Caudal Granular Insular Cortex Is Sufficient and Necessary for the Long-Term Maintenance of Allodynic Behavior in the Rat Attributable to Mononeuropathy

Quantitative assessment of tactile allodynia in the rat paw

1994 • 6,953 citations

A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man

1988 • 5,129 citations

Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence

1993 • 2,006 citations

Mechanisms of Neuropathic Pain

2006 • 1,336 citations

Models and Mechanisms of Hyperalgesia and Allodynia

2009 • 1,060 citations

Chronic pain and medullary descending facilitation

2002 • 968 citations

Painful neuropathy: altered central processing maintained dynamically by peripheral input

1992 • 770 citations

Towards a theory of chronic pain

2008 • 759 citations

Afferent connections to the sensory trigeminal nuclei, the nucleus of the solitary tract and adjacent structures. An experimental study in the rat

1956 • 754 citations

Central nervous system mechanisms of pain modulation

2006 • 717 citations

Representation of Pain and Somatic Sensation in the Human Insula: a Study of Responses to Direct Electrical Cortical Stimulation

2002 • 539 citations

Non‐stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll‐like receptor 4 (TLR4)

2008 • 378 citations

Alleviating Neuropathic Pain Hypersensitivity by Inhibiting PKMζ in the Anterior Cingulate Cortex

2010 • 373 citations

Time-Dependent Descending Facilitation from the Rostral Ventromedial Medulla Maintains, But Does Not Initiate, Neuropathic Pain

2002 • 343 citations

Analgesia and hyperalgesia from GABA-mediated modulation of the cerebral cortex

2003 • 332 citations

Genetic enhancement of inflammatory pain by forebrain NR2B overexpression

2001 • 324 citations

Intrathecal HIV-1 Envelope Glycoprotein gp120 Induces Enhanced Pain States Mediated by Spinal Cord Proinflammatory Cytokines

2001 • 320 citations

Fitting the psychometric function

1999 • 306 citations

A new model of sciatic inflammatory neuritis (SIN): induction of unilateral and bilateral mechanical allodynia following acute unilateral peri-sciatic immune activation in rats

2001 • 304 citations

Mechanisms of touch-evoked pain (allodynia): a new model

1996 • 283 citations

Thermal hyperalgesia and mechanical allodynia produced by intrathecal administration of the human immunodeficiency virus-1 (HIV-1) envelope glycoprotein, gp120

2000 • 273 citations

Efficient estimation of sensory thresholds

1986 • 259 citations

Parsing Pain Perception Between Nociceptive Representation and Magnitude Estimation

2008 • 234 citations

Neuropathic pain and injured nerve: Peripheral mechanisms

1991 • 228 citations

The origin of corticospinal projection neurons in rat

1987 • 224 citations

A qualitative and quantitative analysis of the distributions of cells in the spinal cord and spinomedullary junction projecting to the thalamus of the rat

1986 • 209 citations

Allodynia after lateral-medullary (Wallenberg) infarct. A PET study

1998 • 196 citations

Somatotopic organization of pain responses to direct electrical stimulation of the human insular cortex

2009 • 192 citations

Trigeminal Neuropathic Pain Alters Responses in CNS Circuits to Mechanical (Brush) and Thermal (Cold and Heat) Stimuli

2006 • 191 citations

Repeated intrathecal injections of plasmid DNA encoding interleukin-10 produce prolonged reversal of neuropathic pain

2006 • 176 citations

Dopamine Reuptake Inhibition in the Rostral Agranular Insular Cortex Produces Antinociception

1999 • 149 citations

A PET activation study of brush-evoked allodynia in patientswith nerve injury pain

2005 • 137 citations

Auditory, Somatosensory, and Multisensory Insular Cortex in the Rat

2008 • 137 citations

Nociceptive behavior in animal models for peripheral neuropathy: Spinal and supraspinal mechanisms

2008 • 126 citations

An Opioidergic Cortical Antinociception Triggering Site in the Agranular Insular Cortex of the Rat that Contributes to Morphine Antinociception

1996 • 116 citations

Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain

2006 • 103 citations

Electrolytic lesion of the anterior cingulate cortex decreases inflammatory, but not neuropathic nociceptive behavior in rats

2001 • 101 citations

The Blockade of the Transient Receptor Potential Vanilloid Type 1 and Fatty Acid Amide Hydrolase Decreases Symptoms and Central Sequelae in the Medial Prefrontal Cortex of Neuropathic Rats

2011 • 81 citations

Calibrated Forceps: A Sensitive and Reliable Tool for Pain and Analgesia Studies

2006 • 71 citations

Hemispheric Mapping of Secondary Somatosensory Cortex in the Rat

2006 • 64 citations

Pain-related aversion and Fos expression in the central nervous system in rats

2003 • 62 citations

Insular cortex lesion diminishes neuropathic and inflammatory pain‐like behaviours

2010 • 58 citations

Responses of dorsal column nuclei neurons in rats with experimental mononeuropathy

1998 • 56 citations

Pharmacological characteristics of the hind paw weight bearing difference induced by chronic constriction injury of the sciatic nerve in rats

2009 • 46 citations

Attenuation of neuropathic manifestations by local block of the activities of the ventrolateral orbito-frontal area in the rat

2003 • 46 citations

An investigation of pyramidal tract cells in the somatosensory cortex of the rat

1968 • 40 citations

The role of the dorsal columns in neuropathic behavior: evidence for plasticity and non-specificity

2002 • 40 citations

Insular cortex representation of dynamic mechanical allodynia in trigeminal neuropathic rats

2008 • 35 citations

Successful inhibition of excitotoxic neuronal damage and microglial activation after delayed application of interleukin‐1 receptor antagonist

2008 • 33 citations

Distribution and morphology of spinothalamic tract neurons in the rat

1997 • 33 citations

Immunological priming potentiates non-viral anti-inflammatory gene therapy treatment of neuropathic pain

2009 • 32 citations

Selective inhibitory effects of pregabalin on peripheral C but not A-delta fibers mediated nociception in intact and spinalized rats

2009 • 27 citations

Direct sensorimotor corticospinal modulation of dorsal horn neuronal C-fiber responses in the rat

2010 • 26 citations

Long-lasting descending and transitory short-term spinal controls on deep spinal dorsal horn nociceptive-specific neurons in response to persistent nociception

2007 • 24 citations

Transient attenuation of neuropathic manifestations in rats following lesion or reversible block of the lateral thalamic somatosensory nuclei

2005 • 22 citations

Excitotoxins as Tools for Producing Brain Lesions

1991 • 19 citations

In Vivo Electrophysiology of Dorsal-Horn Neurons

2004 • 13 citations

Origin of thalamically projecting somatosensory relay neurons in the immature rat

1989 • 12 citations