Structure of the C-terminal domain of Tup1, a corepressor of transcription in yeast

[20] Processing of X-ray diffraction data collected in oscillation mode

1997 • 33,348 citations

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1998 • 15,791 citations

NMRPipe: A multidimensional spectral processing system based on UNIX pipes

1995 • 15,623 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

Solvent content of protein crystals

1968 • 7,954 citations

The interpretation of protein structures: Estimation of static accessibility

1971 • 5,771 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

AMoRe: an automated package for molecular replacement

1994 • 4,990 citations

The ancient regulatory-protein family of WD-repeat proteins

1994 • 1,478 citations

The 2.0 Å crystal structure of a heterotrimeric G protein

1996 • 1,118 citations

The structure of the G protein heterotrimer Giα1β1γ2

1995 • 1,091 citations

Crystal structure of a GA protein βγdimer at 2.1 Å resolution

1996 • 741 citations

Ssn6-Tup1 is a general repressor of transcription in yeast

1992 • 680 citations

The DNA Replication and Damage Checkpoint Pathways Induce Transcription by Inhibition of the Crt1 Repressor

1998 • 514 citations

Control of Filament Formation in Candida albicans by the Transcriptional Repressor TUP1

1997 • 508 citations

A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast

1993 • 465 citations

Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4.

1996 • 460 citations

A functional interaction between the histone deacetylase Rpd3 and the corepressor Groucho in Drosophila development

1999 • 441 citations

A kinase–cyclin pair in the RNA polymerase II holoenzyme

1995 • 418 citations

Repetitive segmental structure of the transducin beta subunit: homology with the CDC4 gene and identification of related mRNAs.

1986 • 411 citations

Repression by SSN6-TUP1 is directed by MIG1, a repressor/activator protein.

1995 • 394 citations

Identification of a Mating Type-Like Locus in the Asexual Pathogenic Yeast Candida albicans

1999 • 354 citations

Cross-validated maximum likelihood enhances crystallographic simulated annealing refinement

1997 • 347 citations

Crystal Structure of a Free Radical Enzyme, Galactose Oxidase

1994 • 346 citations

Functional dissection of the yeast Cyc8–Tupl transcriptional co-repressor complex

1994 • 338 citations

Groucho proteins: transcriptional corepressors for specific subsets of DNA-binding transcription factors in vertebrates and invertebrates

1998 • 299 citations

Crystal Structure at 2.4 Å Resolution of the Complex of Transducin βγ and Its Regulator, Phosducin

1996 • 289 citations

Protein–protein interaction at crystal contacts

1995 • 261 citations

Distinct TPR motifs of Cyc8 are involved in recruiting the Cyc8-Tup1 corepressor complex to differentially regulated promoters.

1995 • 258 citations

Intragenic and extragenic suppressors of mutations in the heptapeptide repeat domain of Saccharomyces cerevisiae RNA polymerase II.

1989 • 250 citations

Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme.

1995 • 247 citations

The CYC8 and TUP1 proteins involved in glucose repression in Saccharomyces cerevisiae are associated in a protein complex.

1991 • 216 citations

The WD repeats of Tup1 interact with the homeo domain protein alpha 2.

1994 • 207 citations

Characterization of TUP1, a mediator of glucose repression in Saccharomyces cerevisiae.

1990 • 207 citations

Nucleosomes are positioned with base pair precision adjacent to the alpha 2 operator in Saccharomyces cerevisiae.

1991 • 203 citations

Halloween ... Masks and Bones

1994 • 202 citations

GENETICS OF TRANSCRIPTIONAL REGULATION IN YEAST: Connections to the RNA Polymerase II CTD

1997 • 202 citations

The global transcriptional regulators, SSN6 and TUP1, play distinct roles in the establishment of a repressive chromatin structure.

1994 • 190 citations

The Groucho/Transducin-like Enhancer of split Transcriptional Repressors Interact with the Genetically Defined Amino-terminal Silencing Domain of Histone H3

1997 • 149 citations

The Rox1 repressor of the Saccharomyces cerevisiae hypoxic genes is a specific DNA-binding protein with a high-mobility-group motif.

1993 • 142 citations

Ribbons.

1997 • 139 citations

The Cyc8 (Ssn6)-Tup1 Corepressor Complex Is Composed of One Cyc8 and Four Tup1 Subunits

1996 • 132 citations

Functional Relationships of Srb10-Srb11 Kinase, Carboxy-Terminal Domain Kinase CTDK-I, and Transcriptional Corepressor Ssn6-Tup1

1998 • 126 citations

Identification of genes required for alpha 2 repression in Saccharomyces cerevisiae.

1995 • 123 citations

Homeo Domain of the Yeast Repressor α2 Is a Sequence-Specific DNA-Binding Domain But Is Not Sufficient for Repression

1987 • 121 citations

A Role for Groucho Tetramerization in Transcriptional Repression

1998 • 119 citations

Nrg1 Is a Transcriptional Repressor for Glucose Repression ofSTA1Gene Expression inSaccharomyces cerevisiae

1999 • 110 citations

A Complex Composed of Tup1 and Ssn6 Represses Transcription in Vitro

1997 • 103 citations

Residues in the WD Repeats of Tup1 Required for Interaction with α2

1997 • 90 citations

The tetratricopeptide repeats of Ssn6 interact with the homeo domain of alpha 2.

1995 • 90 citations

Characterization of TUP1, a Mediator of Glucose Repression in Saccharomyces cerevisiae

1990 • 63 citations

Amino Termini of Histones H3 and H4 Are Required for a1-α2 Repression in Yeast

1997 • 50 citations

The Rox1 Repressor of the Saccharomyces cerevisiae Hypoxic Genes is a Specific DNA-Binding Protein with a High-Mobility-Group Motif

1993 • 46 citations

Characterization of the N-terminal Domain of the Yeast Transcriptional Repressor Tup1

2000 • 43 citations

Mutational Analysis of the Tup1 General Repressor of Yeast

1998 • 43 citations

Gene Regulation by the Yeast Ssn6-Tup1 Corepressor

1998 • 36 citations

The Anatomy of a Hypoxic Operator in Saccharomyces cerevisiae

1998 • 35 citations

Halloween ... Masks and Bones

1994 • 23 citations

Four hydrophobic amino acid residues in the C-terminal effector domain of the yeast Mig1p repressor are important for its in vivo activity

1998 • 14 citations

The WD repeats of Tup1 interact with the homeo domain protein α2

1995 • 3 citations