The Chondroblast and the Chondrocyte

A series of normal stages in the development of the chick embryo

1951 • 12,226 citations

Fibronectins—adhesive glycoproteins of cell surface and blood

1978 • 1,418 citations

Epithelial-Mesenchymal Interactions

1967 • 1,218 citations

The proximo‐distal sequence of origin of the parts of the chick wing and the role of the ectoderm

1948 • 1,101 citations

Structurally Distinct Collagen Types

1980 • 1,078 citations

Cell biology of extracellular matrix

1992 • 1,042 citations

Positional Information in Chick Limb Morphogenesis

1973 • 718 citations

Stage-related capacity for limb chondrogenesis in cell culture

1977 • 616 citations

Vertebrate Limb and Somite Morphogenesis

1979 • 613 citations

Limb-somite relationship: origin of the limb musculature

1977 • 528 citations

Experimental analysis of the origin of the wing musculature in avian embryos

1977 • 520 citations

Biochemical characteristics and biological significance of the genetically-distinct collagens

1976 • 468 citations

Collagen: Molecular Diversity in the Body's Protein Scaffold

1980 • 448 citations

Study of differential collagen synthesis during development of the chick embryo by immunofluorescence

1976 • 402 citations

A quantitative analysis of the effect of excision of the AER from the chick limb-bud

1974 • 376 citations

Changes in type of collagen synthesized as clones of chick chondrocytes grow and eventually lose division capacity.

1976 • 355 citations

Physicochemical characterization and molecular organization of the collagen A and B chains

1978 • 347 citations

CHICK CARTILAGE COLLAGEN: A NEW TYPE OF α1 CHAIN NOT PRESENT IN BONE OR SKIN OF THE SPECIES

1969 • 329 citations

Collagen heterogeneity in human cartilage: Identification of several new collagen chains

1979 • 324 citations

Clonal stability and phenotypic expression of chick cartilage cells in vitro.

1966 • 322 citations

Interaction of cartilage proteoglycans with hyaluronic acid

1977 • 303 citations

CHONDROGENESIS, STUDIED WITH THE ELECTRON MICROSCOPE

1960 • 297 citations

Extracellular Matrix Influences on Gene Expression

1975 • 297 citations

Distribution of fibroblast surface antigen in the developing chick embryo.

1975 • 293 citations

An analysis of the condensation process during chondrogenesis in the embryonic chick hind limb

1975 • 288 citations

Changes in the patterns of collagens and fibronectin during limb-bud chondrogenesis

1980 • 264 citations

Hyaluronate turnover during chondrogenesis in the developing chick limb and axial skeleton

1972 • 240 citations

Experiments on the development in vitro of the avian knee-joint

1934 • 231 citations

Hyaluronate in Morphogenesis: Inhibition of Chondrogenesis In Vitro

1972 • 225 citations

Effects of the nicotinamide-sensitive teratogen 3-acetylpyridine on chick limb cells in culture

1970 • 221 citations

THE LOSS OF PHENOTYPIC TRAITS BY DIFFERENTIATED CELLS

1966 • 219 citations

Synthesis and extracellular deposition of fibronectin in chondrocyte cultures. Response to the removal of extracellular cartilage matrix.

1978 • 219 citations

Characterization of bovine aorta proteoglycan extracted with guanidine hydrochloride in the presence of protease inhibitors.

1979 • 207 citations

GLYCOSAMINOGLYCAN SYNTHESIS BY EMBRYONIC INDUCTORS: NEURAL TUBE, NOTOCHORD, AND LENS

1974 • 206 citations

STUDIES ON ULTRASTRUCTURAL IDENTIFICATION AND DISTRIBUTION OF PROTEIN-POLYSACCHARIDE IN CARTILAGE MATRIX

1967 • 195 citations

Stimulation of Chondromucoprotein Synthesis in Chondrocytes by Extracellular Chondromucoprotein

1972 • 194 citations

Temporal and spatial transitions in collagen types during embryonic chick limb development

1973 • 186 citations

Environmental enhancement of in vitro chondrogenesis

1973 • 178 citations

Fibronectin alters the phenotypic properties of cultured chick embryo chondroblasts

1979 • 177 citations

Changes in rate of cellular proliferation during the differentiation of cartilage and muscle in the mesenchyme of the embryonic chick wing

1970 • 177 citations

The control of muscle and cartilage development in the chick limb: the role of differential vascularization

1973 • 176 citations

The effect of cell population density on the developmental fate of reaggregating mouse limb bud mesenchyme

1966 • 167 citations

Isolation and characterization of proteoglycans from chick limb bud chondrocytes grown in vitro.

