Structure and phosphorylation of eukaryotic initiation factor 2. Casein kinase 2 and protein kinase C phosphorylate distinct but adjacent sites in the β-subunit

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

1977 • 5,640 citations

Processing of Adenovirus 2-Induced Proteins

1973 • 762 citations

Studies on the phosphorylation of myelin basic protein by protein kinase C and adenosine 3‘:5‘-monophosphate-dependent protein kinase.

1985 • 426 citations

Initiation of protein synthesis in mammalian cells

1986 • 359 citations

The influence of basic residues on the substrate specificity of protein kinase C.

1987 • 287 citations

Purification to homogeneity of protein kinase C from bovine brain-identity with the phorbol ester receptor.

1984 • 283 citations

Heat shock-induced translational alterations in HeLa cells. Initiation factor modifications and the inhibition of translation.

1984 • 282 citations

Substrate specificity of a multifunctional calmodulin-dependent protein kinase.

1985 • 243 citations

Regulation of protein synthesis initiation in eucaryotes

1983 • 227 citations

Purification of the eukaryotic initiation factor 2-eukaryotic initiation factor 2B complex and characterization of its guanine nucleotide exchange activity during protein synthesis initiation.

1983 • 203 citations

Phosphorylation of the Type‐II Regulatory Subunit of Cyclic‐AMP‐Dependent Protein Kinase by Glycogen Synthase Kinase 3 and Glycogen Synthase Kinase 5

1982 • 184 citations

Endogenous phosphate acceptor proteins for rat liver cytosolic casein kinases.

1981 • 153 citations

Synthetic peptides including acidic clusters as substrates and inhibitors of rat liver casein kinase TS (type-2).

1984 • 137 citations

Structure and regulation of eukaryotic initiation factor eIF-2. Sequence of the site in the alpha subunit phosphorylated by the haem-controlled repressor and by the double-stranded RNA-activated inhibitor

1987 • 129 citations

Guanine nucleotides, protein phosphorylation and the control of translation

1986 • 124 citations

Evidence that insulin activates fat-cell acetyl-CoA carboxylase by increased phosphorylation at a specific site

1982 • 117 citations

The Hormonal Control of Activity of Skeletal Muscle Phosphorylase Kinase

1975 • 107 citations

Distinct structural requirements of Ca²⁺/phospholipid‐dependent protein kinase (protein kinase C) and cAMP‐dependent protein kinase as evidenced by synthetic peptide substrates

1985 • 103 citations

The phosphorylation of eukaryotic ribosomal protein S6 by protein kinase C

1985 • 91 citations

A Reinvestigation of the Phosphorylation of Rabbit Skeletal‐Muscle Glycogen Synthase by Cyclic‐AMP‐Dependent Protein Kinase

1981 • 77 citations

Phosphorylation in vitro of eukaryotic initiation factors IF-E2 and IF-E3 by protein kinases.

1976 • 76 citations

Site-specific phosphorylation if initiation factor 2 by three cyclic nucleotide-independent protein kinases.

1980 • 71 citations

Protein kinase C: Rapid enzyme purification and substrate-dependence of the diacylglycerol effect

1984 • 70 citations

Ca2+-independent activation of protease-activated kinase II by phospholipids/diolein and comparison with the Ca2+/phospholipid-dependent protein kinase.

1986 • 56 citations

Purification and characterization of eukaryotic initiation factor 2 and a guanine nucleotide exchange factor from rat liver.

1987 • 56 citations

Phospholipid‐sensitive Ca²⁺‐dependent protein kinase phosphorylates the β subunit of eukaryotic initiation factor 2 (eIF‐2)

1983 • 51 citations

Phosphorylation of glycogen synthase and of the beta subunit of eukaryotic initiation factor two by a common protein kinase.

1981 • 48 citations

Protein synthesis in rabbit reticulocytes. A study of peptide chain initiation using native and beta-subunit-depleted eukaryotic initiation factor 2.

1982 • 42 citations

Coping with a growing family

1987 • 40 citations

The NH2-terminal sequence of the alpha and gamma subunits of eukaryotic initiation factor 2 and the phosphorylation site for the heme-regulated eIF-2 alpha kinase.

1986 • 40 citations

The Role of Phosphorylation in the Regulation of Eukaryotic Initiation Factor 2 Activity

1982 • 32 citations

Purification and phosphorylation of initiation factor eIF‐2 from rabbit skeletal muscle

1982 • 30 citations

Regulation of binding of initiator tRNA to eukaryotic initiation factor eIF‐2

1982 • 24 citations

Eukaryotic initiation factor 2 from rat liver: no apparent function for the β-subunit in the formation of initiation complexes

1986 • 24 citations

Rabbit liver glycogen synthase kinases. Characterization of a protein kinase (PC0.7) able to phosphorylate glycogen synthase and phosvitin.

1982 • 20 citations

Phosphorylation by protein kinase C of a synthetic heptapeptide bearing a lysine residue on the C terminal side of serine

1987 • 10 citations

Epidermal growth factor, but not insulin, stimulates tyrosine phosphorylation of an endogenous protein of Mr 95,000 in triton extracts of human placental syncytiotrophoblast membranes

1987 • 9 citations