Future directions in hyperthermia biology

Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy.

1991 • 1,591 citations

Design of Liposomes for Enhanced Local Release of Drugs by Hyperthermia

1978 • 896 citations

Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: implications for therapy.

1990 • 742 citations

Hyperthermia and Cancer

1982 • 474 citations

Hyperthermia and Cancer

1983 • 426 citations

Increased microvascular permeability contributes to preferential accumulation of Stealth liposomes in tumor tissue.

1993 • 368 citations

Tumour microcirculation as a target for hyperthermia

1986 • 294 citations

Sensitivity of hyperthermia trial outcomes to temperature and time: Implications for thermal goals of treatment

1993 • 282 citations

Antibody-targeted delivery of doxorubicin entrapped in sterically stabilized liposomes can eradicate lung cancer in mice.

1993 • 239 citations

Inhibitors of nitric oxide synthase selectively reduce flow in tumour‐associated neovasculature

1992 • 179 citations

Pharmacokinetics and antitumor activity of epirubicin encapsulated in long‐circulating liposomes incorporating a polyethylene glycol‐derivatized phospholipid

1992 • 145 citations

Interstitial fluid pressure in solid tumors following hyperthermia: possible correlation with therapeutic response.

1992 • 132 citations

International Journal of Hyperthermia

2002 • 125 citations

Determinants of capillary permeability: a review of mechanisms based on single capillary studies in the frog.

1986 • 95 citations

Human tumor extracellular pH as a function of blood glucose concentration

1994 • 90 citations

Adaptation to low pH modifies thermal and thermo-chemical responses of mammalian cells

1986 • 87 citations

MR imaging and spectroscopy for prognostic evaluation in soft-tissue sarcomas.

1994 • 73 citations

Effect of hypoxia and acidosis on the cytotoxicity of four platinum complexes at normal and hyperthermic temperatures.

1988 • 66 citations

Increase in thermosensitivity of tumor cells by lowering intracellular pH.

1993 • 59 citations

Treatment of Murine SCC VII Tumors with Localized Hyperthermia and Temperature-Sensitive Liposomes Containing Cisplatin

1990 • 57 citations

Equivalence of continuous and pulse simulated low dose rate irradiation in 9L gliosarcoma cells at 37° and 41°C

1992 • 54 citations

What is Nitric Oxide and Why Are So Many People Studying It?

1993 • 45 citations

Enhancement of hyperthermia effect in vivo by amiloride and dids

1993 • 42 citations

The use of hydralazine to manipulate tumour temperatures during hyperthermia

1990 • 38 citations

Effect of hypertherrnia on cisplatin pharrnacokinetics in normal dogs

1986 • 36 citations

Use of nitroprusside to increase tissue temperature during local hyperthermia in normal and tumor-bearing dogs

1992 • 35 citations

Hyperthermic sensitization by the radical initiator 2,2′-azobis (2-amidinopropane) dihydrochloride (AAPH). I.In vitrostudies

1994 • 34 citations

THE USE OF HYPERTHERMIA WITHIN THE FRAME OF CANCER MULTISTEP THERAPY

1980 • 29 citations

The relationship between the unmodified initial tissue pH of human tumours and the response to combined radiotherapy and local hyperthermia treatment

1989 • 27 citations

Manipulation of intra- and extracellular pH in spontaneous canine tumours by use of hyperglycaemia

1993 • 21 citations

Effects of acute pH 6.6 and 42.0 degrees C heating on the intracellular pH of Chinese hamster ovary cells.

1988 • 21 citations

Hyperthermia-Induced Enhancement of Melphalan Activity against a Melphalan-Resistant Human Rhabdomyosarcoma Xenograft

1992 • 16 citations

Mechanisms of heat removal during local hyperthermia

1989 • 16 citations

Hyperthermic modulation of radiolabeled antibody (mab) uptake in tumors and normal tissues

1992 • 4 citations