Prevalence of amplification of the oncogenes c-myc, HER2/neu, and int-2 in one thousand human breast tumours: Correlation with steroid receptors

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

The neu oncogene encodes an epidermal growth factor receptor-related protein

1986 • 1,131 citations

Basic methods in molecular biology

1987 • 842 citations

The neu Gene: an erb B-Homologous Gene Distinct from and Unlinked to the Gene Encoding the EGF Receptor

1985 • 513 citations

Genetic alteration of the c-myc protooncogene (MYC) in human primary breast carcinomas.

1986 • 413 citations

Alterations to either c-erbB-2(neu) or c-myc proto-oncogenes in breast carcinomas correlate with poor short-term prognosis.

1987 • 360 citations

Correlation between long-term survival in breast cancer patients and amplification of two putative oncogene-coamplification units: hst-1/int-2 and c-erbB-2/ear-1.

1989 • 321 citations

Follow-up study of HER-2/neu amplification in primary breast cancer.

1991 • 268 citations

Prognostic value of receptors for insulin-like growth factor 1, somatostatin, and epidermal growth factor in human breast cancer.

1989 • 217 citations

Amplification of the int-2 gene in primary human breast tumors.

1988 • 172 citations

Proto-oncogene amplification and human breast tumor phenotype

1990 • 154 citations

Proto-oncogene abnormalities in human breast cancer: correlations with anatomic features and clinical course of disease.

1987 • 143 citations

Amplification of FGF-related genes in human tumors: possible involvement of HST in breast carcinomas.

1989 • 134 citations

4. The role of the epidermal growth factor receptor and the c-erbB-2 protein in breast cancer

1990 • 130 citations

Genetic alterations of c-myc, c-erbB-2, and c-Ha-ras protooncogenes and clinical associations in human breast carcinomas.

1989 • 125 citations

Amplification of human int-2 in breast cancers and squamous carcinomas.

1988 • 125 citations

Association of INT2/HST1 coamplification in primary breast cancer with hormone-dependent phenotype and poor prognosis

1991 • 124 citations

The neu (c-erbB-2) oncogene.

1989 • 120 citations

Cathepsin D assay in primary breast cancer and lymph nodes: Relationship with c-myc, c-erb-B-2 and int-2 oncogene amplification and node invasiveness

1990 • 87 citations

In Vivo Amplification and Rearrangement of c-myc Oncogene in Human Breast Tumors

1988 • 84 citations

c-erbB-2/c-erbA co-amplification indicative of lymph node metastasis, and c-myc amplification of high tumour grade, in human breast carcinoma

1989 • 72 citations

Analysis of the int-1, int-2, c-myc, and neu oncogenes in human breast carcinomas.

1990 • 47 citations

The Enhancing Effect (or Actively Acquired Tolerance) and the Histocompatibility-2 Locus in the Mouse<xref ref-type="fn" rid="fn1">1</xref><xref ref-type="fn" rid="fn2">2</xref>

1954 • 33 citations

3. Role of theINT-genes in murine mammary tumor development and implications for human breast cancer

1990 • 16 citations

A paradigm for oncogene complementation in human breast cancer

1989 • 15 citations

Chapter III. 1. Mutations in human breast cancer cells: Dominantly-acting oncogenes and tumor suppressor genes suggest strategies for targeted interference

1990 • 9 citations

Int‐1 and int‐2: Oncogenic proteins, mitogens and morphogens?

1988 • 4 citations