Transgenic mouse model of the mild dominant form of osteogenesis imperfecta.

Functional inactivation of genes by dominant negative mutations

1987 • 1,174 citations

Extracellular matrix biochemistry

1984 • 1,038 citations

Volume-conducted potentials in response to auditory stimuli as detected by averaging in the cat

1970 • 592 citations

The influence of age and sex on skin thickness, skin collagen and density

1975 • 582 citations

Structure, Function, and Adaptation of Compact Bone

1989 • 473 citations

Embryonic lethal mutation in mice induced by retrovirus insertion into the α1(I) collagen gene

1983 • 422 citations

Contribution of collagen and mineral to the elastic-plastic properties of bone

1975 • 390 citations

Osteogenesis Imperfecta

1981 • 378 citations

Embryonic lethal mutation in mouse collagen I gene causes rupture of blood vessels and is associated with erythropoietic and mesenchymal cell death

1984 • 285 citations

The mechanical characteristics of cancellous bone at the upper femoral region

1983 • 236 citations

Perinatal lethal osteogenesis imperfecta in transgenic mice bearing an engineered mutant pro-α1(I) collagen gene

1988 • 235 citations

Insertion of retrovirus into the first intron of alpha 1(I) collagen gene to embryonic lethal mutation in mice.

1984 • 229 citations

Altered triple helical structure of type I procollagen in lethal perinatal osteogenesis imperfecta.

1985 • 217 citations

Retrovirus-induced de novo methylation of flanking host sequences correlates with gene inactivity

1985 • 199 citations

Coordinate regulation of the levels of type III and type I collagen mRNA in most but not all mouse fibroblasts.

1985 • 194 citations

Comparison of the trabecular and cortical tissue moduli from human iliac crests

1989 • 163 citations

Type I osteogenesis imperfecta: a nonfunctional allele for pro alpha 1 (I) chains of type I procollagen.

1982 • 137 citations

Retrovirus-induced lethal mutation in collagen I gene of mice is associated with an altered chromatin structure

1984 • 126 citations

Collagen defects in lethal perinatal osteogenesis imperfecta

1986 • 126 citations

Retrovirus insertion inactivates mouse α 1(I) collagen gene by blocking initiation of transcription

1986 • 118 citations

Retrovirus-induced insertional mutation in Mov13 mice affects collagen I expression in a tissue-specific manner

1989 • 111 citations

Frameshift mutation near the 3' end of the COL1A1 gene of type I collagen predicts an elongated Pro alpha 1(I) chain and results in osteogenesis imperfecta type I.

1990 • 91 citations

Osteogenesis Imperfecta after the Menopause

1984 • 89 citations

Normal epithelial branching morphogenesis in the absence of collagen I

1986 • 84 citations

Osteogenesis imperfecta. The position of substitution for glycine by cysteine in the triple helical domain of the pro alpha 1(I) chains of type I collagen determines the clinical phenotype.

1989 • 79 citations

Hearing and Middle Ear Function in Osteogenesis Imperfecta

1982 • 59 citations

Clinical variability of osteogenesis imperfecta reflecting molecular heterogeneity: cysteine substitutions in the alpha 1(I) collagen chain producing lethal and mild forms.

1986 • 52 citations

The molecular defect in an autosomal dominant form of osteogenesis imperfecta. Synthesis of type I procollagen containing cysteine in the triple-helical domain of pro-alpha 1(I) chains.

1986 • 51 citations

Substitution of cysteine for glycine within the carboxyl-terminal telopeptide of the alpha 1 chain of type I collagen produces mild osteogenesis imperfecta.

1988 • 39 citations

An abnormal collagen alpha chain containing cysteine in autosomal dominant osteogenesis imperfecta.

1984 • 36 citations

Collagen synthesis by cell lines derived from Mov-13 mouse embryos which have a lethal mutation in the collagen α 1(I) gene

1987 • 15 citations

The effect of sex and site on the composition of skin in the rat and mouse

1964 • 13 citations

Osteogenesis imperfecta after the menopause

1983 • 5 citations