Pre-treatment number of clonogenic cells and their radiosensitivity are major determinants of local tumour control after fractionated irradiation
Data up to Jan 2025
Total Citations Per Year
Abstract
References (42)
Prospective identification of tumorigenic breast cancer cells
2003 • 10,067 citations
Identification of human brain tumour initiating cells
2004 • 7,166 citations
Bootstrap Methods for Standard Errors, Confidence Intervals, and Other Measures of Statistical Accuracy
1986 • 6,027 citations
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
2006 • 4,012 citations
Identification and expansion of human colon-cancer-initiating cells
2006 • 3,914 citations
Cancer Stem Cells—Perspectives on Current Status and Future Directions: AACR Workshop on Cancer Stem Cells
2006 • 2,961 citations
Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
2007 • 2,139 citations
A Tumorigenic Subpopulation with Stem Cell Properties in Melanomas
2005 • 1,263 citations
Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells
2006 • 951 citations
Inherent cellular radiosensitivity as a basic concept for human tumor radiotherapy
1981 • 530 citations
Basic Clinical Radiobiology
1997 • 501 citations
A critique of the evidence for active host defence against cancer, based on personal studies of 27 murine tumours of spontaneous origin
1976 • 478 citations
The radioresponsiveness of human tumours and the initial slope ofthe cell survival curve
1984 • 472 citations
Advances in Radiation Biology
1975 • 283 citations
The Four R's of Radiotherapy
1975 • 271 citations
Epidermal Growth Factor Receptor Expression in Pretreatment Biopsies From Head and Neck Squamous Cell Carcinoma As a Predictive Factor for a Benefit From Accelerated Radiation Therapy in a Randomized Controlled Trial
2005 • 245 citations
Basic Clinical Radiobiology
2024 • 209 citations
Tumor lactate content predicts for response to fractionated irradiation of human squamous cell carcinomas in nude mice
2006 • 180 citations
Cellular Radiation Biology
1974 • 170 citations
Rodent tumor models in experimental cancer therapy
1988 • 165 citations
Cellular Radiation Biology.
1965 • 160 citations
Quantifying the position and steepness of radiation dose-response curves
1997 • 147 citations
Clinical implications of heterogeneity of tumor response to radiation therapy
1992 • 142 citations
The proportion of stem cells in murine tumors
1989 • 116 citations
Response of human squamous cell carcinoma xenografts of different sizes to irradiation: relationship of clonogenic cells, cellular radiation sensitivity in vivo, and tumor rescuing units.
1990 • 109 citations
The prognostic value of epidermal growth factor receptor is related to tumor differentiation and the overall treatment time of radiotherapy in squamous cell carcinomas of the head and neck
2004 • 104 citations
In vitro intrinsic radiation sensitivity of glioblastoma multiforme
1992 • 104 citations
Pimonidazole labelling and response to fractionated irradiation of five human squamous cell carcinoma (hSCC) lines in nude mice: The need for a multivariate approach in biomarker studies
2006 • 101 citations
Response of Human Squamous Cell Carcinoma Xenografts of Different Sizes to Irradiation: Relationship of Clonogenic Cells, Cellular Radiation Sensitivity in Vivo, and Tumor Rescuing Units
1990 • 99 citations
The influence of epidermal growth factor receptor and tumor differentiation on the response to accelerated radiotherapy of squamous cell carcinomas of the head and neck in the randomized DAHANCA 6 and 7 study
2005 • 90 citations
Decreased repopulation as well as increased reoxygenation contribute to the improvement in local control after targeting of the EGFR by C225 during fractionated irradiation
2005 • 88 citations
Rodent tumor models in experimental cancer therapy
1987 • 86 citations
Assessment of local tumor control using censored tumor response data
1983 • 76 citations
Why are some human tumours more radiosensitive than others?
1989 • 75 citations
Preclinical evaluation of molecular-targeted anticancer agents for radiotherapy
2006 • 75 citations
Dose-response curve and split-dose recovery in human skin cancer
1984 • 62 citations
Does heterogeneity of pimonidazole labelling correspond to the heterogeneity of radiation-response of FaDu human squamous cell carcinoma?
2005 • 41 citations
Local tumor control following single dose irradiation of human melanoma xenografts: relationship to cellular radiosensitivity and influence of an immune response by the athymic mouse.
1989 • 39 citations
Animal Systems for Translational Research in Radiation Oncology
1999 • 27 citations
Quantitative Evaluation of the Effects of Cotransplantation of Heavily Irradiated Human Tumor Cells and of Different Immunosuppressive Measures on the Xenotransplantability of a Human Squamous-Cell Carcinoma into Athymic Nude Mice
1992 • 21 citations
Differentiation status of human squamous cell carcinoma xenografts does not appear to correlate with the repopulation capacity of clonogenic tumour cells during fractionated irradiation
2004 • 18 citations
The Effect of Whole-Body Irradiation of Nude Mice on the Tumor Transplantability and Control Probability of a Human Soft Tissue Sarcoma Xenograft
1996 • 17 citations