Physiology and molecular genetics of 17β-hydroxysteroid dehydrogenases

Williams Textbook of Endocrinology

2016 • 3,772 citations

A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes

1990 • 1,630 citations

A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation

1994 • 1,604 citations

Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene

1994 • 1,573 citations

Williams' Textbook of Endocrinology.

1991 • 1,248 citations

Male pseudohermaphroditism caused by mutations of testicular 17β–hydroxysteroid dehydrogenase 3

1994 • 561 citations

Expression cloning and characterization of human 17 beta-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20 alpha-hydroxysteroid dehydrogenase activity

1993 • 433 citations

Aromatization of Androstenedione by Human Adipose Tissue Stromal Cells in Monolayer Culture*

1981 • 395 citations

Mullerian Inhibiting Substance: A Gonadal Hormone with Multiple Functions*

1993 • 317 citations

Induction of Human Endometrial Estradiol Dehydrogenase by Progestins

1975 • 310 citations

Complete amino acid sequence of human placental 17β‐hydroxysteroid dehydrogenase deduced from cDNA

1988 • 298 citations

Characterization of cDNAs for Human Estradiol 17β-Dehydrogenase and Assignment of the Gene to Chromosome 17: Evidence of two mRNA Species with Distinct 5′-Termini in Human Placenta

1989 • 275 citations

Distribution of 17β-hydroxysteroid dehydrogenase gene expression and activity in rat and human tissues

1992 • 228 citations

Molecular cloning of a novel widely expressed human 80 kDa 17β-hydroxysteroid dehydrogenase IV

1995 • 211 citations

17 beta-Hydroxysteroid dehydrogenase type 2: chromosomal assignment and progestin regulation of gene expression in human endometrium.

1994 • 209 citations

Molecular genetics and pathophysiology of 17 beta-hydroxysteroid dehydrogenase 3 deficiency

1996 • 188 citations

Estradiol and 20α-Dihydroprogesterone Dehydrogenase Activities in Human Endometrium During the Menstrual Cycle

1974 • 177 citations

Structure of Two in Tandem Human 17β-Hydroxysteroid Dehydrogenase Genes

1990 • 176 citations

Familial Male Pseudohermaphroditism with Gynecomastia Due to a Testicular 17-Ketosteroid Reductase Defect. I. Studiesin Vivo

1971 • 172 citations

Sexual Differentiation

1978 • 156 citations

Immunological analysis of 17β‐hydroxysteroid dehydrogenase in benign and malignant human breast tissue

1992 • 116 citations

Furtherin VivoStudies in Male Pseudohermaphroditism with Gynecomastia Due to a Testicular 17-Ketosteroid Reductase Defect (Compared to a Case of Testicular Feminization)

1972 • 82 citations

Interleukin 6 is secreted by breast fibroblasts and stimulates 17β‐oestradiol oxidoreductase activity of MCF‐7 cells: Possible paracrine regulation of breast 17β‐oestradiol levels

1991 • 77 citations

Estrogen metabolism in normal and neoplastic endometrium

1977 • 71 citations

Stimulation of Various 17β and 20α-Hydroxysteroid Dehydrogenase Activities by Progestins in Human Endometrium*

1979 • 65 citations

17β-Hydroxysteroid dehydrogenase 3 deficiency

1996 • 64 citations

A soluble 17β-hydroxysteroid dehydrogenase from human placenta. The binding of pyridine nucleotides and steroids

1969 • 57 citations

MALE PSEUDOHERMAPHRODITISM WITH GYNAECOMASTIA DUE TO TESTICULAR 17‐KETOSTEROID REDUCTASE DEFICIENCY

1977 • 55 citations

17β-Hydroxysteroid dehydrogenase: isozymes and mutations

1995 • 51 citations

Mechanisms of androgen production in male pseudohermaphroditism due to 17 beta-hydroxysteroid dehydrogenase deficiency.

1992 • 49 citations

Isolation and sequencing of a complementary deoxyribonucleic acid clone encoding human placental 173-estradiol dehydrogenase: Identification of the putative cofactor binding site

1989 • 46 citations

Studies on 17beta-hydroxysteroid dehydrogenase in human endometrium and endometrial carcinoma I. Subcellular distribution and variations of specific enzyme activity.

1975 • 45 citations

STUDIES ON 17β-HYDROXYSTEROID DEHYDROGENASE IN HUMAN ENDOMETRIUM AND ENDOMETRIAL CARCINOMA

1975 • 40 citations

Testicular 17β-hydroxysteroid dehydrogenase: Molecular properties and reaction mechanism

1986 • 39 citations

Immunohistochemical study of the human 17β‐hydroxysteroid dehydrogenase and steroid receptors in endometrial adenocarcinoma

1992 • 36 citations

STUDIES ON 17β-HYDROXYSTEROID DEHYDROGENASE IN HUMAN ENDOMETRIUM AND ENDOMETRIAL CARCINOMA

1975 • 35 citations

Immunohistochemical study of the human 17β-hydroxysteroid dehydrogenase and steroid receptors in endometrial adenocarcinoma

1992 • 27 citations

Apparent immunologic nonidentity of human placental and endometrial 17β-estradiol dehydrogenase

1980 • 21 citations

Studies on 17 beta-hydroxysteroid dehydrogenase in human endometrium and endometrial carcinoma. III. Partial purification and characterization of the microsomal enzyme.

1975 • 16 citations

Mechanisms of androgen production in male pseudohermaphroditism due to 17 beta-hydroxysteroid dehydrogenase deficiency

1992 • 13 citations

STUDIES ON 17β-HYDROXYSTEROID DEHYDROGENASE IN HUMAN ENDOMETRIUM AND ENDOMETRIAL CARCINOMA

1975 • 8 citations