Hyperbilirubinemia and cholestasis

The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase.

1968 • 1,767 citations

Glutathione: Metabolism and function

1978 • 971 citations

A Binding Protein for Fatty Acids in Cytosol of Intestinal Mucosa, Liver, Myocardium, and Other Tissues

1972 • 713 citations

Two hepatic cytoplasmic protein fractions, Y and Z, and their possible role in the hepatic uptake of bilirubin, sulfobromophthalein, and other anions

1969 • 589 citations

Congenital familial nonhemolytic jaundice with kernicterus.

1952 • 541 citations

The Identity of Glutathione S -Transferase B with Ligandin, a Major Binding Protein of Liver

1974 • 491 citations

The liver: quantitative aspects of structure and function

1973 • 369 citations

Chronic nonhemolytic unconjugated hyperbilirubinemia with glucuronyl transferase deficiency

1969 • 332 citations

[Drugs and the liver].

1970 • 278 citations

Hepatic Bilirubin UDP-Glucuronyl Transferase Activity in Liver Disease and Gilbert's Syndrome

1969 • 274 citations

ON THE ORIGIN OF BILE PIGMENT IN NORMAL MAN

1950 • 260 citations

Hepatic organic anion uptake in the rat.

1975 • 250 citations

Effect of sodium taurolithocholate on bile flow and bile acid excretion

1968 • 247 citations

Studies of bilirubin kinetics in normal adults

1969 • 235 citations

Metabolic Effects of Gonadal Hormones and Contraceptive Steroids

1969 • 235 citations

The effect of estrogen on bile formation in the rat

1969 • 167 citations

Initial distribution and rate of uptake of sulfobromophthalein in the liver

1964 • 164 citations

Constitutional hepatic dysfunction (Gilbert's syndrome)

1970 • 159 citations

Determination of bilirubin UDP-glucuronyl transferase activity in needle-biopsy specimens of human liver

1970 • 155 citations

Studies in congenital porphyria. 2. Incorporation of 15N in the stercobilin in the normal and in the porphyric

1950 • 141 citations

THE PROTEIN-BINDING OF C14-BILIRUBIN IN HUMAN AND MURINE SERUM*

1963 • 140 citations

Bilirubin conjugates in bile of man and rat in the normal state and in liver disease

1972 • 130 citations

Trihydroxycoprostanic acid in the duodenal fluid of two children with intrahepatic bile duct anomalies

1972 • 127 citations

Bile Acid Metabolism in Health and Disease

1978 • 123 citations

Excretion of 3β‐hydroxy‐5‐cholenoic and 3a‐hydroxy‐5a‐cholanoic acids in urine of infants with biliary atresia

1971 • 121 citations

The metabolism of 3alpha, 7alpha, 12alpha-trihydorxy-5beta-cholestan-26-oic acid in two siblings with cholestasis due to intrahepatic bile duct anomalies. An apparent inborn error of cholic acid synthesis.

1975 • 119 citations

Duncan's Diseases of Metabolism

1970 • 119 citations

Identification and characterization of a bile acid receptor in isolated liver surface membranes.

1976 • 114 citations

Enhanced formation of rapidly labeled bilirubin by phenobarbital: Hepatic microsomal cytochromes as a possible source

1966 • 105 citations

Bile Salt Glucuronides: Identification and Quantitative Analysis in the Urine of Patients with Cholestasis

1976 • 104 citations

Measurement of sulfated and nonsulfated bile acids in human serum and urine

1974 • 102 citations

Abnormal Hepatic Transport of Indocyanine Green in Gilbert's Syndrome

1976 • 99 citations

Rotor's syndrome

1976 • 96 citations

Defective Bromosulfophthalein Clearance in Patients with Constitutional Hepatic Dysfunction (Gilbert's Syndrome)

1972 • 96 citations

Scanning Electron Microscopy of the Rat Liver

1975 • 90 citations

Evaluation of fluorimetrically estimated serum bile acid in liver disease

1977 • 89 citations

Sulfated Bile Acids in Germ‐Free and Conventional Mice

1976 • 88 citations

Subcellular pathology of rat liver in cholestasis and choleresis induced by bile salts. 1. Effects of lithocholic, 3beta-hydroxy-5-cholenoic, cholic, and dehydrocholic acids.