1976 • 162 citations

An ultrastructural study of early myogenesis in the chick wing bud

1973 • 162 citations

An autoradiographic study of the uptake of S35-sulfate during the differentiation of limb bud cartilage

1965 • 160 citations

Immunofluorescent localization of collagen types I, II, and III in the embryonic chick eye

1977 • 159 citations

Identification and change of collagen types in differentiating myoblasts and developing chick muscle

1979 • 159 citations

Inhibition of limb chondrogenesis in vitro by vitamin A: Alterations in cell surface characteristics

1978 • 159 citations

Stimulation of in vitro somite chondrogenesis by procollagen and collagen

1975 • 158 citations

A description of chick wing bud development and a model of limb morphogenesis

1973 • 155 citations

The influence of an adhesive cell surface protein on chondrogenic expression in vitro

1979 • 155 citations

Limb Morphogenesis

1961 • 154 citations

Chemical and physical changes in proteoglycans during development of chick limb bud chondrocytes grown in vitro.

1977 • 152 citations

Synthesis and localization of fibronectin during collagenous matrix-mesenchymal cell interaction and differentiation of cartilage and bone in vivo.

1980 • 150 citations

Immunological and biochemical studies of collagen type transition during in vitro chondrogenesis of chick limb mesodermal cells

1977 • 147 citations

The influence of epithelia on cartilage and loose connective tissue formation by limb mesenchyme cultures

1981 • 143 citations

Chapter 9 Immunological Studies on Collagen Type Transition in Chondrogenesis

1980 • 142 citations

Vitreous body collagen. Evidence for a dual origin from the neural retina and hyalocytes.

1976 • 142 citations

The Synthesis of Collagen and Glycosaminoglycans by Dedifferentiated Chondroblasts in Culture

1973 • 139 citations

THE FINE STRUCTURE OF BOVINE NASAL CARTILAGE

1971 • 138 citations

TRANSFORMATION‐SENSITIVE CELL SURFACE PROTEIN: ISOLATION, CHARACTERIZATION, AND ROLE IN CELLULAR MORPHOLOGY AND ADHESION

1978 • 136 citations

Synthesis of two collagen types by embryonic chick corneal epithelium in vitro.

1977 • 134 citations

Differentiation in vitro: Effects of Sephadex Fractions of Chick Embryo Extract

1966 • 130 citations

Sulfated mucopolysaccharide synthesis during the development of Rana pipiens

1973 • 124 citations

The stabilization of cartilage properties in the cartilage‐forming mesenchyme of the embryonic chick limb

1969 • 122 citations

Nonuniform distribution of fibronectin during avian limb development

1982 • 122 citations

Notochordal stimulation of in vitro somite chondrogenesis before and after enzymatic removal of perinotochordal materials

1975 • 121 citations

The Anatomy and Development of Brachypodism in the Mouse

1973 • 120 citations

A tissue culture analysis of the steps in limb chondrogenesis

1978 • 118 citations

Differences among sulfated proteoglycans synthesized in nonchondrogenic cells, presumptive chondroblasts, and chondroblasts.

1976 • 117 citations

The inhibition of sulphate incorporation in isolated adult chondrocytes by hyaluronic acid

1973 • 116 citations

Inhibition of proteoglycan biosynthesis by hyaluronic acid in chondrocytes in cell culture

1976 • 116 citations

Somite chondrogenesis in vitro

1978 • 115 citations

In vitro studies on the morphogenesis and differentiation of the mesoderm subjacent to the apical ectodermal ridge of the embryonic chick limb-bud

1979 • 115 citations

Depression by hyaluronic acid of glycosaminoglycan synthesis by cultured chick embryo chondrocytes

1974 • 115 citations

The Irreversible Inhibition of Differentiation of Limb-Bud Mesenchyme by Bromodeoxyuridine

1972 • 114 citations

The spatial distribution of hyaluronic acid and mesenchymal condensation in the embryonic chick wing

1981 • 112 citations

Immunochemical and biochemical study of collagen synthesis by chondrocytes in culture

1977 • 111 citations

Myogenic and chondrogenic lineages in developing limb buds grown in vitro

1974 • 109 citations

Cell death and the development of limb form and skeletal pattern in normal andwingless(ws) chick embryos

1973 • 106 citations

Morphogenetic Phases in Development

1968 • 102 citations

Cell Density and Cell Division in the Early Morphogenesis of the Chick Wing

1972 • 102 citations

An ultrastructural study of early chondrogenesis in the chick wing bud

1972 • 102 citations

The collagen of chick embryonic notochord

1973 • 101 citations

Synthesis of Proteochondroitin Sulfate by Normal, Nanomelic, and 5-Bromodeoxyuridine-Treated Chondrocytes in Cell Culture

