Peroxisome Proliferator-Activated Receptor γ Induces Pancreatic Cancer Cell Apoptosis

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

1990 • 3,462 citations

15-Deoxy-Δ12,14-Prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ

1995 • 2,857 citations

A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation

1995 • 2,036 citations

Mechanism of Action of Fibrates on Lipid and Lipoprotein Metabolism

1998 • 1,690 citations

Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling

1992 • 1,514 citations

Adipogenesis and Obesity: Rounding Out the Big Picture

1996 • 1,268 citations

Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens

1980 • 854 citations

Ligands for peroxisome proliferator-activated receptorγ and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice

1998 • 807 citations

Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor γ and the retinoid X receptor

1997 • 655 citations

Activation of the peroxisome proliferator-activated receptor γ promotes the development of colon tumors in C57BL/6J-APCMin/+ mice

1998 • 612 citations

Ligand for peroxisome proliferator-activated receptor gamma (troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo.

1998 • 599 citations

Activators of the nuclear receptor PPARγ enhance colon polyp formation

1998 • 585 citations

Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-γ ligand troglitazone in patients with liposarcoma

1999 • 501 citations

Endothelial Cell Apoptosis Induced by the Peroxisome Proliferator-activated Receptor (PPAR) Ligand 15-Deoxy-Δ12,14-prostaglandin J2

1999 • 440 citations

Effects of ligand activation of peroxisome proliferator-activated receptor γ in human prostate cancer

2000 • 430 citations

Biochemical Mechanisms Of Induction Of Hepatic Peroxisome Proliferation

1989 • 356 citations

Inhibition of Human Lung Cancer Cell Growth by the Peroxisome Proliferator-Activated Receptor-γ Agonists through Induction of Apoptosis

2000 • 329 citations

Novel Sequence Determinants in Peroxisome Proliferator Signaling

1995 • 285 citations

Influence of J series prostaglandins on apoptosis and tumorigenesis of breast cancer cells

1999 • 183 citations

Expression of Peroxisome Proferator-Activated Receptor γ (PPARγ) in Human Transitional Bladder Cancer and its Role in Inducing Cell Death

1999 • 175 citations

The nuclear receptor PPARγ-bigger than fat

1998 • 141 citations

PPARγ in Monocytes: Less Pain, Any Gain?

1998 • 139 citations

15-Deoxy-Δ12,14-prostaglandin J2, a Ligand for Peroxisome Proliferator-Activated Receptor-γ, Induces Apoptosis in JEG3 Choriocarcinoma Cells

1999 • 119 citations

Expression of peroxisome proliferator-activated receptors (PPARS) in human astrocytic cells: PPAR? agonists as inducers of apoptosis

2000 • 108 citations

Apoptosis induction and cyclooxygenase-2 regulation in human colorectal adenoma and carcinoma cell lines by the cyclooxygenase-2-selective non-steroidal anti-inflammatory drug NS-398

2000 • 99 citations

PPARgamma ligand (thiazolidinedione) induces growth arrest and differentiation markers of human pancreatic cancer cells.

2000 • 71 citations

Peroxisome proliferator-activated receptor gamma activation in human breast cancer.

1999 • 39 citations

PPARγ Inhibits the Expression of c-MET in Human Gastric Cancer Cells through the Suppression of Ets

1999 • 39 citations

15-deoxy-Δ12,14PGJ2 induces diverse biological responses via PPARγ activation in cancer cells

2000 • 38 citations