Tissue-specific DNase I hypersensitive sites in a foreign globin gene in transgenic mice

Chromosomal Subunits in Active Genes Have an Altered Conformation

1976 • 1,842 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

Determination of nucleic acid sequence homologies and relative concentrations by a dot hybridization procedure

1979 • 1,403 citations

The 5′ ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase I

1980 • 1,114 citations

DNA methylation affects the formation of active chromatin

1986 • 588 citations

Tissue-specific DNA cleavages in the globin chromatin domain introduced by DNAase I

1980 • 486 citations

An altered DNA conformation detected by S1 nuclease occurs at specific regions in active chick globin chromatin

1982 • 448 citations

A 200 base pair region at the 5$prime; end of the chicken adult $beta;-globin gene is accessible to nuclease digestion

1981 • 443 citations

Erythroid-specific expression of human beta-globin genes in transgenic mice.

1985 • 436 citations

DNAase I-hypersensitive sites of chromatin

1981 • 410 citations

α-globin-gene switching during the development of chicken embryos: Expression and chromosome structure

1981 • 353 citations

Differences in human α- and β-globin gene expression in mouse erythroleukemia cells: The role of intragenic sequences

1984 • 312 citations

A dominant role for DNA secondary structure in forming hypersensitive structures in chromatin

1983 • 273 citations

SELECTED TOPICS IN CHROMATIN STRUCTURE

1985 • 253 citations

A foreign β-globin gene in transgenic mice: Integration at abnormal chromosomal positions and expression in inappropriate tissues

1983 • 245 citations

Specific expression of a foreign β-globin gene in erythroid cells of transgenic mice

1985 • 235 citations

Regulated expression of human growth hormone genes in mouse cells

1982 • 219 citations

Developmental regulation of a cloned adult β-globin gene in transgenic mice

1985 • 215 citations

An embryonic pattern of expression of a human fetal globin gene in transgenic mice

1986 • 204 citations

The definition of a large viral transcription unit late in Ad2 infection of HeLa cells: Mapping of nascent RNA molecular labeled in isolated nuclei

1977 • 198 citations

Human fetal to adult hemoglobin switching: changes in chromatin structure of the beta-globin gene locus.

1983 • 190 citations

Hb switching in chickens

1980 • 189 citations

Propagation of globin DNAase i-hypersensitive sites in absence of factors required for induction: A possible mechanism for determination

1982 • 189 citations

The regulated expression of β-globin genes introduced into mouse erythroleukemia cells

1983 • 186 citations

Globin RNA transcription: A possible termination site and demonstration of transcriptional control correlated with altered chromatin structure

1982 • 144 citations

Nucleosomes are phased along the mouse β-major globin gene in erythroid and nonerythroid cells

1986 • 119 citations

Murine erythroleukemia cell differentiation: DNase I hypersensitivity and DNA methylation near the globin genes

1982 • 110 citations

Gene expression in murine erythroleukemia cells

1984 • 78 citations

Nucleosome disruption precedes transcription and is largely limited to the transcribed domain of globin genes in murine erythroleukemia cells

1985 • 76 citations

Developmental Regulation of Human Globin Genes in Transgenic Mice

1985 • 74 citations

Increase in the accumulation of globin mRNA in immature erythroblasts in response to erythropoietin in vivo or in vitro

1975 • 31 citations

Sequential alterations in globin gene chromatin structure during erythroleukemia cell differentiation.

1985 • 25 citations