Fast Kinetics of Exocytosis Revealed by Simultaneous Measurements of Presynaptic Capacitance and Postsynaptic Currents at a Central Synapse

Glutamate receptor ion channels

2005 • 3,667 citations

Activation of postsynaptically silent synapses during pairing-induced LTP in CA1 region of hippocampal slice

1995 • 1,342 citations

Quantitative Ultrastructural Analysis of Hippocampal Excitatory Synapses

1997 • 973 citations

Intracellular calcium dependence of transmitter release rates at a fast central synapse

2000 • 773 citations

Calcium dependence of the rate of exocytosis in a synaptic terminal

1994 • 746 citations

Patch-clamp techniques for time-resolved capacitance measurements in single cells

1988 • 659 citations

Calcium influx and transmitter release in a fast CNS synapse

1996 • 633 citations

High-frequency firing helps replenish the readily releasable pool of synaptic vesicles

1998 • 613 citations

Released Fraction and Total Size of a Pool of Immediately Available Transmitter Quanta at a Calyx Synapse

1999 • 607 citations

The exocytotic event in chromaffin cells revealed by patch amperometry

1997 • 555 citations

Calcium Sensitivity of Glutamate Release in a Calyx-Type Terminal

2000 • 511 citations

Fine-Tuning an Auditory Synapse for Speed and Fidelity: Developmental Changes in Presynaptic Waveform, EPSC Kinetics, and Synaptic Plasticity

2000 • 496 citations

Transporters Buffer Synaptically Released Glutamate on a Submillisecond Time Scale

1997 • 471 citations

Desensitization of AMPA receptors upon multiquantal neurotransmitter release

1993 • 471 citations

Kinetics of exocytosis and endocytosis at the cochlear inner hair cell afferent synapse of the mouse

2000 • 451 citations

Dynamics of synaptic vesicle fusion and membrane retrieval in synaptic terminals

1994 • 449 citations

Benzothiadiazides inhibit rapid glutamate receptor desensitization and enhance glutamatergic synaptic currents

1993 • 440 citations

Currents through the fusion pore that forms during exocytosis of a secretory vesicle

1987 • 432 citations

Pre‐ and postsynaptic whole‐cell recordings in the medial nucleus of the trapezoid body of the rat.

1995 • 429 citations

SYNAPTIC MECHANISMS FOR CODING TIMING IN AUDITORY NEURONS

1999 • 419 citations

Real-time measurements of vesicle-SNARE recycling in synapses of the central nervous system

2000 • 417 citations

The thickness, composition and structure of some lipid bilayers and natural membranes

1971 • 382 citations

Estimates for the pool size of releasable quanta at a single central synapse and for the time required to refill the pool.

1995 • 382 citations

Hippocampal neurons exhibit cyclothiazide-sensitive rapidly desensitizing responses to kainate

1993 • 369 citations

Variability of Neurotransmitter Concentration and Nonsaturation of Postsynaptic AMPA Receptors at Synapses in Hippocampal Cultures and Slices

1999 • 357 citations

Multivesicular release from excitatory synapses of cultured hippocampal neurons

1994 • 333 citations

Synaptic calcium transients in single spines indicate that NMDA receptors are not saturated

1999 • 321 citations

THE ROLE OF TIMING IN THE BRAIN STEM AUDITORY NUCLEI OF VERTEBRATES

1999 • 320 citations

The Reduced Release Probability of Releasable Vesicles during Recovery from Short-Term Synaptic Depression

1999 • 319 citations

Asynchronous release of synaptic vesicles determines the time course of the AMPA receptor-mediated EPSC

1995 • 310 citations

Evidence That Vesicles on the Synaptic Ribbon of Retinal Bipolar Neurons Can Be Rapidly Released

1996 • 297 citations

Techniques for Membrane Capacitance Measurements

1995 • 284 citations

R-type Ca ²⁺ currents evoke transmitter release at a rat central synapse

1998 • 273 citations

Non‐NMDA glutamate receptor occupancy and open probability at a rat cerebellar synapse with single and multiple release sites.

1996 • 266 citations

Ultrafast Exocytosis Elicited by Calcium Current in Synaptic Terminals of Retinal Bipolar Neurons

1996 • 259 citations

Calcium-triggered exocytosis and endocytosis in an isolated presynaptic cell: Capacitance measurements in saccular hair cells

1994 • 255 citations

Releasable pools and the kinetics of exocytosis in adrenal chromaffin cells

1994 • 254 citations

Pre‐ and postsynaptic glutamate receptors at a giant excitatory synapse in rat auditory brainstem slices.

1995 • 254 citations

Postfusional regulation of cleft glutamate concentration during LTP at ‘silent synapses’

2000 • 247 citations

Delayed clearance of transmitter and the role of glutamate transporters at synapses with multiple release sites

1996 • 235 citations

Calcium current during a single action potential in a large presynaptic terminal of the rat brainstem

1998 • 233 citations

The fine structure of nerve endings in the nucleus of the trapezoid body and the ventral cochlear nucleus

1966 • 227 citations

Nonsaturation of AMPA and NMDA receptors at hippocampal synapses

2000 • 219 citations

Direct Measurement of AMPA Receptor Desensitization Induced by Glutamatergic Synaptic Transmission

1996 • 209 citations

Very short-term plasticity in hippocampal synapses

1997 • 196 citations

Nerve Activity but Not Intracellular Calcium Determines the Time Course of Endocytosis at the Frog Neuromuscular Junction

1996 • 180 citations

Asynchronous transmitter release: control of exocytosis and endocytosis at the salamander rod synapse.

1996 • 163 citations

Submillisecond Kinetics of Glutamate Release from a Sensory Synapse

1998 • 162 citations

The binaural auditory pathway: excitatory amino acid receptors mediate dual timecourse excitatory postsynaptic currents in the rat medial nucleus of the trapezoid body

1993 • 159 citations

A Novel Presynaptic Inhibitory Mechanism Underlies Paired Pulse Depression at a Fast Central Synapse

1999 • 157 citations

Hippocampal synapses: do they talk to their neighbours?

1999 • 123 citations

Monitoring secretion in real time: capacitance, amperometry and fluorescence compared

1997 • 108 citations

ELECTROPHYSIOLOGY OF SYNAPTIC VESICLE CYCLING

1999 • 105 citations

Rapid exocytosis and endocytosis in nerve terminals of the rat posterior pituitary.

1996 • 102 citations

Postnatal Development of Phase-Locked High-Fidelity Synaptic Transmission in the Medial Nucleus of the Trapezoid Body of the Rat

1998 • 99 citations

Activity-related features of synapse morphology: A study of endbulbs of Held

1996 • 97 citations

Distribution and kinetics of membrane dielectric polarization. II. Frequency domain studies of gating currents.

1982 • 84 citations

The kinetics of quantal transmitter release from retinal amacrine cells.

1995 • 67 citations

Aging in the rat medial nucleus of the trapezoid Body. II. Electron microscopy

1985 • 53 citations

Static and Dynamic Membrane Properties of Large-Terminal Bipolar Cells From Goldfish Retina: Experimental Test of a Compartment Model

1997 • 48 citations

New structural features of synapses in the anteroventral cochlear nucleus prepared by direct freezing and freeze‐substitution

1989 • 48 citations

Broad specificity of GDNF family receptors GFR?1 and GFR?2 for GDNF and NTN in neurons and transfected cells

2000 • 26 citations

The Dynamic Range for Gain Control of NMDA Receptor-Mediated Synaptic Transmission at a Single Synapse

2000 • 17 citations