Integration of Retroviral DNA

Genomic sequencing.

1984 • 8,343 citations

Complete nucleotide sequence of the AIDS virus, HTLV-III

1985 • 2,236 citations

CELLULAR ONCOGENES AND RETROVIRUSES

1983 • 1,671 citations

Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis

1981 • 1,611 citations

DNA TOPOISOMERASES

1985 • 1,524 citations

Structure of Chromatin

1977 • 1,276 citations

SPLICING OF MESSENGER RNA PRECURSORS

1986 • 1,233 citations

Nucleotide sequence of Moloney murine leukaemia virus

1981 • 1,079 citations

NONVIRAL RETROPOSONS: GENES, PSEUDOGENES, AND TRANSPOSABLE ELEMENTS GENERATED BY THE REVERSE FLOW OF GENETIC INFORMATION

1986 • 1,032 citations

Splicing of Messenger RNA Precursors

1984 • 874 citations

Ty elements transpose through an RNA intermediate

1985 • 837 citations

RNA tumor viruses

1982 • 833 citations

Mobile genetic elements

1997 • 630 citations

Form and Function of Retroviral Proviruses

1982 • 627 citations

Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas

1982 • 624 citations

Mobile Genetic Elements

1984 • 574 citations

Protein Import into the Cell Nucleus

1986 • 544 citations

Molecular model for the transposition and replication of bacteriophage Mu and other transposable elements.

1979 • 503 citations

Integration host factor: A protein for all reasons

1988 • 501 citations

Chromatin Structure: Deduced from a Minichromosome

1975 • 462 citations

Correct integration of retroviral DNA in vitro

1987 • 459 citations

A model for initiation at origins of DNA replication

1988 • 452 citations

Retroviral DNA integration: Structure of an integration intermediate

1988 • 397 citations

Retroviral integration: structure of the initial covalent product and its precursor, and a role for the viral IN protein.

1989 • 392 citations

Dilute (d) coat colour mutation of DBA/2J mice is associated with the site of integration of an ecotropic MuLV genome

1981 • 391 citations

A nucleoprotein complex mediates the integration of retroviral DNA.

1989 • 381 citations

Proviruses of avian sarcoma virus are terminally redundant, co-extensive with unintegrated linear DNA and integrated at many sites

1978 • 342 citations

Standardized and simplified nomenclature for proteins common to all retroviruses

1988 • 336 citations

Nucleotide sequences of integrated Moloney sarcoma provirus long terminal repeats and their host and viral junctions.

1980 • 323 citations

Nucleotide sequence of a yeast Ty element: evidence for an unusual mechanism of gene expression.

1985 • 321 citations

Multiple DNA-pRotein Interactions Governing High-Precision DNA Transactions

1986 • 302 citations

Sequence of retrovirus provirus resembles that of bacterial transposable elements

1980 • 288 citations

Structure of a cloned circular Moloney murine leukemia virus DNA molecule containing an inverted segment: implications for retrovirus integration.

1980 • 280 citations

Protein migration into nuclei. I. Frog oocyte nuclei in vivo accumulate microinjected histones, allow entry to small proteins, and exclude large proteins.

1975 • 262 citations

Highly preferred targets for retrovirus integration

1988 • 262 citations

Nucleotide sequences at host–proviral junctions for mouse mammary tumour virus

1981 • 261 citations

Germline integration of Moloney murine leukemia virus at the Mov13 locus leads to recessive lethal mutation and early embryonic death

1983 • 253 citations

Retroviruses as mutagens: Insertion and excision of a nontransforming provirus alter expression of a resident transforming provirus

1981 • 253 citations

Construction and analysis of deletion mutations in the pol gene of moloney murine leukemia virus: A new viral function required for productive infection

1984 • 244 citations

Transpososomes: Stable protein-DNA complexes involved in the in vitro transposition of bacteriophage Mu DNA

1987 • 231 citations

Structure and nucleotide sequence of the putative mammary oncogene int-1; proviral insertions leave the protein-encoding domain intact

1984 • 222 citations

Role of endogenous retroviruses as mutagens: The hairless mutation of mice

1988 • 221 citations

Cellular functions are required for the synthesis and integration of avian sarcoma virus-specific DNA

1977 • 220 citations

6 Protein Biosynthesis and Assembly

1982 • 217 citations

Transposable Elements in Yeast

1983 • 217 citations

Sequence and spacing requirements of a retrovirus integration site

1988 • 215 citations

Acceptor sites for retroviral integrations map near DNase I-hypersensitive sites in chromatin

1986 • 212 citations

The DNA intermediate in yeast Ty1 element transposition copurifies with virus-like particles: Cell-free Ty1 transposition

1988 • 202 citations

The terminal nucleotides of retrovirus DNA are required for integration but not virus production

1983 • 193 citations

An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene

1988 • 187 citations

A mutant murine leukemia virus with a single missense codon in pol is defective in a function affecting integration.