1972 • 99 citations

Chapter 4 Concepts and Mechanisms of Cartilage Differentiation

1974 • 97 citations

Interaction between limb bud ectoderm and mesoderm in the chick embryo. II. Experimental limb duplication

1956 • 96 citations

Proteochondroitin sulfate synthesis and chondrogenic expression

1974 • 93 citations

Stage- and position-related changes in chondrogenic response of chick embryonic wing mesenchyme to treatment with dibutyryl cyclic AMP

1981 • 93 citations

Temporal and spatial distribution of fibronectin during development of the embryonic chick limb bud

1982 • 93 citations

Chondrogenesis of the Somitic Mesoderm

1977 • 89 citations

Levels of genetic control in development

1982 • 87 citations

The role of cell migration in the development of the embryonic chick limb bud

1967 • 86 citations

Chondrogenesis and cell proliferation in limb bud cell cultures treated with cytosine arabinoside and vitamin A

1978 • 84 citations

Synthesis of type II collagen in vitro by embryonic chick neural retina tissue.

1976 • 83 citations

The distal boundary of myogenic primordia in chimeric avian limb buds and its relation to an accessible population of cartilage progenitor cells

1981 • 80 citations

Stimulation of Chondroitin Sulfate Proteoglycan Production by Chondrocytes in Monolayer

1975 • 80 citations

Position-related capacity for differentiation of limb mesenchyme in cell culture

1979 • 78 citations

Biochemical and ultrastructural studies of collagen and proteochondroitin sulfate in normal and nanomelic cartilage

1976 • 75 citations

Control of Chondrogenesis in Limb-Bud Cell Cultures by Bromodeoxyuridine

1973 • 75 citations

Isolation of proteoglycan-hyaluronate complexes from bovine aorta.

1979 • 72 citations

The stability of the collagen phenotype during stimulated collagen, glycosaminoglycan, and DNA synthesis by articular cartilage organ cultures

1979 • 71 citations

SOMITE CHONDROGENESIS

1973 • 71 citations

Formation of cartilage by non-chondrogenic cell types

1978 • 70 citations

An in vitro Analogue of Early Chick Limb Bud Outgrowth

1976 • 67 citations

A gradation of hyaluronate accumulation along the proximodistal axis of the embryonic chick limb bud.

1981 • 66 citations

The link proteins as specific components of cartilage proteoglycan aggregates in vivo. Associative extraction of proteoglycan aggregate from swarm rat chondrosarcoma

1979 • 65 citations

Analysis of cartilage differentiation from skeletal muscle grown on bone matrix

1980 • 64 citations

Studies on the possible role of cyclic AMP in limb morphogenesis and differentiation

1980 • 64 citations

Etude de la migration des cellules somitiques dans le m�soderme somatopleural de l'�bauche de l'aile

1978 • 63 citations

Inductive activity and enduring cellular constitution of a supernumerary apical ectodermal ridge grafted to the limb bud of the chick embryo

1976 • 63 citations

Characterization of notochord collagen as a cartilage-type collagen

1974 • 62 citations

Ultrastructural histochemical and autoradiographic studies on the developing chick notochord

1972 • 59 citations

Chondrogenesis: Genotypic and phenotypic expression

1968 • 58 citations

The effect of embryo extract on the types of collagen synthesized by cultured chick chondrocytes

1976 • 56 citations

Simultaneous localization of type II collagen and core protein of chondroitin sulfate proteoglycan in individual chondrocytes.

1979 • 56 citations

Cyclic AMP derivatives stimulate the chondrogenic differentiation of the mesoderm subjacent to the apical ectodermal ridge of the chick limb bud

1979 • 56 citations

Spatiotemporal patterns of fibronectin distribution during embryonic development I. Chick limbs

1981 • 54 citations

EFFECT OF EXTRACELLULAR CHONDROITIN SULFATE ON CULTURED CHONDROCYTES

1974 • 52 citations

Embryonic neural retina collagen: In vitro synthesis of high molecular weight forms of type II plus a new genetic type

1978 • 52 citations

A radioimmune study of the effect of bromodeoxyuridine on the synthesis of proteoglycan by differentiating limb bud cultures

1977 • 52 citations

The occurrence of a new type of proteochondroitin sulfate in the developing chick embryo

