Lysophosphatidylcholine Promotes Cholesterol Efflux From Mouse Macrophage Foam Cells

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 21,307 citations

THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM

1955 • 8,846 citations

Beyond Cholesterol

1989 • 6,533 citations

Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology

1988 • 3,984 citations

Role of oxidized low density lipoprotein in atherogenesis.

1991 • 2,691 citations

High-Density Lipoprotein — The Clinical Implications of Recent Studies

1989 • 1,565 citations

Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts.

1976 • 1,032 citations

Inhibition of early atherogenesis in transgenic mice by human apolipoprotein AI

1991 • 990 citations

Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density lipoproteins

1990 • 871 citations

Cellular Cholesterol Efflux Mediated by Cyclodextrins

1995 • 864 citations

Lysophosphatidylcholine, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells.

1992 • 828 citations

Regression of atherosclerotic lesions by high density lipoprotein plasma fraction in the cholesterol-fed rabbit.

1990 • 767 citations

Plasma high density lipoproteins. Metabolism and relationship to atherogenesis.

1990 • 660 citations

Lysophosphatidylcholine: a chemotactic factor for human monocytes and its potential role in atherogenesis.

1988 • 655 citations

Procedure for determination of free and total cholesterol in micro- or nanogram amounts suitable for studies with cultured cells.

1978 • 561 citations

Lysophosphatidylcholine transcriptionally induces growth factor gene expression in cultured human endothelial cells.

1994 • 332 citations

Interaction of free apolipoproteins with macrophages. Formation of high density lipoprotein-like lipoproteins and reduction of cellular cholesterol.

1991 • 331 citations

Mouse macrophages synthesize and secrete a protein resembling apolipoprotein E.

1981 • 302 citations

Characterization of lipid-laden aortic cells from cholesterol-fed rabbits. IV. Investigation of macrophage-like properties of aortic cell populations.

1979 • 297 citations

Biochemical and genetic studies of the apoprotein E secreted by mouse macrophages and human monocytes.

1982 • 296 citations

Cellular pathology of progressive atherosclerosis in the WHHL rabbit. An animal model of familial hypercholesterolemia.

1983 • 282 citations

Hydrolysis and excretion of cytoplasmic cholesteryl esters by macrophages: stimulation by high density lipoprotein and other agents

1980 • 279 citations

Receptor-dependent hydrolysis of cholesteryl esters contained in plasma low density lipoprotein.

1975 • 210 citations

Lysophosphatidylcholine plays an essential role in the mitogenic effect of oxidized low density lipoprotein on murine macrophages.

1994 • 196 citations

Efflux of cellular cholesterol and phospholipid to lipid-free apolipoproteins and class A amphipathic peptides

1995 • 188 citations

Synthetic amphipathic helical peptides that mimic apolipoprotein A-I in clearing cellular cholesterol.

1994 • 187 citations

Lysophosphatidylcholine concentrations and metabolism in aortic intima plus inner media: effect of nutritionally induced atherosclerosis

1969 • 181 citations

Independent Pathways for Secretion of Cholesterol and Apolipoprotein E by Macrophages

1983 • 162 citations

Low Concentration of Oxidized Low-Density Lipoprotein and Lysophosphatidylcholine Upregulate Constitutive Nitric Oxide Synthase mRNA Expression in Bovine Aortic Endothelial Cells

1995 • 153 citations

Lysophosphatidylcholine increases vascular superoxide anion production via protein kinase C activation.

1994 • 139 citations

Lysophosphatidylcholine upregulates the level of heparin-binding epidermal growth factor-like growth factor mRNA in human monocytes.

1994 • 138 citations

Expression of heterologous human apolipoprotein E by J774 macrophages enhances cholesterol efflux to HDL3.

1994 • 135 citations

Lysophosphatidylcholine inhibits surface receptor-mediated intracellular signals in endothelial cells by a pathway involving protein kinase C activation.

1992 • 130 citations

Identification of foam cells in human atherosclerotic lesions as macrophages using monoclonal antibodies.

1985 • 122 citations

Transcriptional Induction of Endothelial Nitric Oxide Synthase Type III by Lysophosphatidylcholine

1995 • 113 citations

Reverse cholesterol transport: Physiology and pharmacology

1991 • 112 citations

Induction of cyclooxygenase-2 in human umbilical vein endothelial cells by lysophosphatidylcholine.

1995 • 88 citations

High density lipoprotein mediates selective reduction in cholesteryl esters from macrophage foam cells

1992 • 61 citations

Role of HDL Apolipoprotein E in Cellular Cholesterol Efflux: Studies in Apo E Knockout Transgenic Mice

1994 • 60 citations

Lysolecithins as endothelium-dependent vascular smooth muscle relaxants that differ from endothelium-derived relaxing factor (nitric oxide)

1988 • 51 citations

Oxidized LDL increase free cholesterol and fail to stimulate cholesterol esterification in murine macrophages

1990 • 51 citations

Elevated Levels of cAMP Inhibit Protein Kinase C– Independent Mechanisms of Endothelial Platelet-Derived Growth Factor–B Chain and Intercellular Adhesion Molecule-1 Gene Induction by Lysophosphatidylcholine

1995 • 34 citations

Post-transcriptional regulation of apolipoprotein E expression in mouse macrophages by phorbol ester

1993 • 20 citations

Probucol pretreatment enhances the chemotaxis of mouse peritoneal macrophages.

1992 • 9 citations

Exogenous Phospholipase C Specifically Inhibits ApoE Expression in Mouse Peritoneal Macrophages

1993 • 1 citations