The membranous skeleton: the role of cell condensations in vertebrate skeletogenesis

Size and shape in ontogeny and phylogeny

1979 • 1,569 citations

Silicone Rubber Substrata: A New Wrinkle in the Study of Cell Locomotion

1980 • 1,333 citations

The proximo‐distal sequence of origin of the parts of the chick wing and the role of the ectoderm

1948 • 1,101 citations

Reconstruction of Tissues by Dissociated Cells

1963 • 1,083 citations

Tenascin: an extracellular matrix protein involved in tissue interactions during fetal development and oncogenesis

1986 • 989 citations

Fibroblast traction as a mechanism for collagen morphogenesis

1981 • 862 citations

Role of transforming growth factor-beta in the development of the mouse embryo.

1987 • 760 citations

Evolutionary Developmental Biology

2021 • 701 citations

Spatial organization of the epithelium and the role of neural crest cells in the initiation of the mammalian tooth germ

1988 • 659 citations

Involvement of Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouse

1991 • 646 citations

Cell Adhesion Molecules in the Regulation of Animal Form and Tissue Pattern

1986 • 630 citations

Stage-related capacity for limb chondrogenesis in cell culture

1977 • 616 citations

Tenascin: An Extracellular Matrix Protein Prominent in Specialized Embryonic Tissues and Tumors

1989 • 604 citations

A Morphogenetic Approach to the Origin and Basic Organization of the Tetrapod Limb

1986 • 604 citations

A MODEL FOR DEVELOPMENT AND EVOLUTION OF COMPLEX MORPHOLOGICAL STRUCTURES

1991 • 589 citations

Connective tissue morphogenesis by fibroblast traction

1982 • 586 citations

The histogenesis of cartilage and bone in the long bones of the embryonic fowl

1925 • 398 citations

Transforming growth factor-beta 1: histochemical localization with antibodies to different epitopes.

1989 • 378 citations

Tenascin is associated with chondrogenic and osteogenic differentiation in vivo and promotes chondrogenesis in vitro.

1987 • 367 citations

Hyaluronate production and removal during corneal development in the chick

1971 • 356 citations

Specific spatial and temporal distribution of retinoic acid receptor gamma transcripts during mouse embryogenesis

1990 • 351 citations

DEVELOPMENT AND EVOLUTIONARY ORIGINS OF VERTEBRATE SKELETOGENIC AND ODONTOGENIC TISSUES

1990 • 324 citations

Homeobox gene expression correlated with the bifurcation process of limb cartilage development

1991 • 317 citations

CHONDROGENESIS, STUDIED WITH THE ELECTRON MICROSCOPE

1960 • 297 citations

The extended family of proteoglycans: social residents of the pericellular zone

1989 • 297 citations

An analysis of the condensation process during chondrogenesis in the embryonic chick hind limb

1975 • 288 citations

Limb development in mouse embryos. I. Analysis of teratogenic effects of retinoic acid

1973 • 287 citations

Epithelial-mesenchymal interactions in development

1983 • 287 citations

Peanut agglutinin and chondroitin-6-sulfate are molecular markers for tissues that act as barriers to axon advance in the avian embryo

1991 • 260 citations

Developmental analysis of the retinoic acid-inducible RAR-βJ2 promoter in transgenic animals

1991 • 258 citations

The distribution of tenascin coincides with pathways of neural crest cell migration

1988 • 258 citations

The development of the vertebrate limb

1980 • 254 citations

‘Generic’ physical mechanisms of morphogenesis and pattern formation

1990 • 254 citations

Topobiology: An Introduction To Molecular Embryology

1988 • 244 citations

EVOLUTION AND MORPHOGENETIC RULES: THE SHAPE OF THE VERTEBRATE LIMB IN ONTOGENY AND PHYLOGENY

1988 • 239 citations

Collagen gene expression during limb cartilage differentiation.

