Receptor kinase‐dependent desensitization of the muscarinic K+ current in rat atrial cells.

Low access resistance perforated patch recordings using amphotericin B

1991 • 935 citations

Role of βγ Subunits of G Proteins in Targeting the β-Adrenergic Receptor Kinase to Membrane-Bound Receptors

1992 • 703 citations

Activation of the cloned muscarinic potassium channel by G protein βγ subunits

1994 • 472 citations

Acetylcholine activation of single muscarinic K+ channels in isolated pacemaker cells of the mammalian heart

1983 • 471 citations

β-Adrenergic Receptor Kinase: Primary Structure Delineates a Multigene Family

1989 • 451 citations

The effect of GTP and Mg2+ on the GTPase activity and the fluorescent properties of Go.

1987 • 231 citations

Sequestration of muscarinic acetylcholine receptor m2 subtypes. Facilitation by G protein-coupled receptor kinase (GRK2) and attenuation by a dominant-negative mutant of GRK2.

1994 • 150 citations

The relationship between contraction and intracellular sodium in rat and guinea‐pig ventricular myocytes.

1992 • 109 citations

G Protein‐Coupled Receptor Kinases

1994 • 104 citations

Short-term desensitization of muscarinic K+ channel current in isolated atrial myocytes and possible role of GTP-binding proteins

1987 • 100 citations

Correlation of agonist-induced phosphorylation of chick heart muscarinic receptors with receptor desensitization.

1987 • 98 citations

Regulation of spontaneous opening of muscarinic K+ channels in rabbit atrium.

1991 • 85 citations

Activation by G protein beta gamma subunits of beta-adrenergic and muscarinic receptor kinase.

1993 • 83 citations

The negative inotropic effect of acetylcholine on ferret ventricular myocardium.

1988 • 74 citations

The target sets the tempo

1992 • 72 citations

Modulation of acetylcholine‐activated K+ channel function in rat atrial cells by phosphorylation.

1991 • 68 citations

On the role of G protein activation and phosphorylation in desensitization to acetylcholine in guinea‐pig atrial cells.

1993 • 53 citations

Activation of a GTP‐Binding Protein and a GTP‐Binding‐Protein‐Coupled Receptor Kinase (β‐Adrenergic‐Receptor Kinase‐1) by a Muscarinic Receptor m2 Mutant Lacking Phosphorylation Sites

1994 • 41 citations

Desensitization to acetylcholine in single sinoatrial node cells isolated from rabbit hearts

1992 • 32 citations