1976 • 51 citations

Inhibition of “spontaneous,” notochord-induced, and collagen-induced in vitro somite chondrogenesis by cyclic AMP derivatives and theophylline

1976 • 49 citations

The effects of the nicotinamide sensitive teratogen 3‐acetylpyridine on chick limb mesodermal cells in culture: Biochemical parameters

1972 • 48 citations

THE IDENTIFICATION OF A SULFATED MUCOPOLYSACCHARIDE IN CHICK EMBRYOS, STAGES 11-23

1963 • 47 citations

A gradation of hyaluronate accumulation along the proximodistal axis of the embryonic chick limb bud

1981 • 45 citations

Morphological and biochemical differentiation of limb bud cells cultured in chemically defined medium

1979 • 45 citations

CHANGES IN CELL SURFACE PROTEINS DURING NORMAL AND VITAMIN A‐INHIBITED CHONDROGENESIS IN VITRO

1978 • 44 citations

Synthesis of proteoglycans by suspension and monolayer cultures of adult chondrocytes and de novo cartilage nodules-the effect of hyaluronic acid

1977 • 44 citations

Migration of somitic cells into the somatopleural mesoderm of the limb anlage

1978 • 43 citations

An immunohistochemical study of extracellular matrix formation during chondrogenesis

1978 • 42 citations

Cartilage formation from so-called myogenic tissue of chick embryo limb buds.

1966 • 41 citations

THE STRUCTURE OF CARTILAGE PROTEOGLYCANS

1975 • 40 citations

Heterogeneity of proteoglycans in developing chick limb cartilage

1977 • 40 citations

Monomeric and aggregate proteoglycans in the chondrogenic differentiation of embryonic chick limb buds

1979 • 39 citations

Immunochemical and biochemical study of collagen synthesis by chondrocytes in culture

1977 • 38 citations

Glycosaminoglycan synthesis by the apical ectodermal ridge of chick limb bud

1981 • 38 citations

Physical and immunochemical characterization of proteoglycans synthesized during chondrogenesis in the chick embryo.

1980 • 38 citations

Isolation of Mucopolysaccharide from the Precartilaginous Embryonic Chick Limb Bud.

1965 • 38 citations

A comparison of the proteoglycans synthesized in Meckel's and sternal cartilage from normal and nanomelic chick embryos

1979 • 36 citations

Analysis of cartilage differentiation from skeletal muscle grown on bone matrix

1980 • 35 citations

Antibody binding of cartilage-specific proteoglycans

1980 • 34 citations

The ubiquitous occurrence of chondroitin sulfates in chick embryos

1975 • 31 citations

Has collagen a role in muscle pattern formation in the developing chick wing? 1. An immunofluorescence study.

1980 • 31 citations

Effect of the brachypod mutation on cell adhesion and chondrogenesis in aggregates of mouse limb mesenchyme

1977 • 30 citations

Electron microscopic studies on developing cartilage. I. The membrane system related to the synthesis and secretion of extracellular materials.

1970 • 29 citations

Cell adhesion and chondrogenesis in brachypod mouse limb mesenchyme: fragment fusion studies

1978 • 29 citations

Effect of 5-bromodeoxyuridine on ultrastructure of developing limb-bud cells in vitro

1975 • 29 citations

Molecular sieve chromatography of proteoglycans: A comparative analysis

1976 • 27 citations

Analysis of glycosaminoglycans during chondrogenesis of normal and brachypod mouse limb mesenchyme

1980 • 26 citations

Modulation of Extracellular Matrix Production by Conditioned Medium

1973 • 24 citations

In vitrochondrogenesis of limb mesoderm from normal and brachypod mouse embryos

1975 • 23 citations

Newer Knowledge of Chondrogenesis

1973 • 22 citations

The lack of an inhibitory effect of hyaluronate on chondrogenesis in chick limb-bud mesoderm cells grown in culture

1978 • 18 citations

In Vitro Study of Cartilage Induction in T/TMice

1958 • 17 citations

Scrutinizing Vietnam's Progress Towards Gender Equality

2010 • 15 citations

Changes in endogenous cell surface galactosyltransferase activity during in vitro limb bud chondrogenesis

1982 • 15 citations

Muscle-forming potential of the non-somitic cells of the early avian limb bud

1979 • 12 citations

The effect of collagen on the cyclic AMP content of embryonic somites

1979 • 10 citations

Sulfated proteoglycan accumulation during development of the embryonic chick limb bud studied by electron microscopic autoradiography

1980 • 8 citations

Reversible inhibition of chondrogenic expression by certain hyaluronidase preparations

1979 • 5 citations

Deleted Work

1955 • 0 citations