1986 • 238 citations

Experiments on the development in vitro of the avian knee-joint

1934 • 231 citations

Role of transforming growth factor-β in chondrogenic pattern formation in the embryonic limb: Stimulation of mesenchymal condensation and fibronectin gene expression by exogenenous TGF-β and evidence for endogenous TGF-β-like activity

1991 • 229 citations

Hyaluronate in Morphogenesis: Inhibition of Chondrogenesis In Vitro

1972 • 225 citations

In vitro differentiation of bone and hypertrophic cartilage from periosteal-derived cells*1

1991 • 216 citations

Syndecan from embryonic tooth mesenchyme binds tenascin.

1991 • 214 citations

Developmental and Cellular Skeletal Biology

1978 • 211 citations

The pathology of development : a study of inherited skeletal disorders in animals

1963 • 192 citations

Changes in the distribution of tenascin during tooth development

1987 • 190 citations

Expression of cell-adhesion molecules in embryonic induction. I. Morphogenesis of nestling feathers.

1985 • 179 citations

Localization during development of alternatively spliced forms of cytotactin mRNA by in situ hybridization.

1990 • 179 citations

Changes in rate of cellular proliferation during the differentiation of cartilage and muscle in the mesenchyme of the embryonic chick wing

1970 • 177 citations

Morphology and proliferation during early feather development

1965 • 173 citations

Changes in the expression of collagen genes show two stages in chondrocyte differentiation in vitro

1988 • 169 citations

The effect of cell population density on the developmental fate of reaggregating mouse limb bud mesenchyme

1966 • 167 citations

Promotion of embryonic chick limb cartilage differentiation by transforming growth factor-β

1989 • 166 citations

Pattern formation models and developmental constraints

1989 • 163 citations

An ultrastructural study of early myogenesis in the chick wing bud

1973 • 162 citations

Evolution of the nervous system: Role of ontogenetic mechanisms in the evolution of matching populations

1978 • 157 citations

Changes in the pericellular matrix during differentiation of limb bud mesoderm

1985 • 154 citations

Gene Trees and the Origins of Inbred Strains of Mice

1991 • 151 citations

The mechanism of precartilage mesenchymal condensation: A major role for interaction of the cell surface with the amino-terminal heparin-binding domain of fibronectin

1989 • 150 citations

Interactions between neurites and somite cells: inhibition and stimulation of nerve growth in the chick embryo

1986 • 145 citations

The initiation of limb bud outgrowth in the embryonic chick

1971 • 143 citations

Ultrastructural aspects of early development of the fore-limb buds in the chick and the mouse

1965 • 141 citations

CELLULAR DIFFERENTIATION IN SKELETAL TISSUES

1970 • 141 citations

New Aspects of Stroma-Parenchyma Relations in Mammary Gland Differentiation

1991 • 140 citations

DEVELOPMENTAL MECHANISMS UNDERLYING THE FORMATION OF ATAVISMS

1984 • 135 citations

Ontogeny of the limb skeleton in Alligator mississippiensis: Developmental invariance and change in the evolution of archosaur limbs

1990 • 130 citations

Generation of spatially periodic patterns by a mechanical instability: a mechanical alternative to the Turing model

1984 • 127 citations

Congenital hydrocephalus in the mouse, a case of spurious pleiotropism

1943 • 124 citations

The Anatomy and Development of Brachypodism in the Mouse

1973 • 120 citations

A tissue culture analysis of the steps in limb chondrogenesis

1978 • 118 citations

Developmental processes underlying heterochrony as an evolutionary mechanism

1984 • 116 citations

Mesenchymal condensation and cell contact in early morphogenesis of the chick limb

1972 • 104 citations

The detection of a precartilage, blastema-specific marker

1987 • 103 citations

Cell Density and Cell Division in the Early Morphogenesis of the Chick Wing

1972 • 102 citations

Developmental expression of syndecan, an integral membrane proteoglycan, correlates with cell differentiation

1991 • 99 citations

Development and specialization of skeletal muscle

1980 • 99 citations

Cartilage proteoglycan core protein gene expression during limb cartilage differentiation

1986 • 96 citations

Expression of cell adhesion molecules during embryonic induction

1987 • 94 citations

Gap junctional communication during limb cartilage differentiation

1991 • 94 citations

The perinotochordal mesenchyme acts as a barrier to axon advance in the chick embryo: Implications for a general mechanism of axonal guidance

1990 • 92 citations

Regulation of alkaline phosphatase and alpha2(I) procollagen synthesis during early intramembranous bone formation in the rat mandible

1990 • 90 citations

Hyaluronate-cell interactions during differentiation of chick embryo limb mesoderm

1987 • 90 citations

Allophenic mice of multi-embryo origin.

