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Developmental and Functional Biology of the Primate Fetal Adrenal Cortex*

Data up to Jan 2025

Published1997
Citations639
References253

Total Citations Per Year

Abstract

References (253)

The Transforming Growth Factor-beta Family

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The Cloning of a Family of Genes That Encode the Melanocortin Receptors

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A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation

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Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures

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Developmental expression of mouse steroidogenic factor-1, an essential regulator of the steroid hydroxylases.

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Gonadal and extragonadal expression of inhibin alpha, beta A, and beta B subunits in various tissues predicts diverse functions.

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Plasma estrone, estradiol, estriol, progesterone, and 17-hydroxyprogesterone in human pregnancy

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The Mechanism of Initiation of Parturition in the Ewe

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Actions of Placental and Fetal Adrenal Steroid Hormones in Primate Pregnancy*

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Glucocorticoid stimulates expression of corticotropin-releasing hormone gene in human placenta.

1988 • 437 citations

Plasma Corticotropin-Releasing Hormone Concentrations During Pregnancy and Parturition*

1987 • 388 citations

Characterization of the mouse FTZ-F1 gene, which encodes a key regulator of steroid hydroxylase gene expression.

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The type 1 (EGFR-related) family of growth factor receptors and their ligands

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Expression of Somatomedin/Insulin-Like Growth Factor Messenger Ribonucleic Acids in the Human Fetus: Identification, Characterization, and Tissue Distribution*

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Steroidogenic factor I, a key regulator of steroidogenic enzyme expression, is the mouse homolog of fushi tarazu-factor I

1992 • 375 citations

Development of cancer cachexia-like syndrome and adrenal tumors in inhibin-deficient mice.

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Diverse forms of a receptor for acidic and basic fibroblast growth factors.

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Evidence for local stimulation of ACTH secretion by corticotropin-releasing factor in human placenta

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Coexpression of the sis and myc proto-oncogenes in developing human placenta suggests autocrine control of trophoblast growth

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Adrenarche: A Survey of Rodents, Domestic Animals, and Primates

1978 • 324 citations

Adrenocortical-related maturational events in the fetus

1976 • 293 citations

A New Cause of Female Pseudohermaphroditism: Placental Aromatase Deficiency

1991 • 281 citations

Identical origin of adrenal cortex and gonad revealed by expression profiles of Ad4BP/SF‐1

1996 • 280 citations

High Levels of Corticotropin-Releasing Hormone Immunoactivity in Maternal and Fetal Plasma during Pregnancy*

1986 • 280 citations

Immunoreactive Corticotropin-Releasing Hormone in Human Plasma During Pregnancy, Labor, and Delivery*

1987 • 270 citations

Characterization and gestational regulation of corticotropin-releasing hormone messenger RNA in human placenta.

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Corpus Luteum Angiogenic Factor Is Related to Fibroblast Growth Factor*

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Activin Receptors and Cellular Signaling by the Receptor Serine Kinase Family

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The Metabolic Clearance Rate, Blood Production, Interconversion and Transplacental Passage of Cortisol and Cortisone in Pregnancy Near Term

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Transforming Growth Factor β: Biochemistry and Roles in Embryogenesis, Tissue Repair and Remodeling, and Carcinogenesis

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Insulin-Like Growth Factor-ll (IGF-II): A Potential Autocrine/Paracrine Growth Factor for Human Breast Cancer Acting via the IGF-I Receptor

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Cortisol blockade of progesterone: A possible molecular mechanism involved in the initiation of human labor

1996 • 246 citations

The utilization of circulating dehydroisoandrosterone sulfate for estrogen synthesis during human pregnancy

1963 • 246 citations

Coordinate tropic hormone regulation of mRNAs for insulin-like growth factor II and the cholesterol side-chain-cleavage enzyme, P450scc [corrected], in human steroidogenic tissues.

1987 • 240 citations

Conversion of maternal cortisol to cortisone during placental transfer to the human fetus

1974 • 236 citations

The fibroblast growth factor family.

1990 • 219 citations

Regulation of the Primate Fetal Adrenal Cortex*

1990 • 209 citations

Failure of initiation of parturition after electrocoagulation of the pituitary of the fetal lamb

1967 • 207 citations

Orphan nuclear receptors--the first eight years.

