Evidence that insulin activates fat-cell acetyl-CoA carboxylase by increased phosphorylation at a specific site

Acute effects in vivo of anti-insulin serum on rates of fatty acid synthesis and activities of acetyl-coenzyme A carboxylase and pyruvate dehydrogenase in liver and epididymal adipose tissue of fed rats

1976 • 357 citations

Sites of phosphorylation on pyruvate dehydrogenase from bovine kidney and heart

1978 • 283 citations

Acetyl coenzyme A carboxylase.

1974 • 216 citations

A partial view of the mechanism of insulin action

1981 • 215 citations

The Purification and Properties of Rabbit Skeletal Muscle Glycogen Synthase

1976 • 196 citations

Insulin and the regulation of adipose-tissue acetyl-coenzyme A carboxylase

1973 • 184 citations

Recently discovered systems of enzyme regulation by reversible phosphorylation

1980 • 156 citations

Identification of ATP citrate lyase as a phosphoprotein.

1979 • 149 citations

Regulation of hepatic acetyl coenzyme A carboxylase by insulin and glucagon.

1979 • 147 citations

Evidence that fatty acid synthesis in the interscapular brown adipose tissue of cold-adapted rats is increased in vivo by insulin by mechanisms involving parallel activation of pyruvate dehydrogenase and acetyl-coenzyme A carboxylase

1977 • 138 citations

Insulin-stimulated protein phosphorylation in 3T3-L1 preadipocytes.

1979 • 133 citations

Inhibition of Rat-Liver Acetyl-Coenzyme-A Carboxylase by Palmitoyl-Coenzyme A. Formation of Equimolar Enzyme-Inhibitor Complex

1978 • 126 citations

Reversible Phosphorylation and Inactivation of Acetyl‐CoA Carboxylase from Lactating Rat Mammary Gland by Cyclic AMP‐Dependent Protein Kinase

1980 • 111 citations

Purification of a hepatic 123,000-dalton hormone-stimulated 32P-peptide and its identification as ATP-citrate lyase.

1979 • 109 citations

Short‐term effects of insulin and glucagon on lipid synthesis in isolated rat hepatocytes

1978 • 106 citations

Actions of insulin, epinephrine, and dibutyryl adenosine cyclic 5'-monophosphate on fat cell protein phosphorylations. Adenosine cyclic 5'-monophosphate dependent and independent mechanisms

1975 • 105 citations

Hormonal regulation of adipose-tissue acetyl-coenzyme A carboxylase by changes in the polymeric state of the enzyme. The role of long-chain fatty acyl-coenzyme A thioesters and citrate

1974 • 104 citations

Glucagon regulation of protein phosphorylation. Identification of acetyl coenzyme A carboxylase as a substrate.

1979 • 104 citations

Acetyl Coenzyme A Carboxylase from Rat Liver

1972 • 102 citations

Insulin-treated 3T3-L1 adipocytes and cell-free extracts derived from them incorporate 32P into ribosomal protein S6.

1980 • 98 citations

Adrenaline and the regulation of acetyl-coenzyme A carboxylase in rat epididymal adipose tissue. Inactivation of the enzyme is associated with phosphorylation and can be reversed on dephosphorylation

1979 • 97 citations

Regulation of pig heart pyruvate dehydrogenase by phosphorylation. Studies on the subunit and phosphorylation stoicheiometries

1978 • 93 citations

Regulation of rat liver acetyl coenzyme A carboxylase. Evidence for interconversion between active and inactive forms of enzyme by phosphorylation and dephosphorylation.

1977 • 87 citations

Effects of glucagon and insulin on cytoplasmic protein phosphorylation in hepatocytes

1978 • 82 citations

HeLa ribosomal protein S6. Insulin and dibutyryl cyclic AMP affect different phosphopeptides.

1981 • 77 citations

The regulation of fatty acid biosynthesis

1978 • 73 citations

Fat cell protein phosphorylation. Identification of phosphoprotein-2 as ATP-citrate lyase.

1979 • 71 citations

Incorporation of 32Pi into pyruvate dehydrogenase phosphate in mitochondria from control and insulin-treated adipose tissue

1976 • 63 citations

Studies on the incorporation of [32P]phosphate into pyruvate dehydrogenase in intact rat fat-cells. Effects of insulin

1980 • 61 citations

Dephosphorylation and activation of Acetyl‐CoA‐carboxylase from lactating rabbit mammary gland

1979 • 59 citations

Demonstration of the phosphorylation of acetyl-coenzyme A carboxylase within intact rat epididymal fat-cells

1977 • 56 citations

Purification and Physicochemical Properties of Fatty Acid Synthetase and Acetyl‐CoA Carboxylase from Lactating Rabbit Mammary Gland

1978 • 56 citations

Regulation of rat liver acetyl-CoA carboxylase. Stimulation of phosphorylation and subsequent inactivation of liver acetyl-CoA carboxylase by cyclic 3‘:5‘-monophosphate and effect on the structure of the enzyme.

1978 • 56 citations

Stimulation by epinephrine of in vivo phosphorylation and inactivation of acetyl coenzyme A carboxylase of rat epididymal adipose tissue.

1979 • 54 citations

Hormonal regulation of acetyl CoA carboxylase effect of insulin and epinephrine

1973 • 52 citations

Insulin stimulates the phosphorylation of acetyl-CoA carboxylase

1981 • 51 citations

Regulation of acetyl‐CoA carboxylase: identity of sites phosphorylated in intact cells treated with adrenaline and in vitro by cyclic AMP‐dependent protein kinase

1980 • 50 citations

A stimulatory effect of insulin on phosphorylation of a peptide in sarcolemma‐enriched membrane preparation from rat skeletal muscle

1977 • 44 citations

Anti-insulin receptor antibodies mimic the effects of insulin on the activities of pyruvate dehydrogenase and acetylCoA carboxylase and on specific protein phosphorylation in rat epididymal fat cells

1980 • 42 citations

Coenzyme A activation of acetyl-CoA carboxylase.

1981 • 40 citations

Phosphorylation of ATP-citrate lyase by a cyclic AMP-independent protein kinase from a rat liver

1981 • 37 citations

The effect of insulin and adrenaline on the phosphorylation of a 22000-molecular weight protein within isolated fat cells; possible identification as the inhibitor-1 of the ‘general phosphatase’

1980 • 35 citations

Evidence for phosphorylation and activation of acetyl CoA carboxylase by a membrane‐associated cyclic AMP‐independent protein kinase

1981 • 34 citations

Effect of epinephrine on acetyl-CoA carboxylase in rat epididymal fat tissue.

1978 • 33 citations

A new method for the isolation of rat liver acetyl-CoA carboxylase.

1981 • 30 citations

Dephosphorylation and activation of Acetyl-CoA carboxylase by phosphorylase phosphatase

1980 • 26 citations

The effect of insulin and guanosine nucleotides on protein phosphorylations by sarcolemma membranes from skeletal muscle

1979 • 25 citations

Absorption of antisera for studies on specific enzyme turnover

1976 • 17 citations

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