1971 • 90 citations

Fibronectin gene expression during limb cartilage differentiation

1989 • 87 citations

Clonal origins of somites and their muscle derivatives: Evidence from allophenic mice

1972 • 86 citations

The role of cell migration in the development of the embryonic chick limb bud

1967 • 86 citations

Quantitation of type II procollagen mRNA levels during chick limb cartilage differentiation

1985 • 85 citations

Limb development in the polydactylous talpid3 mutant of the fowl

1967 • 82 citations

Genetical studies on the skeleton of the mouse

1953 • 81 citations

Lineage and pattern in the developing vertebrate limb

1988 • 79 citations

Temporal and spatial analysis of cartilage proteoglycan core protein gene expression during limb development by in situ hybridization

1988 • 78 citations

The skeleton of the eye

1962 • 78 citations

Cell adhesion and movement in relation to the developing limb pattern in normal and talpid mutant chick embryos.

1968 • 76 citations

The developmental effects of congenital hydrocephalus (ch) in the mouse

1970 • 70 citations

Precision of Development in Chick Limb Morphogenesis

1973 • 69 citations

Genetic inhibition of mesenchymal cell death and the development of form and skeletal pattern in the limbs oftalpid3(ta3) mutant chick embryos

1974 • 68 citations

Intramembranous osteogenesis and angiogenesis in the chick embryo.

1989 • 67 citations

Interdigital tissue chondrogenesis induced by surgical removal of the ectoderm in the embryonic chick leg bud.

1986 • 66 citations

Developmental abnormalities in the trunk and limbs of the talpid3 mutant of the fowl

1964 • 66 citations

Cell sorting and chondrogenic aggregate formation in micromass culture

1987 • 65 citations

Alterations of lectin binding during chondrogenesis of mouse limb buds

1984 • 64 citations

The mechanism of cellular orientation during early cartilage formation in the chick limb and regenerating amphibian limb

1974 • 62 citations

Experimental analysis of the in vivo chondrogenic potential of the interdigital mesenchyme of the chick leg bud subjected to local ectodermal removal

1989 • 62 citations

An analysis of feather germ formation in the embryo and in vitro, in normal development and in skin treated with hydrocortisone

1972 • 61 citations

Aspects of limb morphogenesis in mammals

1965 • 60 citations

Developmental abnormalities in the head region of the talpid3 mutant of the fowl

1964 • 57 citations

The Chondroblast and the Chondrocyte

1983 • 56 citations

The extracellular matrix architecture relating to myotendinous pattern formation in the distal part of the developing chick limb: An ultrastructural, histochemical and immunocytochemical analysis

1989 • 55 citations

Assembly and disassembly of gap junctions during mesenchymal cell condensation and early chondrogenesis in limb buds of mouse embryos.

1984 • 54 citations

Monoclonal antibody to chick embryo hyaluronan-binding protein: Changes in distribution of binding protein during early brain development

1991 • 50 citations

Cartilage. Vol. 2. Development, Differentiation and Growth

1984 • 50 citations

The timing of the onset of osteogenesis in the tibia of the embryonic chick

1979 • 50 citations

The Ectomesenchymal-endodermal Interaction System (EEIS) of Triturus alpestris in Tissue Culture

1975 • 50 citations

Allometry formula: a cellular model.

1980 • 50 citations

Cell movement and adhesion in the developing chick wing bud: studies on cultured mesenchyme cells from normal and Talpid3 mutant embryos

1975 • 48 citations

Identification and distribution of gap junctions in the mesoderm of the developing chick limb bud

1978 • 47 citations

Molecular changes during determination and differentiation of the dental mesenchymal cell lineage.