1977 • 86 citations

Identification of 3β-Hydroxy-5-cholenoic Acid in Human Meconium

1973 • 72 citations

Bile acid metabolism in health and disease.

1979 • 69 citations

THE PLASMA REMOVAL OF INDOCYANINE GREEN AND SULFOBROMOPHTHALEIN: EFFECT OF DOSAGE AND BLOCKING AGENTS

1961 • 69 citations

The nonerythropoietic component of early bilirubin

1968 • 67 citations

THE HEPATIC UPTAKE AND EXCRETION OF SULFOBROMOPHTHALEIN AND BILIRUBIN.

1965 • 66 citations

Abnormal Excretion of the Isomers of Urinary Coproporphyrin by Patients with Dubin—Johnson Syndrome in Israel

1971 • 62 citations

Hepatic Bile Formation

1976 • 62 citations

Bile acid excretion: the alternate pathway in the hamster.

1977 • 61 citations

Hepatic intracellular distribution of tritium-labeled unconjugated and conjugated bilirubin in normal and Gunn rats.

1966 • 60 citations

Disorders of Bilirubin Metabolism

1972 • 60 citations

Conversion of Cholesterol to Trihydroxycoprostanic Acid and Cholic Acid in Man*

1964 • 53 citations

A new approach to quantitation of the various sources of bilrubin in man.

1976 • 52 citations

THE IMPORTANCE OF THE FRACTIONAL SERUM BILIRUBIN DETERMINATION IN CLINICAL MEDICINE

1956 • 44 citations

Serum bile acid analysis: a rapid, direct enzymatic method using dual-beam spectrophotofluorimetry

1977 • 43 citations

ROLE OF HEPATIC ANION-BINDING PROTEIN IN BROMSULPHTHALEIN CONJUGATION

1973 • 43 citations

Drugs and the liver—I

1974 • 42 citations

Bile acid synthesis in man. II. Determination of 7 α-hydroxycholesterol, (22R)-22-hydroxycholesterol, and 26-hydroxycholesterol in human meconium

1977 • 40 citations

Influence of Albumin on the Hepatic Uptake of Unconjugated Bilirubin

1973 • 37 citations

Quantitative studies of the delivery of hepatic-synthesized bilirubin to plasma utilizing δ-aminolevulinic acid-4-14C and bilirubin-3H in man

1972 • 36 citations

Inheritance of type 2 Crigler-Najjar hyperbilirubinaemia

1973 • 35 citations

Chronic Hyperbilirubinemia Associated with Hepatic Uptake and Storage Impairment

1975 • 35 citations

Inborn Errors of Bilirubin Metabolism

1975 • 31 citations

Liver and Bile

1932 • 29 citations

Chronic hyperbilirubinemia associated with hepatic uptake and storage impairment. A new syndrome resembling that of the mutant Southdown sheep.

1975 • 28 citations

Studies of Hepatic Excretory Function

1967 • 28 citations

Studies of hepatic excretory function. IV. Biliary excretion of sulfobromophthalein sodium in a patient with the Dubin-Johnson syndrome and a biliary fistula.

1968 • 24 citations

Increased bilirubin formation from nonhemoglobin sources in rats with disorders of the liver.

1969 • 20 citations

Studies of the kinetics of purified conjugated bilirubin-3H in the rat.

1978 • 19 citations

Direct Serum Bilirubin and the Sulfobromophthalein Test in Occult Liver Disease

1967 • 14 citations

Excretion of Monohydroxy Bile Acid Ester Sulfates in the Rat

2015 • 12 citations

Hepatic clearance of unconjugated bilirubin in cholestatic liver diseases

1974 • 9 citations

On the Structure and Function of Ligandin and Z Protein

1976 • 6 citations

Fluorescence Spectroscopy: Finally of Interest

1976 • 3 citations