Glucocorticoids inhibit the induction of nitric oxide synthase and the related cell damage in adenocarcinoma cells

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

Nitric oxide: A cytotoxic activated macrophage effector molecule

1988 • 2,050 citations

Macrophage Cytotoxicity: Role for L-Arginine Deiminase and Imino Nitrogen Oxidation to Nitrite

1987 • 1,533 citations

Biosynthesis of nitric oxide from l-arginine

1989 • 1,220 citations

Goodman and Gilman's The Pharmacological Basis of Therapeutics.

1986 • 1,091 citations

L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells.

1987 • 958 citations

Comparative pharmacology of endothelium‐derived relaxing factor, nitric oxide and prostacyclin in platelets

1987 • 824 citations

Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine.

1990 • 751 citations

Induction of nitrite/nitrate synthesis in murine macrophages by BCG infection, lymphokines, or interferon-gamma.

1987 • 722 citations

Dexamethasone prevents the induction by endotoxin of a nitric oxide synthase and the associated effects on vascular tone: An insight into endotoxin shock

1990 • 596 citations

Rapid colormetric assay for cell viability: Application to the quantitation of cytotoxic and growth inhibitory lymphokines

1984 • 561 citations

[24] Nitrate reductase from higher plants

1980 • 507 citations

Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxide.

1989 • 464 citations

Glucocorticoids inhibit the induction of nitric oxide synthase in macrophages

1990 • 455 citations

Hepatocytes produce nitrogen oxides from L-arginine in response to inflammatory products of Kupffer cells.

1989 • 405 citations

Anti-inflammatory glucocorticoids inhibit the induction by endotoxin of nitric oxide synthase in the lung, liver and aorta of the rat

1990 • 389 citations

An L-arginine-dependent mechanism mediates kupffer cell inhibition of hepatocyte protein synthesis in vitro

1989 • 325 citations

Therapeutic concentrations of glucocorticoids suppress the antimicrobial activity of human macrophages without impairing their responsiveness to gamma interferon.

1985 • 206 citations

Antiinflammatory steroid action: Basic and clinical aspects

1990 • 202 citations

SHORT COMMUNICATION: Cytokines Induce an L-Arginine-Dependent Effector System in Nonmacrophage Cells

1988 • 133 citations

Inhibition of O2- generation by dexamethasone is mimicked by lipocortin I in alveolar macrophages.

1989 • 108 citations

Glucocorticoid-Induced Impairment of Macrophage Antimicrobial Activity: Mechanisms and Dependence on the State of Activation

1987 • 75 citations

Antiproliferative activity of gamma-interferon combined with lipopolysaccharide on murine adenocarcinoma: dependence on an L-arginine metabolism with production of nitrite and citrulline.

1989 • 64 citations

Inhibition of macrophage tumoricidal activity by glucocorticoids.

1988 • 52 citations

Catalytic acceleration of the urea-diacetylmonoxime-phenazone reaction and its application to automatic analysis

1965 • 43 citations

Effect of hydrocortisone on macrophage response to lymphokine

1982 • 43 citations

Effects of various inhibitors of arachidonic acid oxygenation on macrophage superoxide release and tumoricidal activity.

1985 • 35 citations

N G -モノ,ジ-およびトリメチル化アルギニンの調製と性質

1977 • 22 citations

Rat macrophage treatment with lipopolysaccharide leads to a reduction in respiratory burst product secretion and a decrease in NADPH oxidase affinity

1987 • 12 citations