1996 • 206 citations

CORTICOTROPIN-RELEASING FACTOR-LIKE ACTIVITY IN HUMAN PLACENTAL EXTRACTS

1982 • 203 citations

Control of Bovine Adrenal Cortical Cell Proliferation by Fibroblast Growth Factor. Lack of Effect of Epidermal Growth Factor

1977 • 201 citations

The Human Adrenal Cortex

1982 • 197 citations

IMMUNOREACTIVE CORTICOTROPIN-RELEASING FACTOR IS PRESENT IN HUMAN MATERNAL PLASMA DURING THE THIRD TRIMESTER OF PREGNANCY

1984 • 188 citations

The Localization and Distribution of Corticotropin-Releasing Hormone in the Human Placenta and Fetal Membranes throughout Gestation*

1991 • 181 citations

Serum Immunoreactive Somatomedin Levels in Normal Adults, Pregnant Women at Term, Children at Various Ages, and Children with Constitutionally Delayed Growth*

1981 • 181 citations

The corticotropin releasing hormone gene is expressed in human placenta

1987 • 179 citations

Placental Sulfatase Deficiency1

1969 • 175 citations

Molecular and clinical advances in congenital adrenal hyperplasia

1987 • 174 citations

Effects of Fibroblast and Epidermal Growth Factors on Ovarian Cell Proliferationin Vitro. I. Characterization of the Response of Granulosa Cells to FGF and EGF

1977 • 174 citations

Local stimulation of prostagiandin production by corttcotropin-releasing hormone in human fetal membranes and placenta

1989 • 169 citations

Biologically active corticotropin-releasing hormone in maternal and fetal plasma during pregnancy

1988 • 169 citations

Novel presence of luteinizing hormone/chorionic gonadotropin receptors in human adrenal glands.

1996 • 168 citations

Clinical and Molecular Genetics of Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency

1991 • 163 citations

Plasma ACTH Levels in the Human Fetus and Neonate as Related to Age and Parturition1

1974 • 160 citations

3β-Hydroxysteroid Dehydrogenase/Isomerase in the Fetal Zone and Neocortex of the Human Fetal Adrenal Gland*

1990 • 155 citations

Inhibition of replication of normal adrenocortical cells in culture by adrenocorticotropin.

1975 • 155 citations

Isolation of Fibroblast Growth Factor from Bovine Adrenal Gland: Physicochemical and Biological Characterization*

1986 • 145 citations

THE INFLUENCE OF ANENCEPHALY UPON INTRAUTERINE GROWTH OF FETUS AND PLACENTA AND UPON GESTATION LENGTH

1973 • 144 citations

Insulin-like growth factors (IGFs) and their receptors in adrenal tumors: high IGF-II expression in functional adrenocortical carcinomas.

1993 • 143 citations

Insulin-like growth factors enhance steroidogenic enzyme and corticotropin receptor messenger ribonucleic acid levels and corticotropin steroidogenic responsiveness in cultured human adrenocortical cells.

1996 • 139 citations

Adrenals in anencephaly and hydrocephaly.

1956 • 138 citations

THE SITE OF PRODUCTION OF OESTROGENIC HORMONES IN HUMAN PREGNANCY

1961 • 137 citations

Regulation of gonadotropin receptors, gonadotropin responsiveness, and cell multiplication by somatomedin‐C and insulin in cultured pig Leydig cells

1986 • 137 citations

Localization of cytochrome P450 cholesterol side-chain cleavage, cytochrome P450 17 alpha-hydroxylase/17, 20-lyase, and 3 beta-hydroxysteroid dehydrogenase isomerase steroidogenic enzymes in human and rhesus monkey fetal adrenal glands: reappraisal of functional zonation.