1990 • 46 citations

Biological Sciences: Numerology of Development

1972 • 46 citations

Specificity in the differentiation and morphogenesis of neural crest-derived scleral ossicles and of epithelial scleral papillae in the eye of the embryonic chick

1981 • 46 citations

Immunohistochemical localization of the matrix glycoprotein tenascin in the skull of the growing rat

1988 • 44 citations

The Ectomesenchymal-Endodermal Interaction-System (EEIS) of Triturus alpestris in Tissue Culture

1974 • 44 citations

The binding pattern of peanut lectin associated with sclerotome migration and the formation of the vertebral axis in the chick embryo

1989 • 44 citations

Control of somite number in normal and amputated mutant mouse embryos: an experimental and a theoretical analysis

1978 • 42 citations

The Developmental Mechanics and Potencies of the Undifferentiated Mesenchyme of the Mandible

1941 • 41 citations

Expression of tenascin in response to neural induction in amphibian embryos

1988 • 40 citations

Cell-cell interaction by mouse limb cells during in vitro chondrogenesis: Analysis of the brachypod mutation

1982 • 39 citations

Transient expression of a chondroitin sulfate-related epitope during cartilage histomorphogenesis in the axial skeleton of fetal rats

1989 • 38 citations

The development of the conjunctival papillae and of the scleral bones in the embryo chick.

1943 • 38 citations

Type IX Collagen Gene Expression During Limb Cartilage Differentiation

1991 • 37 citations

A re-examination of two skeletal mutants of the mouse, vestigial-tail (rt) and congenital hydrocephalus (ch)

1974 • 37 citations

Intercellular adhesion and formation of aggregates in normal and Talpid3 Mutant chick limb mesenchyme

1975 • 36 citations

The Genetics of the Skeleton

1989 • 36 citations

Differentiative ability of the tibial periosteum from the embryonic chick

1980 • 36 citations

Traction and the formation of mesenchymal condensations in vivo

1990 • 35 citations

An embryological analysis of two mutants in the house mouse, both producing cleft palate

1957 • 35 citations

Effects of growth factors on the differentiation of neural crest cells and neural crest cell-derivatives.

1991 • 34 citations

Muscle and cartilage differentiation in small and large explants from the chick embryo limb bud

1974 • 34 citations

Clonal model of vertebral column and skull development derived from genetically mosaic skeletons in allophenic mice

1972 • 33 citations

An analysis of the development of conjunctival papillae and scleral ossicles in the eye of the scaleless mutant,

1970 • 33 citations

Avian scale development

1982 • 33 citations

Cytotoxic effects of 6‐mercaptopurine on the limb‐bud blastemal cells of rat embryos

1975 • 33 citations

Evidence for regulation of growth, size and pattern in the developing chick limb bud

1981 • 32 citations

Cell commitment and differentiation

1987 • 32 citations

Toward an understanding of the epithelial requirement for osteogenesis in scleral mesenchyme of the embryonic chick

1991 • 31 citations

Stimulation of limb cartilage differentiation by cyclic AMP is dependent on cell density

1989 • 31 citations

Reactivity of normal and brachypod mouse limb mesenchymal cells with con A

1976 • 31 citations

Chimaeras and Cell Lineage in Development

1972 • 30 citations

Effect of the brachypod mutation on cell adhesion and chondrogenesis in aggregates of mouse limb mesenchyme

1977 • 30 citations

Histochemical aspects of the differentiation of adventitious cartilage on the membrane bones of the embryo chick

1968 • 30 citations

Control of form and pattern in the vertebrate limb.

1971 • 30 citations

Cell adhesion and chondrogenesis in brachypod mouse limb mesenchyme: fragment fusion studies

1978 • 29 citations

Lectin binding sites in developing mouse limb buds

1991 • 29 citations

The sequential expression of tenascin mRNA in epithelium and mesenchyme during feather morphogenesis

1991 • 29 citations

Correcting the Phenotype of the Epidermis from Chick Embryos Homozygous for the Gene Scaleless ( sc / sc )

1981 • 28 citations

Cell contact and surface coat alterations of limb-bud mesenchymal cells during differentiation

1982 • 27 citations

The origin of the ectomesenchymal condensations which precede the development of the bony scleral ossicles in the eyes of embryonic chicks.

