Evidence for the involvement of DNA-dependent protein kinase in the phenomena of low dose hyper-radiosensitivity and increased radioresistance

The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen

1993 • 1,219 citations

The DNA-dependent protein kinase

1999 • 896 citations

Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

1994 • 637 citations

DNA-Dependent Kinase (p350) as a Candidate Gene for the Murine SCID Defect

1995 • 610 citations

Low-dose hypersensitivity: current status and possible mechanisms

2001 • 554 citations

Absence of p350 Subunit of DNA-Activated Protein Kinase from a Radiosensitive Human Cell Line

1995 • 530 citations

The Response of Chinese Hamster V79 Cells to Low Radiation Doses: Evidence of Enhanced Sensitivity of the Whole Cell Population

1993 • 293 citations

Identification of Genes Involved in Repair of DNA Double-Strand Breaks in Mammalian Cells

1998 • 286 citations

DNA double-strand break repair

1999 • 209 citations

Induction of Stress Genes by Low Doses of Gamma Rays

1999 • 185 citations

DNA-PK: at the cross-roads of biochemistry and genetics

1997 • 169 citations

Identification and characterization of X-ray-induced proteins in human cells.

1989 • 166 citations

Isolation of Two Cell Lines from a Human Malignant Glioma Specimen Differing in Sensitivity to Radiation and Chemotherapeutic Drugs

1993 • 165 citations

Renal Damage in the Mouse: The Response to Very Small Doses per Fraction

1988 • 164 citations

Ku86 Defines the Genetic Defect and Restores X-Ray Resistance and V(D)J Recombination to Complementation Group 5 Hamster Cell Mutants

1996 • 156 citations

Low dose hyper-radiosensitivity and increased radioresistance in mammalian cells

1997 • 143 citations

Hypersensitivity of a Human Tumour Cell Line to Very Low Radiation Doses

1993 • 135 citations

Low-dose hypersensitivity after fractionated low-dose irradiation in vitro

2001 • 124 citations

Low-Dose Hypersensitivity and Increased Radioresistance in a Panel of Human Tumor Cell Lines with Different Radiosensitivity

1996 • 120 citations

Effects of cell cycle phase on low-dose hyper-radiosensitivity

2003 • 98 citations

Low dose hypersensitivity in the T98G human glioblastoma cell line

1999 • 96 citations

Induction of Transcription of "Immediate Early Genes" by Low-Dose Ionizing Radiation

1995 • 95 citations

The Elimination of Low-Dose Hypersensitivity in Chinese Hamster V79-379A Cells by Pretreatment with X Rays or Hydrogen Peroxide

1995 • 92 citations

Low-Dose Hypersensitivity in Chinese Hamster V79 Cells Targeted with Counted Protons Using a Charged-Particle Microbeam

2001 • 85 citations

Use of a cell sorter for assays of cell clonogenicity.

1986 • 81 citations

Automated counting of mammalian cell colonies

2000 • 77 citations

Frameshift Mutation inPRKDC, the Gene for DNA-PKcs, in the DNA Repair-Defective, Human, Glioma-Derived Cell Line M059J

2001 • 69 citations

Underprediction of human skin erythema at low doses per fraction by the linear quadratic model

1996 • 65 citations

Complementation of the Radiosensitive M059J Cell Line

2000 • 64 citations

Low-Dose Radiation Sensitivity and Induced Radioresistance to Cell Killing in HT-29 Cells Is Distinct from the "Adaptive Response" and Cannot Be Explained by a Subpopulation of Sensitive Cells

1997 • 63 citations

Decreased DNA-PK activity in human cancer cells exhibiting hypersensitivity to low-dose irradiation

2000 • 60 citations

Small Doses of High-Linear Energy Transfer Radiation Increase the Radioresistance of Chinese Hamster V79 Cells to Subsequent X Irradiation

1996 • 54 citations

Radioresponsiveness at low doses: hyper-radiosensitivity and increased radioresistance in mammalian cells

1999 • 53 citations

Complementation of the radiosensitive phenotype in severe combined immunodeficient mice by human chromosome 8.

1993 • 47 citations

Modification of survival by DNA repair modifiers: a probable explanation for the phenomenon of increased radioresistance

2000 • 46 citations

Response of V79 cells to low doses of X-rays and negative-mesons: clonogenic survival and DNA strand breaks

1996 • 32 citations

Effects of Low-Dose Neutrons Applied at Reduced Dose Rate on Human Melanoma Cells

2000 • 30 citations

Micronucleus frequencies in cytokinesis-blocked human B lymphocytes after low dose gamma-irradiation

1998 • 28 citations

Low-dose hypersensitivity of V79 cells under exposure to γ-rays and 4 He ions of different energies: survival and chromosome aberrations

2001 • 28 citations

Low Doses of Neutrons Induce Changes in Gene Expression

1994 • 24 citations

Mechanisms and implications of the low dose intrinsic radiation survival response

1996 • 3 citations