1993 • 135 citations

Dexamethasone and estradiol treatment in pregnant rhesus macaques: Effects on gestational length, maternal plasma hormones, and fetal growth

1983 • 135 citations

An Autocrine/Paracrine Role forInsulin-Like Growth Factors inthe Regulation ofHuman Placental Growth*

1986 • 133 citations

The genesis of cell types in the adenohypophysis of the human fetus as observed with immunocytochemistry

1975 • 130 citations

In Vitro Biosynthesis and Comparative Posttranslational Processing of Immunoreactive Precursor Corticotropin/β-Endorphin by Human Placental and Pituitary Cells*

1980 • 129 citations

Role of hCG in Regulation of the Fetal Zone of the Human Fetal Adrenal Gland*

1978 • 126 citations

Characterization of Insulin-Like Growth Factor I and Insulin Receptors on Cultured Bovine Adrenal Fasciculata Cells. Role of these Peptides on Adrenal Cell Function*

1988 • 126 citations

Hormonal Control of Adrenocortical Cell Proliferation

1977 • 124 citations

Mitogenic action, regulation, and localization of insulin-like growth factors in the human fetal adrenal gland.

1993 • 123 citations

Presence of Corticotropin in Human Placenta: Demonstration ofin VitroSynthesis

1977 • 120 citations

Steroid Production by Definitive and Fetal Zones of the Human Fetal Adrenal Gland*

1978 • 119 citations

Activin and inhibin in the human adrenal gland. Regulation and differential effects in fetal and adult cells.

1992 • 119 citations

Development of Activity of 3β-Hydroxysteroid Dehydrogenase in Human Fetal Tissues and in Two Anencephalic Newborns

1966 • 118 citations

Actions of placental and fetal adrenal steroid hormones in primate pregnancy

1995 • 117 citations

Production of premature delivery in pregnant rhesus monkeys by androstenedione infusion

1996 • 116 citations

STUDIES ON THE AROMATISATION OF NEUTRAL STEROIDS IN PREGNANT WOMEN

1964 • 116 citations

Placental corticotrophin releasing factor may modulate human parturition

1989 • 115 citations

Physiological Disposition of 4-C14-Cortisol During Late Pregnancy1

1957 • 114 citations

A Study of a Pregnancy with Low Estrogen Production Due to Placental Sulfatase Deficiency

1973 • 108 citations

The identification of a human myometrial corticotropin-releasing hormone receptor that increases in affinity during pregnancy.

1993 • 107 citations

Variegated expression of a mouse steroid 21-hydroxylase/beta- galactosidase transgene suggests centripetal migration of adrenocortical cells.

1996 • 107 citations

Fibroblast growth factor in the human placenta

1985 • 107 citations

Identification of a Putative Steroidogenic Factor-1 Response Element in the DAX-1 Promoter

1995 • 107 citations

The Changing Response Pattern of Sheep Fetal Adrenal Cells throughout the Course of Gestation*

1980 • 106 citations

Conversion of H3-Dehydroisoandrosterone (3β-Hydroxy-Δ5-androsten-17-one) Sulfate to H3-Estrogens in Normal Pregnant Women

1963 • 106 citations

Insulin-Like Growth Factors Augment Steroid Production and Expression of Steroidogenic Enzymes in Human Fetal Adrenal Cortical Cells: Implications for Adrenal Androgen Regulation1

1997 • 105 citations

Differential effects of transforming growth factor type beta on the growth and function of adrenocortical cells in vitro.

1986 • 103 citations

Development of zonular patterns in the human adrenal gland

1968 • 100 citations

Isolation and Characterization of a Corticotropin-Releasing Hormone-Like Peptide From Human Placenta

1988 • 99 citations

Diagnosis of X-linked Adrenal Hypoplasia Congenita by Mutation Analysis of the DAX1 Gene

1995 • 98 citations

THE FETAL ZONE OF THE ADRENAL GLAND

1953 • 97 citations

Corticotropin-Releasing Hormone and Oxytocin Stimulate the Release of Placental Proopiomelanocortin Peptides

1988 • 96 citations

ENDOCRINE FUNCTIONS OF THE HUMAN FETOPLACENTAL UNIT.

1964 • 94 citations

Metabolism of C-16-oxygenated Steroids by Human Placenta: the Formation of Estriol

1959 • 93 citations

Regulation of the Fetal Human Adrenal Cortex: Effects of Adrenocorticotropin on Growth and Function of Monolayer Cultures of Fetal and Definitive Zone Cells*

1981 • 90 citations

Corticotrophin-releasing factor in human placenta: Localization, concentration and release in vitro

1988 • 90 citations

Activin-A as an intraovarian modulator: actions, localization, and regulation of the intact dimer in human ovarian cells.

