in premalignant lesions and high grade bladder carcinoma.

1985 • 173 citations

Comparative Study of Latent Carcinoma of the Prostate Among Japanese in Japan and Hawaii 2

1973 • 168 citations

Activated ras alleles in human carcinoma of the prostate are rare.

1991 • 150 citations

K-ras activation in neoplasms of the human female reproductive tract.

1990 • 130 citations

Trends in Frequency of Latent Prostate Carcinoma in Japan from 1965-1979 to 1982-1986

1988 • 123 citations

Prevalence of Latent Prostate Carcinoma in Two U.S. Populations<xref ref-type="fn" rid="fn2">2</xref>

1980 • 106 citations

Activated ki‐ras oncogene in human prostatic adenocarcinoma

1987 • 92 citations

Molecular mechanisms of oncogenesis.

1989 • 84 citations

Oncogenes

1988 • 57 citations

Analysis of c-Ki-ras mutations in human colon carcinoma by cell sorting, polymerase chain reaction, and DNA sequencing.

1989 • 51 citations

Detection of activated Mr 21,000 protein, the product of ras oncogenes, using antibodies with specificity for amino acid 12.

1986 • 39 citations

Reported binding of monoclonal antibody RAP-5 to formalin-fixed tissue sections is not indicative of ras p21 expression

1988 • 37 citations

Heterogeneous Subpopulations of Human Prostatic Adenocarcinoma Cells: Potential Usefulness of P21 Protein as a Predictor for Bone Metastasis

1988 • 36 citations

Comparative immunohistochemical reactivity of monoclonal and polyclonal antibodies to H-ras p21 in normal and neoplastic tissues of rodents and humans.

1989 • 25 citations

Antibodies to ras oncogene p21 proteins lack immunohistochemical specificity for neoplastic epithelium in human prostate tissue.

1989 • 22 citations

Predictive factors in prostatic hyperplasia and neoplasia

1990 • 16 citations

Activation of c-ras oncogenes by mutations and amplification.

1986 • 12 citations