Reduced bikunin gene expression as a factor of poor prognosis in ovarian carcinoma

EGFR and cancer prognosis

2001 • 2,068 citations

The urokinase-type plasminogen activator system in cancer metastasis: A review

1997 • 1,561 citations

Ovarian cancer: Epidemiology, biology, and prognostic factors

2000 • 702 citations

Plasminogen Activators and Matrix Metalloproteinases in Angiogenesis

1996 • 341 citations

Clinical Relevance of Invasion Factors Urokinase-Type Plasminogen Activator and Plasminogen Activator Inhibitor Type 1 for Individualized Therapy Decisions in Primary Breast Cancer Is Greatest When Used in Combination

2002 • 122 citations

Plasmin/Plasminogen System in Colorectal Cancer

2002 • 121 citations

Impact of urokinase-type plasminogen activator and its inhibitor type 1 on prognosis in cervical cancer of the uterus.

1994 • 107 citations

Cyclooxygenase-2 (COX-2), Epidermal Growth Factor Receptor (EGFR), and Her-2/neu Expression in Ovarian Cancer

2002 • 98 citations

Inhibitory Effect of a Conjugate between Human Urokinase and Urinary Trypsin Inhibitor on Tumor Cell Invasion in Vitro

1995 • 97 citations

The Role of the HER-2/neu Oncogene in Gynecologic Cancers

1996 • 76 citations

6 The urokinase/urokinase-receptor system and cancer invasion

1995 • 74 citations

Inhibition of the soluble and the tumor cell receptor-bound plasmin by urinary trypsin inhibitor and subsequent effects on tumor cell invasion and metastasis.

1994 • 73 citations

E-cadherin and urokinase-type plasminogen activator tissue status in gastric carcinoma

1995 • 73 citations

Suppression of Urokinase Expression and Invasiveness by Urinary Trypsin Inhibitor Is Mediated through Inhibition of Protein Kinase C- and MEK/ERK/c-Jun-dependent Signaling Pathways

2001 • 72 citations

Clinical relevance of the urokinase plasminogen activator system in breast cancer

1999 • 64 citations

A bifunctional hybrid molecule of the amino‐terminal fragment of urokinase and domain II of bikunin efficiently inhibits tumor cell invasion and metastasis

1998 • 62 citations

Characterization of the cellular binding site for the urinary trypsin inhibitor.

1994 • 57 citations

Anti-metastatic therapy by urinary trypsin inhibitor in combination with an anti-cancer agent

1995 • 47 citations

Inhibition of metastasis of lewis lung carcinoma by urinary trypsin inhibitor in experimental and spontaneous metastasis models

1995 • 45 citations

Inhibition of tumor cell invasion through matrigel by a peptide derived from the domain II region in urinary trypsin inhibition.

1995 • 42 citations

Effects of urinary trypsin inhibitor on the invasion of reconstituted basement membranes by ovarian cancer cells

1994 • 40 citations

The role of the HER-2/ oncogene in gynecologic cancers

1996 • 38 citations

Urinary trypsin inhibitor (UTI) and fragments derived from UTI by limited proteolysis efficiently inhibit tumor cell invasion

1994 • 37 citations

Prognostic impact of stromal cell-derived urokinase-type plasminogen activator in gastric carcinoma

1999 • 36 citations

Structure and function analysis of urinary trypsin inhibitor (UTI): identification of binding domains and signaling property of UTI by analysis of truncated proteins

2001 • 31 citations

Immunohistochemical Distribution of Inter-α-trypsin Inhibitor Chains in Normal and Malignant Human Lung Tissue

1999 • 31 citations

Gene Expression of the Two Heavy Chains and One Light Chain Forming the Inter-Alpha-Trypsin-Inhibitor in Human Tissues.

1998 • 30 citations

Characterization of Binding Properties of Urinary Trypsin Inhibitor to Cell-associated Binding Sites on Human Chondrosarcoma Cell Line HCS-2/8

2001 • 29 citations

Identification and characterization of the cell-associated binding protein for urinary trypsin inhibitor

1998 • 28 citations

Expression of Ets-1 Is Correlated with Urokinase-Type Plasminogen Activator and Poor Prognosis in Pulmonary Adenocarcinoma

2001 • 28 citations

Urinary trypsin inhibitor efficiently inhibits urokinase production in tumor necrosis factor-stimulated cells.

1996 • 27 citations

Suppression of urokinase-type plasminogen activator expression from human ovarian cancer cells by urinary trypsin inhibitor

2000 • 23 citations

Can Axillary Dissection be Avoided by Improved Molecular Biological Diagnosis?

2000 • 18 citations

Human myometrial cells in culture express specific binding sites for urinary trypsin inhibitor

2000 • 15 citations

Urinary trypsin inhibitor, a Kunitz-type protease inhibitor, modulates tumor necrosis factor-stimulated activation and translocation of protein kinase C in U937 cells.

1998 • 10 citations

Production of a hybrid protein consisting of the N-terminal fragment of urokinase and the C-terminal domain of urinary trypsin inhibitor in Escherichia coli.

1998 • 9 citations