1992 • 87 citations

The Control of Steroidogenesis by Human Fetal Adrenal Cells in Tissue Culture. IV.The Effects of Exposure to Placental Steroids*

1982 • 87 citations

Observations on the Development of the Human Suprarenal Gland.

1927 • 86 citations

In UteroRegulation of Rhesus Monkey Fetal Adrenals: Effects of Dexamethasone, Adrenocorticotropin, Thyrotropin-Releasing Hormone, Prolactin, Human Chorionic Gonadotropin, and α-Melanocyte-Stimulating Hormone on Fetal and Maternal Plasma Steroids*

1979 • 85 citations

STEROID HYDROXYLATION IN HUMAN FETAL ADRENALS: FORMATION OF 16±-HYDROXYPROGESTERONE, 17-HYDROXYPROGESTERONE AND DEOXYCORTICOSTERONE1

1961 • 85 citations

Corticotropin-releasing hormone increases prostaglandin F2α activity on human myometrium in vitro

1994 • 84 citations

Basic fibroblast growth factor expression is regulated by corticotropin in the human fetal adrenal: a model for adrenal growth regulation.

1991 • 84 citations

Hormone Synthesis and Release from Human Fetal Adenohypophysesin Vitro

1974 • 84 citations

Novel presence of luteinizing hormone/chorionic gonadotropin receptors in human adrenal glands

1996 • 84 citations

Formation and Metabolism of Steroids in the Fetus and Placenta

1967 • 83 citations

Genomic sequence of the DAX1 gene: an orphan nuclear receptor responsible for X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism.

1996 • 81 citations

The gene responsible for adrenal hypoplasia congenita, DAX-1, encodes a nuclear hormone receptor that defines a new class within the superfamily.

1996 • 79 citations

α-Inhibin Gene Expression Occurs in the Ovine Adrenal Cortex, and is Regulated by Adrenocorticotropin

1987 • 78 citations

The Fetal Adrenal Gland

1981 • 78 citations

Neutral C19-steroids and steroid sulfates in human pregnancy II. Dehydroepiandrosterone sulfate, 16α-hydroxydehydroepi-androsterone, and 16α-hydroxydehydroepiandrosterone sulfate in maternal and fetal blood of pregnancies with anenphalic and normal fetuses

1966 • 78 citations

Insulin-Like Growth Factors Augment Steroid Production and Expression of Steroidogenic Enzymes in Human Fetal Adrenal Cortical Cells: Implications for Adrenal Androgen Regulation

1997 • 78 citations

Cell proliferation and displacement in the adrenal cortex of young rats injected with tritiated thymidine

1963 • 77 citations

Orphan nuclear receptors--the first eight years

1996 • 76 citations

Control of Proliferation of Human Fetal Adrenal Cells in Vitro*

1981 • 76 citations

Morphologic features of the anencephlaic adrenal gland in early pregnancy

1980 • 76 citations

Regulation and Function of the Primate Fetal Adrenal Gland and Gonad

1981 • 75 citations

The foetal adrenal cortex in the human. Its ultrastructure at different stages of development and in different functional states.

1968 • 74 citations

Corticotropin-releasing factor and parturition: plasma and amniotic fluid levels and placental binding sites.

1990 • 72 citations

Transplacental passage and fetal secretion of aldosterone

1970 • 71 citations

Insulin-like growth factors (IGFs) and their receptors in adrenal tumors: high IGF-II expression in functional adrenocortical carcinomas

1993 • 71 citations

The Maternal-Fetal Cortisol Gradient During Pregnancy and at Delivery1

1977 • 71 citations

Synthesis in Vitro of Steroids by Human Fetal Adrenal Gland Slices

1959 • 70 citations

Stimulation of Division of Yl Adrenal Cells by a Growth Factor Isolated from Bovine Pituitary Glands

1975 • 67 citations

HORMONE PRODUCTION OF THE ISOLATED HUMAN PLACENTA

1959 • 67 citations

The regulation of adrenocortical function by control of growth and structure

1985 • 66 citations

Basic Fibroblast Growth Factor: Production and Growth Stimulation in Cultured Adrenal Cortex Cells*

1987 • 66 citations

The Effects of Dexamethasone on Plasma Steroid Levels and Fetal Adrenal Histology in the Pregnant Rhesus Monkey

1974 • 66 citations

Observations on the ultrastructure of cytodifferentiation in the human fetal adrenal cortex.

