Inositol cyclic triphosphate [inositol 1,2-(cyclic)-4,5-triphosphate] is formed upon thrombin stimulation of human platelets.
Data up to Jan 2025
Total Citations Per Year
Abstract
References (21)
Calcium's Role in Mechanotransduction during Muscle Development
2014 • 14,293 citations
The role of protein kinase C in cell surface signal transduction and tumour promotion
1984 • 7,521 citations
Inositol trisphosphate, a novel second messenger in cellular signal transduction
1984 • 6,088 citations
Inositol trisphosphate and diacylglycerol as second messengers
1984 • 3,535 citations
The inositol tris/tetrakisphosphate pathway—demonstration of Ins(l,4,5)P3 3-kinase activity in animal tissues
1986 • 702 citations
Rapid formation of inositol 1,3,4,5-tetrakisphosphate following muscarinic receptor stimulation of rat cerebral cortical slices
1985 • 641 citations
Mass changes in myoinositol trisphosphate in human platelets stimulated by thrombin. Inhibitory effects of phorbol ester.
1985 • 292 citations
Isolation of a phosphomonoesterase from human platelets that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate.
1985 • 233 citations
Hydrolysis of polyphosphoinositides by purified sheep seminal vesicle phospholipase C enzymes.
1984 • 225 citations
[12] Isolation of human platelets and platelet surface membranes
1974 • 213 citations
Phosphoinositide interconversion in thrombin-stimulated human platelets.
1985 • 205 citations
The enzymic formation of myoinositol 1:2-cyclic phosphate from phosphatidylinositol
1971 • 177 citations
Isolation and characterization of the inositol cyclic phosphate products of polyphosphoinositide cleavage by phospholipase C. Physiological effects in permeabilized platelets and Limulus photoreceptor cells.
1985 • 167 citations
Production of phosphoinositide-derived messengers
1984 • 163 citations
Isolation and characterization of the inositol cyclic phosphate products of phosphoinositide cleavage by phospholipase C. Metabolism in cell-free extracts.
1986 • 105 citations
Inositol cyclic phosphates are produced by cleavage of phosphatidylphosphoinositols (polyphosphoinositides) with purified sheep seminal vesicle phospholipase C enzymes.
1985 • 103 citations
The formation of inositol 1,2-cyclic phosphate on agonist stimulation of phosphoinositide breakdown in mouse pancreatic minilobules. Evidence for direct phosphodiesteratic cleavage of phosphatidylinositol.
1985 • 60 citations
Phosphatidylinositol 4,5-bisphosphate may represent the site of release of plasma membrane-bound calcium upon stimulation of human platelets
1984 • 59 citations
Separation of inositol phosphates and glycerophosphoinositol phosphates by high-performance liquid chromatography
1985 • 56 citations
Isolation of cyclic inositol-1,2-phosphate from mammalian cells and a probable function of phosphatidylinositol turnover
1974 • 32 citations
18O labeling of adenine nucleotide alpha-phosphoryls in platelets. Contribution by phosphodiesterase-catalyzed hydrolysis of cAMP.
1983 • 32 citations
Cited By (0)
No citing papers found in database