1984 • 182 citations

A 32,000-Dalton nucleic acid-binding protein from avian retravirus cores possesses DNA endonuclease activity

1978 • 182 citations

Transposition of Mu DNA: Joining of Mu to target DNA can be uncoupled from cleavage at the ends of Mu

1987 • 172 citations

Transposon-mediated site-specific recombination in vitro: DNA cleavage and protein-DNA linkage at the recombination site

1981 • 172 citations

Higher Order Structure of Simian Virus 40 Chromatin

1978 • 169 citations

The retrovirus pol gene encodes a product required for DNA integration: identification of a retrovirus int locus.

1984 • 164 citations

8 Pathogenesis of Retrovirus-induced Disease

1982 • 161 citations

Mechanism of transposition of bacteriophage Mu: structure of a transposition intermediate

1985 • 155 citations

Long terminal repeat of murine retroviral DNAs: sequence analysis, host-proviral junctions, and preintegration site

1982 • 154 citations

Role of DNA topology in Mu transposition: Mechanism of sensing the relative orientation of two DNA segments

1986 • 147 citations

Circles with two tandem LTRs are precursors to integrated retrovirus DNA

1984 • 138 citations

Mutants and pseudorevertants of moloney murine leukemia virus with alterations at the integration site

1985 • 135 citations

Insertion Mutagenesis of Embryonal Carcinoma Cells by Retroviruses

1985 • 132 citations

The Fv-1 Gene of the Mouse and its Control of Murine Leukemia Virus Replication

1979 • 132 citations

Nucleotide sequence of cloned unintegrated avian sarcoma virus DNA: viral DNA contains direct and inverted repeats similar to those in transposable elements.

1981 • 130 citations

Physical mapping of the Fv-1 tropism host range determinant of BALB/c murine leukemia viruses

1983 • 129 citations

Effect of Fv-1 gene product on synthesis of linear and supercoiled viral DNA in cells infected with murine leukemia virus

1980 • 124 citations

Intramolecular integration within Moloney murine leukemia virus DNA

1981 • 122 citations

Expression of genes introduced into cells by retroviral infection is more efficient than that of genes introduced into cells by DNA transfection

1984 • 121 citations

Kinetics of synthesis, structure and purification of avian sarcoma virus-specific DNA made in the cytoplasm of acutely infected cells

1978 • 121 citations

The DNA Enzymology of Protein Machines

1984 • 115 citations

Integration of mini-retroviral DNA: a cell-free reaction for biochemical analysis of retroviral integration.

1989 • 111 citations

Endonuclease activity of purified RNA-directed DNA polymerase from avian myeloblastosis virus.

1979 • 100 citations

MECHANISM OF BACTERIOPHAGE MU TRANSPOSITION

1986 • 97 citations

Synthesis and circularization of N- and B-tropic retroviral DNA Fv-1 permissive and restrictive mouse cells.

1980 • 95 citations

Mutations in the gag gene of Moloney murine leukemia virus: effects on production of virions and reverse transcriptase

1984 • 89 citations

Infectious viral DNA of murine leukemia virus.

1975 • 76 citations

Selective cleavage in the avian retroviral long terminal repeat sequence by the endonuclease associated with the alpha beta form of avian reverse transcriptase.

1983 • 71 citations

The palindromic LTR-LTR junction of Moloney murine leukemia virus is not an efficient substrate for proviral integration

1989 • 70 citations

A Rous sarcoma virus provirus is flanked by short direct repeats of a cellular DNA sequence present in only one copy prior to integration.

1981 • 70 citations

Multiple sequence elements are required for regulation of human T-cell leukemia virus gene expression.