1970 • 65 citations

Studies on the involution of the fetal cortex of the adrenal glands.

1940 • 65 citations

The Regulation of Transplacental Cortisol- Cortisone Metabolism by Estrogen in Pregnant Baboons*

1988 • 64 citations

Low Expression of 3β-Hydroxy-5-Ene Steroid Dehydrogenase Gene in Human Fetal Adrenalsin Vivo; Adrenocorticotropin and Protein Kinase C-Dependent Regulation in Adrenocortical Cultures

1991 • 64 citations

Hormonal Regulation of Insulin-Like Growth Factor I Secretion by Bovine Adrenal Cells

1989 • 63 citations

Steroid hormone receptors in the adrenal glands of fetal and adult rhesus monkeys.

1992 • 63 citations

Type β transforming growth factor is a potent modulator of differentiated adrenocortical cell functions

1986 • 62 citations

Fetal endocrinology: An experimental approach

1976 • 62 citations

Human Recombinant Activin-A Inhibits Proliferation of Human Fetal Adrenal CellsIn Vitro*

1990 • 62 citations

Characterization and regulation of somatomedin‐C/insulin‐like growth factor I (Sm‐C/IGF‐I) receptors on cultured pig Leydig cells

1987 • 61 citations

Transforming growth factor β treatment decreases ACTH receptors on ovine adrenocortical cells

1989 • 61 citations

The early embryological development of the fetal and permanent adrenal cortex in man

1940 • 60 citations

Interaction of Epidermal Growth Factor With the Hypothalamic-Pituitary-Adrenal Axis: Potential Physiologic Relevance*

1988 • 59 citations

Corticotrophin-releasing hormone and β-endorphin in labour

1994 • 58 citations

Functional maturation of the primate fetal adrenal in vivo. II. Ontogeny of corticosteroid synthesis is dependent upon specific zonal expression of 3 beta-hydroxysteroid dehydrogenase/isomerase.

1996 • 58 citations

Insulin-Like Growth Factors (IGF5) as Autocrine/Paracrine Regulators of Granulosa Cell Differentiation and Growth: Studies with a Neutralizing Monoclonal Antibody to IGF-I1

1989 • 57 citations

Interaction of insulin-like growth factor-II and estradiol directs steroidogenesis in the human fetal adrenal toward dehydroepiandrosterone sulfate production.

1993 • 56 citations

Hypophysiotropic and neuromodulatory regulation of adrenocorticotropin in the human fetal pituitary gland.

1986 • 56 citations

Functional maturation of the primate fetal adrenal in vivo: I. Role of insulin-like growth factors (IGFs), IGF-I receptor, and IGF binding proteins in growth regulation.

1996 • 56 citations

Bovine adrenocortical cells exhibit high affinity transforming growth factor-beta receptors which are regulated by adrenocorticotropin.

1988 • 55 citations

The Steroid Hormonal Milieu of the Undisturbed Human Fetus and Mother at 16–20 Weeks Gestation*

1991 • 55 citations

Transuteroplacental Metabolism of Cortisol and Cortisone during Mid- and Late Gestation in the Baboon*

1984 • 54 citations

Steroidogenic activity of hACTH and related peptides on the human neocortex and fetal adrenal cortex in organ culture

1978 • 54 citations

Effects of transforming growth factor beta on ovine adrenocortical cells

1988 • 54 citations

Immunohistochemical evaluation of the cellular localization and ontogeny of 3β-hydroxysteroid dehydrogenase/delta 5-4 isomerase in the human fetal adrenal gland

1995 • 52 citations

Regulation of corticotropin and steroidogenic enzyme mRNAs in human fetal adrenal cells by corticotropin, angiotensin-II and transforming growth factor β1

1994 • 52 citations

THE ADRENAL FETAL ZONE: ITS OCCURRENCE IN PRIMATES AND A POSSIBLE RELATIONSHIP TO CHORIONIC GONADOTROPIN1

1957 • 50 citations

AN ATTEMPT TO DEMONSTRATE CELL MIGRATION FROM THE ZONA GLOMERULOSA IN THE PREPUBERTAL MALE RAT ADRENAL CORTEX

1973 • 50 citations

Transforming growth factor alpha, epidermal growth factor, and epidermal growth factor receptor expression in normal and diseased human adrenal cortex by immunohistochemistry and in situ hybridization.

