Phosphoinositide Binding Regulates α-Actinin Dynamics

PTEN , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

1997 • 4,753 citations

Role of Phosphoinositide 3-OH Kinase in Cell Transformation and Control of the Actin Cytoskeleton by Ras

1997 • 1,064 citations

The lamellipodium: where motility begins

2002 • 913 citations

Phosphoinositide Regulation of the Actin Cytoskeleton

2003 • 644 citations

Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation.

1996 • 568 citations

PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G ₁ cell cycle arrest in human glioblastoma cells

1998 • 480 citations

Type Iγ phosphatidylinositol phosphate kinase targets and regulates focal adhesions

2002 • 436 citations

The structure and function of α-actinin

1989 • 421 citations

α‐actinin revisited: A fresh look at an old player

2004 • 412 citations

Force-dependent integrin-cytoskeleton linkage formation requires downregulation of focal complex dynamics by Shp2

2003 • 216 citations

Regulation of focal complex composition and disassembly by the calcium-dependent protease calpain

2002 • 206 citations

Simultaneous Stretching and Contraction of Stress Fibers In Vivo

2004 • 191 citations

Dissecting the link between stress fibres and focal adhesions by CALI with EGFP fusion proteins

2002 • 187 citations

alpha-Actinin and vinculin are PIP2-binding proteins involved in signaling by tyrosine kinase.

1994 • 186 citations

Analysis of the actin-binding domain of alpha-actinin by mutagenesis and demonstration that dystrophin contains a functionally homologous domain.

1992 • 182 citations

Mapping in vivo associations of cytoplasmic proteins with integrin beta 1 cytoplasmic domain mutants.

1995 • 136 citations

Dynamics of ?-actinin in focal adhesions and stress fibers visualized with ?-actinin-green fluorescent protein

2001 • 135 citations

CRP1, a LIM Domain Protein Implicated in Muscle Differentiation, Interacts with α-Actinin

1997 • 131 citations

Restructuring of Focal Adhesion Plaques by Pi 3-Kinase

2000 • 127 citations

Regulating integrin-mediated adhesion: one more function for PI 3-kinase?

1996 • 115 citations

α-Actinin: a direct link between actin and integrins

1991 • 102 citations

Syndecan-4 Associates with α-Actinin

2003 • 97 citations

Phosphoinositide Binding Inhibits α-Actinin Bundling Activity

2003 • 93 citations

Microfilament‐dependent movement of the β3 integrin subunit within focal contacts of endothelial cells

2002 • 69 citations

Integrin-mediated Activation of Focal Adhesion Kinase Is Independent of Focal Adhesion Formation or Integrin Activation

1997 • 67 citations

Intracellular Movement of Green Fluorescent Protein–Tagged Phosphatidylinositol 3-Kinase in Response to Growth Factor Receptor Signaling

1999 • 62 citations

Phosphoinositides differentially regulate alpha-actinin flexibility and function

2004 • 56 citations

Revealing Protein Dynamics by Photobleaching Techniques

2004 • 17 citations