1983 • 26 citations

How is mandibular growth controlled during development and evolution?

1982 • 26 citations

Suppression of morphogenesis in embryonic mouse limbs exposed in vitro to excess gravity

1983 • 25 citations

Lectin binding pattern in the embryonal and early fetal human vertebral column

1991 • 25 citations

Patterns of cell division, cell death and chondrogenesis in cultured aggregates of normal and talpid3 mutant chick limb mesenchyme cells

1972 • 25 citations

Mandibular morphogenesis and craniofacial malformations.

1982 • 24 citations

In vitrochondrogenesis of limb mesoderm from normal and brachypod mouse embryos

1975 • 23 citations

Syndecan and tenascin: Induction during early tooth morphogenesis and possible interactions

1990 • 23 citations

Newer Knowledge of Chondrogenesis

1973 • 22 citations

Genetics and morphology of a recessive mutation in the house mouse affecting head and limb skeleton

1956 • 22 citations

The role of tissue interactions in the growth of bone.

1982 • 22 citations

A freeze-fracture and morphometric analysis of gap junctions of limb bud cells: initial studies on a possible mechanism for morphogenetic signalling during development.

1983 • 21 citations

Aberrant metabolism of matrix components in neonatal fibular cartilage of brachypod (bpH) mice

1975 • 20 citations

Changes in mesenchymal cell-shape, matrix collagen and tenascin accompany bud formation in the early chick lung

1991 • 20 citations

Alkaline phosphatase activity in fetal hind limbs of the mouse mutation brachypodism

1973 • 18 citations

A scanning electron microscopic study of the developing epithelial scleral papillae in the eye of the embryonic chick

1981 • 18 citations

Abnormalities in bone and cartilage development in thetalpid3mutant of the fowl

1968 • 18 citations

Reciprocal interactions between epithelium, mesenchyme, and epidermal growth factor (EGF) in the regulation of mandibular mitotic activity in the embryonic chick.

1990 • 18 citations

Development of chick embryo conjunctival papillae and scleral ossicles after hydrocortisone treatment

1973 • 17 citations

Alterations in cell surface galactosyltransferase activity during limb chondrogenesis in brachypod mutant mouse embryos

1988 • 16 citations

Spatial and temporal changes in the pattern of glycosylation of the developing chick limb tissue components as revealed by fluorescent conjugated lectin probes

1988 • 15 citations

Changes in the types of collagen synthesized during chondrogenesis of the mouse otic capsule

1987 • 14 citations

Epidermal Papillæ and Dermal Bones of the Chick Sclerotic

1941 • 14 citations

Feather morphogenesis and feather pattern in normal and talpid 3 mutant chick embryos

1971 • 14 citations

Acidic glycosaminoglycans in developing sterno-costal cartilage of the hydrocephalic (ch+/ch+) mouse

1973 • 13 citations

Accelerated maturation of limb mesenchyme by the BrachypodH mouse mutation

1983 • 12 citations

An analysis of chick limb bud intercellular adhesion underlying the establishment of cartilage aggregates in suspension culture

1990 • 12 citations

The initial expression and patterned appearance of tenascin in scutate scales is absent from the dermis of the scaleless (sc/sc) chicken

1991 • 12 citations

Mitotic Activity during the Early Differentiation of the Scleral Bones in the Chick

1956 • 10 citations

Differentiation of Musculoskeletal Tissues

1989 • 7 citations

Mesodermal Cell Deaths during the Early Development of the Scleral Bones in the Chick

1956 • 6 citations

Three distinct molecular species of proteoglycan synthesized by the rat limb bud at the prechondrogenic stage

1989 • 6 citations

Matrix-driven translocation: possible role in precartilage mesenchymal condensation.

1986 • 4 citations

[Morphological, histochemical and autoradiographic study of skeletogenesis in the developing limbs of the mouse embryo. I. Forelimbs].

1978 • 4 citations

Cell generation times in normal and talpid3 mutant chick limb mesenchyme.

1989 • 2 citations

The involvement of microfilaments and microtubules in the lateral mobility of lectin binding sites of normal and brachypod mouse limb mesenchyme

1978 • 1 citations