1994 • 49 citations

THE EFFECT OF HYPOPHYSIAL HORMONES AND HUMAN CHORIONIC GONADOTROPHIN (HCG) ON THE ANENCEPHALIC FETAL ADRENAL CORTEX AND ON PARTURITION IN THE HUMAN

1974 • 49 citations

Receptors for insulin and insulin-like growth factor-I in the human adrenal gland

1989 • 48 citations

Effects of transforming growth factor-β on human fetal adrenal steroid production

1994 • 47 citations

SOME NEW THOUGHTS ON THE FETOPLACENTAL UNIT AND PARTURITION IN PRIMATES

1981 • 45 citations

CELL PROLIFERATION IN THE PREPUBERTAL MALE RAT ADRENAL CORTEX: AN AUTORADIOGRAPHIC STUDY

1971 • 45 citations

Serum and growth factor requirements for proliferation of human adrenocortical cells in culture: Comparison with bovine adrenocortical cells

1983 • 44 citations

Synergistic effects of corticotropin and insulin-like growth factor I on corticotropin receptors and corticotropin responsiveness in cultured bovine adrenocortical cells

1989 • 43 citations

Experimental Fetal Anencephaly in the Rhesus Monkey: Effect on Gestational Length and Fetal and Maternal Plasma Steroids

1977 • 43 citations

Activation of the baboon fetal pituitary-adrenocortical axis at midgestation by estrogen: enhancement of fetal pituitary proopiomelanocortin messenger ribonucleic acid expression.

1994 • 42 citations

Epidermal growth factor acts as a corticotropin-releasing factor in chronically catheterized fetal lambs.

1987 • 42 citations

Ontogeny of 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase (3β-HSD) in human adrenal gland performed by immunocytochemistry

1990 • 42 citations

Aldosterone biosynthesis by human fetal adrenal in vitro

1969 • 41 citations

The effect of adrenocorticotropic hormone and dexamethasone, administered to the fetus in utero, upon maternal and fetal estrogens

1972 • 41 citations

A role for epidermal growth factor in the morphological and functional maturation of the adrenal gland in the fetal rhesus monkey in vivo.

1996 • 41 citations

LEVELS OF CHORIONIC GONADOTROPHIN IN THE NEWBORN INFANT AND THEIR RELATIONSHIP TO ADRENAL DEHYDROEPIANDROSTERONE

1967 • 41 citations

Effect of estrogen on dehydroepiandrosterone formation by baboon fetal adrenal cells in vitro

1987 • 40 citations

The angiotensin AT2 receptor is present in the human fetal adrenal gland throughout the second trimester of gestation.

1996 • 40 citations

Synthetic corticotropin-releasing factor stimulates secretion of immunoreactive β-endorphin/β-lipotropin and ACTH by human fetal pituitaries in vitro

1983 • 39 citations

The histogenesis of the rat adrenal cortex: A study based on histologic analysis of mosaic pattern in chimeras

1987 • 39 citations

Spontaneous and Adrenocorticotropin (ACTH)-Induced Maturation of the Responsiveness of Ovine Fetal Adrenal Cells to in Vitro Stimulation by ACTH and Cholera Toxin*

1981 • 38 citations

Effects of insulin-like growth factor I (IGF-I) on enzymatic activity in human adrenocortical cells. Interactions with ACTH

1991 • 38 citations

LEVELS OF 17-HYDROXYCORTICOSTEROIDS AND 17-KETOSTEROIDS IN MATERNAL AND CORD PLASMA IN TERM ANENCEPHALY*†

1958 • 37 citations

Localization and regulation of corticotropin receptor expression in the midgestation human fetal adrenal cortex: implications for in utero homeostasis.

