Identification of amino acid residues critical for endonuclease and integration activities of HIV-1 IN protein in Vitro

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1989 • 7,496 citations

Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes.

1985 • 2,450 citations

A general method ofin vitropreparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions

1988 • 2,410 citations

Genetic Approach to Facilitate Purification of Recombinant Proteins with a Novel Metal Chelate Adsorbent

1988 • 1,030 citations

Computer analysis of retroviral pol genes: assignment of enzymatic functions to specific sequences and homologies with nonviral enzymes.

1986 • 483 citations

Correct integration of retroviral DNA in vitro

1987 • 459 citations

The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro

1990 • 411 citations

Activities of human immunodeficiency virus (HIV) integration protein in vitro: specific cleavage and integration of HIV DNA.

1991 • 405 citations

The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro

1990 • 350 citations

Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity.

1990 • 329 citations

The avian retroviral integration protein cleaves the terminal sequences of linear viral DNA at the in vivo sites of integration

1989 • 311 citations

System for High-Level Production in Escherichia coli and Rapid Purification of Recombinant Proteins: Application to Epitope Mapping, Preparation of Antibodies, and Structure—Function Analysis

1990 • 261 citations

The DNA intermediate in yeast Ty1 element transposition copurifies with virus-like particles: Cell-free Ty1 transposition

1988 • 202 citations

Human immunodeficiency virus integration in a cell-free system

1990 • 182 citations

Human immunodeficiency virus integrase protein requires a subterminal position of its viral DNA recognition sequence for efficient cleavage

1991 • 176 citations

Transposition of Mu DNA: Joining of Mu to target DNA can be uncoupled from cleavage at the ends of Mu

1987 • 172 citations

Integration of Retroviral DNA

1990 • 161 citations

DNA binding properties of the integrase proteins of human immunodeficiency viruses types 1 and 2

1991 • 116 citations

A rapid in vitro assay for HIV DNA integration

1991 • 110 citations

Unraveling retrovirus integration

1990 • 102 citations

Intramolecular transposition by Tn10

1989 • 94 citations

The FLP recombinase of the Saccharomyces cerevisiae 2 microns plasmid attaches covalently to DNA via a phosphotyrosyl linkage.

1985 • 94 citations