1987 • 69 citations

Avian sarcoma and leukosis virus pol-endonuclease recognition of the tandem long terminal repeat junction: minimum site required for cleavage is also required for viral growth

1987 • 64 citations

Mutations in gag proteins P12 and P15 of Moloney murine leukemia virus block early stages of infection

1984 • 64 citations

Construction of mutants of Moloney murine leukemia virus by suppressor-linker insertional mutagenesis: positions of viable insertion mutations.

1984 • 61 citations

Slow virus visna: reproduction in vitro of virus from extrachromosomal DNA.

1984 • 61 citations

Nucleotide sequences of gag-pol regions that determine the Fv-1 host range property of BALB/c N-tropic and B-tropic murine leukemia viruses

1983 • 58 citations

Rous sarcoma virus infection of synchronized cells establishes provirus integration during S-phase DNA synthesis prior to cellular division.

1981 • 57 citations

Circles with two tandem long terminal repeats are specifically cleaved by pol gene-associated endonuclease from avian sarcoma and leukosis viruses: nucleotide sequences required for site-specific cleavage

1985 • 54 citations

Gene product of moloney murine leukemia virus required for proviral integration is a DNA-binding protein

1988 • 47 citations

Mechanism of Action of the Endonuclease Associated with the αβ and ββ Forms of Avian RNA Tumor Virus Reverse Transcriptase

1983 • 47 citations

Point mutations in the P30 domain of thegag gene of moloney murine leukemia virus

1985 • 46 citations

Site-specific nicking at the avian retrovirus LTR circle junction by the viral pp32 DNA endonuclease

1985 • 45 citations

Interferon inhibits transformation by murine sarcoma viruses before integration of provirus

1980 • 43 citations

Analysis of mutant Moloney murine leukemia viruses containing linker insertion mutations in the 3' region of pol

1988 • 39 citations

Construction and Recovery of Viable Retroviral Genomes Carrying a Bacterial Suppressor Transfer RNA Gene

1985 • 39 citations

Reversal of Fv-1 host range by in vitro restriction endonuclease fragment exchange between molecular clones of N-tropic and B-tropic murine leukemia virus genomes

1983 • 38 citations

Virus-coded DNA endonuclease from avian retrovirus

1981 • 34 citations

Dynamic, Sequence-dependent DNA Structure as Exemplified by Cruciform Extrusion from Inverted Repeats in Negatively Supercoiled DNA

1983 • 32 citations

Nuclease mechanism of the avian retrovirus pp32 endonuclease

1986 • 30 citations

Retroviral DNA integrated during infection by an integration-deficient mutant of murine leukemia virus is oligomeric

1987 • 30 citations

Molecular cloning and partial characterization of unintegrated linear DNA from gibbon ape leukemia virus.

1981 • 25 citations

Retroviral insertional mutagenesis of a target allele in a heterozygous murine cell line.

1985 • 25 citations

An X-Linked Gene Affecting Mouse Cell DNA Synthesis Also Affects Production of Unintegrated Linear and Supercoiled DNA of Murine Leukemia Virus

1984 • 24 citations

Characterization of endonuclease activities in Moloney murine leukemia virus and its replication-defective mutants

1987 • 23 citations

Integration and expression of several molecular forms of Rous sarcoma virus DNA used for transfection of mouse cells.

1984 • 23 citations

Avian sarcoma-leukosis virus pol-endo proteins expressed independently in mammalian cells accumulate in the nucleus but can be directed to other cellular compartments

1988 • 20 citations

Fate of Unintegrated Viral DNA in Fv-1 Permissive and Resistant Mouse Cells Infected with Murine Leukemia Virus

1981 • 19 citations

The Genetics of Murine Leukemia Viruses

1984 • 19 citations

Isolation of an integrated provirus of Moloney murine leukemia virus with long terminal repeats in inverted orientation: integration utilizing two U3 sequences

1988 • 18 citations

Molecular Basis of Blood Diseases.

1988 • 15 citations

Integration of Rous sarcoma virus DNA during transfection

1981 • 13 citations

An X-linked gene affecting mouse cell DNA synthesis also affects production of unintegrated linear and supercoiled DNA of murine leukemia virus.

1984 • 11 citations

Studies with aphidicolin on the Fv-1 host restriction of Friend murine leukemia virus

1982 • 10 citations

The spleen necrosis virus int gene product expressed in Escherichia coli has DNA binding activity and mediates att and U5-specific DNA multimer formation in Vitro

1987 • 10 citations

Fv-1 host cell restriction of friend leukemia virus: microinjection of unintegrated viral DNA

1984 • 6 citations