1996 • 37 citations

Effects of Synthetic Corticotropin-Releasing Factor and Dopamine on the Release of Immunoreactive β-Endorphin/β-Lipotropin and α-Melanocyte-Stimulating Hormone from Human Fetal Pituitariesin Vitro*

1982 • 36 citations

The effects of progesterone, pregnenolone, estriol, ACTH and hCG on steroid secretion of cultured human fetal adrenals

1979 • 36 citations

In Vitro Effect of Insulin and Insulin-Like Growth Factor-I on Cell Multiplication and Adrenocorticotropin Responsiveness of Fetal Adrenal Cells1

1989 • 35 citations

Cytogenesis in the rat adrenal cortex: evidence for an ACTH-induced centripetal cell migration from the zona glomerulosa.

1978 • 35 citations

ENDOCRINOLOGY OF PARTURITION

1981 • 34 citations

Biosynthesis of aldosterone by human foetuses perfused with corticosterone at mid-term

1966 • 33 citations

Steroid hormone receptors in the adrenal glands of fetal and adult rhesus monkeys

1992 • 33 citations

Growth‐inhibitory effect of TGF‐B on human fetal adrenal cells in primary monolayer culture

1989 • 33 citations

Maintenance of Cell Proliferation and Steroidogenesis in Cultured Human Fetal Adrenal Cells Chronically Exposed to Adrenocorticotropic Hormone: Rationalization of in Vitro and in Vivo Findings1

1990 • 33 citations

The adrenal cortex in the fetus and neonate

1985 • 33 citations

STEROID ARTERIOVENOUS DIFFERENCES IN UMBILICAL CORD PLASMA: EVIDENCE OF CORTISOL PRODUCTION BY THE HUMAN FETUS IN EARLY GESTATION

1973 • 33 citations

Receptor autoradiographic localization of insulin-like growth factor-I (IGF-I) binding sites in human fetal and adult adrenal glands

1989 • 32 citations

Chronic administration of low doses of adrenocorticotropin to hypophysectomized fetal sheep leads to normal term labor.

1994 • 30 citations

Inhibin and Activin in Reproductive Biology

1992 • 29 citations

Insulin-like growth factor binding proteins in the human adrenal gland

1993 • 28 citations

Human Fetal Endocrines

1980 • 28 citations

Biosynthesis ofcortisol from 3β, 17α,21-trihydroxypregn-5-en-20-one by the intact human foetus at midpregnancy

1968 • 27 citations

Somatomedin Receptors: Structure, Function, and Regulation

1986 • 27 citations

Effects of adrenalectomy on pregnancy length in the rhesus monkey

1972 • 27 citations

Basic fibroblast growth factor receptor in the rat adrenal cortex: effects of suramin and unilateral adrenalectomy on receptor numbers.

1994 • 27 citations

Genomic sequence of the DAX1 gene: an orphan nuclear receptor responsible for X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism

1996 • 27 citations

Modulation of Adrenocorticotropin-Stimulated Baboon Fetal Adrenal Dehydroepiandrosterone Formationin Vitroby Estrogen at Mid- and Late Gestation*

1990 • 26 citations

Human Fetal Adrenal Definitive and Fetal Zone Metabolism of Pregnenolone and Corticosterone: Alternate Biosynthetic Pathways and Absence of Detectable Aldosterone Synthesis*

1990 • 26 citations

Evidence for Autonomous Pituitary-Adrenal Function in the Near-Term Fetal Rhesus (Macaca mulatta)1

1972 • 26 citations

Biphasic developmental expression of adrenocorticotropin receptor messenger ribonucleic acid levels in the baboon fetal adrenal gland.

1996 • 25 citations

Effect of Estrogen on Pituitary Peptide-Induced Dehydroepiandrosterone Secretion in the Baboon Fetus at Midgestation*

1989 • 25 citations

In the rhesus monkey placental retention after fetectomy at 121 to 130 days' gestation outlasts the normal duration of pregnancy

1992 • 25 citations

Regulation of Adrenal Growth. Differences in the Effects of ACTH in Normal and Dexamethasone-Suppressed Guinea Pigs1

1968 • 25 citations

HCG + ACTH Stimulation of in vitro dehydroepiandrosterone production in human fetal adrenals from precursor cholesterol and Δ-pregnenolone

1975 • 24 citations

The effect of synthetic acth on the metabolism of [4-14C]-progesterone by the previable human fetus

1977 • 23 citations

The angiotensin AT2 receptor is present in the human fetal adrenal gland throughout the second trimester of gestation

1996 • 23 citations

STUDIES ON THE INVOLUTION OF THE FETAL CORTEX OF THE ADRENAL GLANDS

1941 • 23 citations

Transforming growth factor-beta 1 inhibits aldosterone and stimulates adrenal renin in cultured bovine zona glomerulosa cells.

