Estrogens modulate experimentally induced apoptosis of granule cells in the adult hippocampus

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats

1965 • 3,461 citations

Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator

1991 • 2,982 citations

Brain Maps: Structure of the Rat Brain

1992 • 1,873 citations

Brain maps: structure of the rat brain

1993 • 1,678 citations

Estrogen Replacement Therapy for Treatment of Mild to Moderate Alzheimer Disease

2000 • 985 citations

A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease

1997 • 965 citations

Estrogen Therapy in Postmenopausal Women

1998 • 927 citations

Estrogen Deficiency and Risk of Alzheimer's Disease in Women

1994 • 843 citations

Estradiol Increases the Sensitivity of Hippocampal CA1 Pyramidal Cells to NMDA Receptor-Mediated Synaptic Input: Correlation with Dendritic Spine Density

1997 • 679 citations

Gender Differences in Acute CNS Trauma and Stroke: Neuroprotective Effects of Estrogen and Progesterone

2000 • 640 citations

17-β Estradiol Protects Neurons from Oxidative Stress-Induced Cell Death in Vitro

1995 • 612 citations

Estrogen for Alzheimer’s disease in women

2000 • 555 citations

Estradiol Protects against Ischemic Injury

1998 • 548 citations

Identification of a putative estrogen response element in the gene encoding brain-derived neurotrophic factor.

1995 • 542 citations

Estrogen receptor alpha , not beta , is a critical link in estradiol-mediated protection against brain injury

2001 • 539 citations

Apoptosis-the molecular basis of cell death

1992 • 517 citations

Chapter 1 Chapter Neurons, numbers and the hippocampal network

1990 • 508 citations

The effect of ovariectomy and estradiol replacement on brain-derived neurotrophic factor messenger ribonucleic acid expression in cortical and hippocampal brain regions of female Sprague-Dawley rats.

1995 • 422 citations

Microtubules

1984 • 405 citations

Ischemic Stroke Risk With Oral Contraceptives

2000 • 397 citations

Estrogen as a Neuroprotectant in Stroke

2000 • 397 citations

Differential Regulation of NMDAR1 mRNA and Protein by Estradiol in the Rat Hippocampus

1996 • 376 citations

Estrogen-Mediated Neuroprotection After Experimental Stroke in Male Rats

1998 • 362 citations

Effects of estrogen on cognition, mood, and cerebral blood flow in AD

2000 • 292 citations

Morphological abnormalities in the brains of estrogen receptor β knockout mice

2001 • 265 citations

Effects of Estrogen Replacement on the Relative Levels of Choline Acetyltransferase, trkA, and Nerve Growth Factor Messenger RNAs in the Basal Forebrain and Hippocampal Formation of Adult Rats

1994 • 232 citations

Estrogen-Related Gender Difference in Survival Rate and Cortical Blood Flow After Impact-Acceleration Head Injury in Rats

2000 • 224 citations

Neuroprotective Effects of Estradiol in Middle-Aged Female Rats¹

2001 • 195 citations

Neuroprotective Effects of Estrogens on Hippocampal Cells in Adult Female Rats After Status Epilepticus

2000 • 161 citations

The Estrogen/Neurotrophin Connection during Neural Development: Is Co-Localization of Estrogen Receptors with the Neurotrophins and Their Receptors Biologically Relevant?

1996 • 154 citations

Stroke in Estrogen Receptor-α–Deficient Mice

2000 • 144 citations

Estrogen Decreases Infarct Size After Temporary Focal Ischemia in a Genetic Model of Type 1 Diabetes Mellitus

2000 • 113 citations

The women's health initiative estrogen replacement therapy is neurotrophic and neuroprotective

2000 • 107 citations

Ischemic Stroke and Use of Estrogen and Estrogen/Progestogen as Hormone Replacement Therapy

1998 • 102 citations

In Situ Labeling of Dying Cortical Neurons in Normal Aging and in Alzheimer's Disease: Correlations with Senile Plaques and Disease Progression

1996 • 94 citations

Estradiol Protects Against Ischemic Brain Injury in Middle-Aged Rats1

2000 • 92 citations

Effect of Endogenous Estrogen on Blood Flow Through Carotid Arteries

2001 • 85 citations

Deafferentation Causes Apoptosis in Cortical Sensory Neurons in the Adult Rat

1997 • 81 citations

Estrogens Decrease Reperfusion-Associated Cortical Ischemic Damage

2001 • 65 citations

Oral Contraceptives and Stroke

2000 • 63 citations

Apoptosis Versus Necrosis

1999 • 60 citations

Comparison of the neurotoxic effects of colchicine, the vinca alkaloids, and other microtubule poisons

1989 • 41 citations

Gender differences and the effects of synthetic exogenous and non-synthetic estrogens in focal cerebral ischemia

2000 • 38 citations

Biological Therapies for Alzheimer's Disease: Focus on Trophic Factors

1996 • 36 citations

Apoptosis in rat hippocampal dentate gyrus after intraventricular colchicine

1997 • 23 citations

Cell Death and Diseases of the Nervous System

1999 • 16 citations

Post-Menopausal Hormone Replacement Therapy and Stroke Risk

2000 • 14 citations