T-cell hybridomas which produce B lymphocyte replication factors only

Identification of a T cell-derived b cell growth factor distinct from interleukin 2.

1982 • 1,095 citations

FUNCTION OF MACROPHAGES IN ANTIGEN RECOGNITION BY GUINEA PIG T LYMPHOCYTES

1973 • 1,046 citations

A plaque assay for all cells secreting Ig of a given type or class

1976 • 1,034 citations

Separation of cells by velocity sedimentation

1969 • 988 citations

Replacement of T-Cell Function by a T-Cell Product

1972 • 537 citations

Complete replacement of serum by albumin, transferrin, and soybean lipid in cultures of lipopolysaccharide-reactive B lymphocytes.

1978 • 535 citations

Induction of immunoglobulin and antibody synthesis in vitro by lipopolysaccharides

1972 • 431 citations

Is There Evidence for a Non-Antigen Specific Diffusable Chemical Mediator from the Thymus-Derived Cell in the Initiation of the Immune Response?**Supported by U. S. Public Health Service Research Grant AI-08795-03 and American Cancer Society Research Grant E-395-D.

1971 • 276 citations

Cell Interactions Between Histoincompatible T and B Lymphocytes. The H-2 Gene Complex Determines Successful Physiologic Lymphocyte Interactions

1973 • 241 citations

ACTIVATION OF T AND B LYMPHOCYTES IN VITRO

1974 • 231 citations

T-cell-dependent B-cell stimulation is H-2 restricted and antigen dependent only at the resting B-cell level.

1980 • 191 citations

Induction and Suppression of Polyclonal Antibody Responses by Anti‐Ig Reagents and Antigen‐Nonspecific Helper Factors:

1980 • 169 citations

T cell factor which can replace T cells in vivo

1974 • 156 citations

Role of H‐2 Gene Products in the Function of T Helper Cells from Normal and Chimeric Mice in Vivo¹

1978 • 153 citations

Thrombin and epidermal growth factor become linked to cell surface receptors during mitogenic stimulation

1979 • 140 citations

Specific Collaboration between T and B Lymphocytes across a Cell Impermeable Membrane in vitro

1972 • 132 citations

Identification of the octapeptide [Met]enkephalin -Arg6-Gly7-Leu8 in extracts of bovine adrenal medulla

1981 • 118 citations

T cell-dependent activation of resting B cells: requirement for both nonspecific unrestricted and antigen-specific Ia-restricted soluble factors.

1981 • 115 citations

Direct linkage of epidermal growth factor to its receptor

1979 • 113 citations

H‐2‐unrestricted polyclonal maturation without replication of small B cells induced by antigen‐activated T cell help factors

1980 • 112 citations

Clonal Induction of Helper T Cells: Conversion of Specific Signals into Nonspecific Signals

1980 • 97 citations

Antigen-specific T-helper cells stimulate H-2-compatible and H-2-incompatible B-cell blasts polyclonally.

1980 • 94 citations

A large product of cell-free translation of messenger RNA coding for corticotropin.

1976 • 84 citations

The protein-coding sequence of the bovine ACTH-β-LPH precursor gene is split near the signal peptide region

1980 • 82 citations

Haematopoietic growth factors are released in cultures of H–2-restricted helper T cells, accessory cells and specific antigen

1980 • 64 citations

Derivation of hybrids between a thymoma line and spleen cells activated in a mixed leukocyte reaction

1977 • 59 citations

Roles of Surface‐Bound Immunoglobulin Molecules in Regulating the Replication and Maturation to Immunoglobulin Secretion of B Lymphocytes

1980 • 54 citations

Mitogen-activated B-cell blasts reactive to more than one mitogen.

1979 • 53 citations

In vitro analysis of allogeneic lymphocyte interaction. I. Characterization and cellular origin of an Ia-positive helper factor- allogeneic effect factor

1977 • 45 citations

Properties of educated T cells. The ability of educated T cells to facilitate the immune response to non‐cross‐reacting antigens in vitro

1973 • 23 citations

An Approach to the Modeling of Mixing of Elastomers

1981 • 21 citations