1992 • 22 citations

Cortisol-Cortisone Interrelationship in the Late Gestation Rhesus Monkey Fetus in Utero*

1982 • 22 citations

Placental origin of the suppression of 3β-hydroxysteroid dehydrogenase in the fetal zone cells of human fetal adrenals

1980 • 22 citations

Hamster Placental Lactogen-ll Contains a Structural Feature Unique among the Growth Hormone-Prolactin-Placental Lactogen Family

1989 • 21 citations

Responsiveness and Maximum Secretory Capacity of Isolated Fetal Lamb Adrenocortical Cells throughout the Last Third of Gestation*

1980 • 20 citations

Microscopic comparison of the normal and anencephalic human adrenal gland with emphasis on the transient-zone.

1970 • 20 citations

A role for epidermal growth factor in the morphological and functional maturation of the adrenal gland in the fetal rhesus monkey in vivo

1996 • 19 citations

Effect of Estrogen on the Metabolism of Cortisol and Cortisone in the Baboon Fetus at Midgestation1

1988 • 19 citations

Corticotropin releasing hormone- and adreno-corticotropin-like immunoreactivity in human placenta, peripheral and uterine vein plasma.

1987 • 19 citations

Sex Determination and Differentiation

2014 • 19 citations

DEVELOPMENT OF THE FETAL ADRENALS IN NONHUMAN PRIMATES: ELECTRON MICROSCOPY

1981 • 18 citations

The effect of estrogen on placental delivery after fetectomy in baboons

1989 • 17 citations

Maternal and Fetal Production Rates of Progesterone in Rhesus Macaques: Placental Transfer and Conversion to Cortisol*

1985 • 17 citations

Adrenocorticotropin interferes with transforming growth factor-beta-induced growth inhibition of neocortical cells from the human fetal adrenal gland.

1992 • 16 citations

Regulation of corticotropin responsiveness in human fetal adrenal cells

1991 • 14 citations

ADRENOCORTICAL RESPONSE UPON REPEATED STIMULATION WITH CORTICOTROPHIN IN PATIENTS LACKING ENDOGENOUS CORTICOTROPHIN SECRETION

1977 • 14 citations

Response to hemorrhagic stress in the rhesus monkey fetus in utero: effects on the pituitary-adrenal axis.

1993 • 13 citations

The utilization of placental substrates for cortisol synthesis by the baboon fetus near term

1980 • 13 citations

Localization and regulation of corticotropin receptor expression in the midgestation human fetal adrenal cortex: implications for in utero homeostasis

1996 • 13 citations

Receptor binding of transforming growth factor-β by human fetal adrenal cells

1995 • 12 citations

Aldosterone and corticosterone in amniotic fluid during various stages of pregnancy

1980 • 10 citations

The effects of human chorionic gonadotropin on growth and steroidogenesis of the human fetal adrenal gland in vitro

1987 • 10 citations

Fetectomy alters maternal endocrine and uterine activity rhythms in rhesus macaques during late gestation

1993 • 10 citations

Regulation of mineralocorticoid secretion by the superfused fetal monkey adrenal gland: lack of stimulation of aldosterone by ACTH.

1990 • 9 citations

POSTNATUM EVOLUTION OF THE ADRENAL GLANDS OF RHESUS MACAQUES

1981 • 9 citations

STEROID HORMONES IN PREGNANCY: THE BABOON AS A MODEL FOR STUDIES ON OESTROGEN SYNTHESIS

1972 • 9 citations

Adrenocorticotropic Hormone does not Induce Desensitization in Human Adrenal Cells during Fetal Life1

1988 • 8 citations

The effect of adrenocorticotropic hormone infusion on subsequent pituitary response in the sheep fetus

1990 • 4 citations

ACTH increases vascular endothelial growth factor expression in human fetal adrenal cortical cells:

1996 • 1 citations

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Developmental and Functional Biology of the Primate Fetal Adrenal Cortex* (1997) – Endocrine Reviews | Metascience Observatory Explorer