Signal interactions between nitric oxide and reactive oxygen intermediates in the plant hypersensitive disease resistance response

Superoxide Dismutase

1969 • 12,578 citations

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

The Biology of Oxygen Radicals

1978 • 3,361 citations

THE OXIDATIVE BURST IN PLANT DISEASE RESISTANCE

1997 • 3,171 citations

H2O2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response

1994 • 2,757 citations

A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds

1993 • 2,423 citations

Nitric oxide functions as a signal in plant disease resistance

1998 • 1,829 citations

Reactive Oxygen Intermediates Mediate a Systemic Signal Network in the Establishment of Plant Immunity

1998 • 1,126 citations

Perspectives series: host/pathogen interactions. Mechanisms of nitric oxide-related antimicrobial activity.

1997 • 1,109 citations

Initiation of Runaway Cell Death in an Arabidopsis Mutant by Extracellular Superoxide

1996 • 845 citations

DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite.

1996 • 630 citations

Peroxynitrite‐mediated oxidative protein modifications

1995 • 611 citations

Salicylic acid potentiates an agonist-dependent gain control that amplifies pathogen signals in the activation of defense mechanisms.

1997 • 584 citations

Nitric oxide and oxygen radicals: a question of balance

1995 • 568 citations

Superoxide Dismutase in Plants

1994 • 561 citations

Nitric oxide and cell death

1999 • 443 citations

Mechanisms of nitric oxide-related antimicrobial activity

1997 • 439 citations

Isozymes of superoxide dismutase from wheat germ

1973 • 403 citations

Iron regulates ferritin mRNA translation through a segment of its 5' untranslated region.

1987 • 365 citations

Identification of a novel iron-responsive element in murine and human erythroid delta-aminolevulinic acid synthase mRNA.

1991 • 349 citations

Nitric oxide counteracts cytotoxic processes mediated by reactive oxygen species in plant tissues

1999 • 306 citations

Peroxynitrite-induced Apoptosis in HL-60 Cells

1995 • 300 citations

Peroxynitrite rapidly permeates phospholipid membranes

1997 • 299 citations

Nitric oxide mediates iron release from ferritin

1990 • 290 citations

Plasma Membrane Redox Enzyme Is Involved in the Synthesis of O2- and H2O2 by Phytophthora Elicitor-Stimulated Rose Cells

1995 • 289 citations

Downregulation of Cu/Zn superoxide dismutase leads to cell death via the nitric oxide-peroxynitrite pathway

1996 • 267 citations

An EPR Investigation of the Products of the Reaction of Cytosolic and Mitochondrial Aconitases with Nitric Oxide

1997 • 256 citations

Generation of active oxygen in elicited cells of Arabidopsis thaliana is mediated by a NADPH oxidase‐like enzyme

1996 • 228 citations

Nitric Oxide Modulates the Activity of Tobacco Aconitase

2000 • 211 citations

Use of a New Tetrazolium-Based Assay to Study the Production of Superoxide Radicals by Tobacco Cell Cultures Challenged with Avirulent Zoospores ofPhytophthora parasitica varnicotianae1

1998 • 201 citations

Reaction of nitric oxide with hydrogen peroxide to produce potentially cytotoxic singlet oxygen as a model for nitric oxide‐mediated killing

1993 • 196 citations

Evidence for a Mechanically Induced Oxidative Burst

1995 • 196 citations

Peroxynitrite induces haem oxygenase-1 in vascular endothelial cells: a link to apoptosis

1999 • 194 citations

The Nitric Oxide/Superoxide Assay

1997 • 167 citations

LSD1 Regulates Salicylic Acid Induction of Copper Zinc Superoxide Dismutase in Arabidopsis thaliana

1999 • 166 citations

The Chemistry and Tumoricidal Activity of Nitric Oxide/Hydrogen Peroxide and the Implications to Cell Resistance/Susceptibility

1996 • 162 citations

Characterization of Gmhsp26-A, a Stress Gene Encoding a Divergent Heat Shock Protein of Soybean: Heavy-Metal-Induced Inhibition of Intron Processing

1988 • 144 citations

The Metal-Insulator Transition in Correlated Disordered Systems

1996 • 136 citations

The bifunctional iron-responsive element binding protein/cytosolic aconitase: the role of active-site residues in ligand binding and regulation.

1994 • 134 citations

New disease resistance genes in soybean against Pseudomonas syringae pv glycinea: evidence that one of them interacts with a bacterial elicitor

1991 • 110 citations

Identification of a Plant-Encoded Analog of PKR, the Mammalian Double-Stranded RNA-Dependent Protein Kinase

1995 • 83 citations

The influence of delivery rate on the chemistry and biological effects of nitric oxide

1993 • 76 citations

Soluble superoxide dismutase (SOD) in susceptible and resistant host-parasite complexes of Phaseolus vulgaris and Uromyces phaseoli

1987 • 54 citations

Overexpression of CuZn superoxide dismutase protects RAW 264.7 macrophages against nitric oxide cytotoxicity

1999 • 49 citations

Nitric oxide co-operates with hydrogen peroxide in inducing DNA fragmentation and cell lysis in murine lymphoma cells

1997 • 48 citations

Effect of tobacco mosaic virus infection of levels of soluble superoxide dismutase (SOD) in nicotiana tabacum and nicotiana glutinosa leaves

1986 • 29 citations

Molecular Cloning and Expression Patterns of Cu/Zn-Superoxide Dismutases in Developing Soybean Seeds

1998 • 7 citations