The use of the Calvert formula to determine the optimal carboplatin dosage

Prediction of Creatinine Clearance from Serum Creatinine

1976 • 15,066 citations

Carboplatin dosage: prospective evaluation of a simple formula based on renal function.

1989 • 1,831 citations

Glomerular filtration rate measurement in man by the single injection methods using 51Cr-EDTA.

1969 • 443 citations

Relationships between carboplatin exposure and tumor response and toxicity in patients with ovarian cancer.

1992 • 369 citations

Pharmacokinetics and dosage reduction of cis-diammine(1,1-cyclobutanedicarboxylato)platinum in patients with impaired renal function.

1984 • 304 citations

Improved therapeutic index of carboplatin plus cyclophosphamide versus cisplatin plus cyclophosphamide: final report by the Southwest Oncology Group of a phase III randomized trial in stages III and IV ovarian cancer.

1992 • 292 citations

Chemotherapy in advanced ovarian cancer: an overview of randomised clinical trials. Advanced Ovarian Cancer Trialists Group.

1991 • 291 citations

Chemotherapy in advanced ovarian cancer: An overview of randomised clinical trials

1991 • 272 citations

Clinical Pharmacokinetics of Carboplatin

1991 • 247 citations

Carboplatin

1989 • 194 citations

Carboplatin pharmacokinetics in children: the development of a pediatric dosing formula. The United Kingdom Children's Cancer Study Group.

1993 • 141 citations

Validity of creatinine clearance estimates in the assessment of renal function

1990 • 114 citations

Effects of cisplatin on different measures of glomerular function in the human kidney with special emphasis on high-dose

1988 • 111 citations

Effectiveness of carboplatin, etoposide, and bleomycin combination chemotherapy in good-prognosis metastatic testicular nonseminomatous germ cell tumors.

1991 • 103 citations

Phase I study of escalating targeted doses of carboplatin combined with ifosfamide and etoposide in children with relapsed solid tumors.

1993 • 85 citations

Platinum complexes in cancer medicine: pharmacokinetics and pharmacodynamics in relation to toxicity and therapeutic activity.

1993 • 80 citations

Carboplatin in the treatment of advanced breast cancer: a phase II study using a pharmacokinetically guided dose schedule.

1993 • 78 citations

Carboplatin versus cisplatin

1993 • 68 citations

The disposition of carboplatin in ovarian cancer patients

1988 • 48 citations

Dose-toxicity relationship of carboplatin in combination with cyclophosphamide in ovarian cancer patients

1991 • 45 citations

Carboplatin and etoposide pharmacokinetics in patients with testicular teratoma

1989 • 43 citations

The optimisation of carboplatin dose in carboplatin, etoposide and bleomycin combination chemotherapy for good prognosis metastatic nonseminomatous germ cell tumours of the testis

1992 • 41 citations

A novel pharmacodynamically based approach to dose optimization of carboplatin when used in combination with etoposide.

1989 • 36 citations

Impact of cyclophosphamide on relationships between carboplatin exposure and response or toxicity when used in the treatment of advanced ovarian cancer.

1993 • 36 citations

Treatment of advanced ovarian cancer: 10 years of experience

1992 • 28 citations

Renal handling of carboplatin

1992 • 24 citations

Advanced ovarian cancer. Carboplatin versus cisplatin.

1993 • 22 citations

Calculation of ⁵¹Cr‐EDTA clearance in children from the activity in one plasma sample by transformation of the biexponential plasma time‐activity curve into a monoexponential with identical integral area below the time‐activity curve

1984 • 21 citations

Phase I study of the combination of monthly carboplatin and weekly cisplatin

1991 • 20 citations

Ifosfamide, carboplatin, and etoposide plus granulocyte-macrophage colony-stimulating factor: a phase I study with apparent activity in non-small-cell lung cancer.

1994 • 20 citations

Single agent activity of carboplatin in patients with previously untreated non-seminomatous germ cell tumours

1992 • 20 citations

Carboplatin dose in combination chemotherapy for testicular cancer

1991 • 19 citations

Pneumothorax after fine needle aspiration of the breast

1991 • 13 citations

Intraperitoneal-administered carboplatin in patients with ovarian cancer; influence of a dwell-time on toxicity and response

1994 • 12 citations

Dose intensity of carboplatin in combination with cyclophosphamide or ifosfamide

1990 • 10 citations

Is creatinine clearance a sufficient measurement for GFR in carboplatin dose calculation?

1993 • 7 citations

Carboplatin dose optimization (I: Reply)

1990 • 3 citations