Hepatic Bile Formation

The Fluid Mosaic Model of the Structure of Cell Membranes

1972 • 8,835 citations

Coupled transport of sodium and organic solutes.

1970 • 1,175 citations

Standing-Gradient Osmotic Flow

1967 • 828 citations

The theory of measurement of osmotic pressure

1951 • 537 citations

Water transport in cells and tissues

1974 • 375 citations

Subdivision of hexagonal liver lobules into a structural and functional unit. Role in hepatic physiology and pathology

1954 • 371 citations

Inhibition of water and solute permeability in human red cells

1970 • 358 citations

THE RATE OF EXCHANGE OF TRITIATED WATER ACROSS THE HUMAN RED CELL MEMBRANE

1957 • 340 citations

Na, Cl, and Water Transport by Rat Ileum in Vitro

1960 • 337 citations

FLUID TRANSPORT IN THE RABBIT GALLBLADDER

1966 • 319 citations

The microcirculatory hepatic unit

1973 • 317 citations

On the Uptake of Materials by the Intact Liver. THE TRANSPORT AND NET REMOVAL OF GALACTOSE

1973 • 295 citations

Size and Structure of Bile Salt Micelles

1968 • 269 citations

Secretion of organic anions in the formation of urine and bile.

1959 • 262 citations

Hepatic organic anion uptake in the rat.

1975 • 250 citations

Effect of sodium taurolithocholate on bile flow and bile acid excretion

1968 • 247 citations

Water Permeability of Thin Lipid Membranes

1967 • 246 citations

A dynamic and static study of hepatic arterioles and hepatic sphincters

1966 • 228 citations

Mechanism of phenobarbital-induced hypercholeresis in the rat

1970 • 209 citations

Canalicular bile production in dogs

1968 • 209 citations

Factors affecting the relative magnitudes of the sodium: potassium and sodium: sodium exchanges catalysed by the sodium pump

1967 • 196 citations

Sodium chloride transport by rabbit gallbladder. Direct evidence for a coupled NaCl influx process.

1975 • 195 citations

Effect of inhibitors of sodium transport on bile formation in the rabbit

1970 • 169 citations

The effect of estrogen on bile formation in the rat

1969 • 167 citations

THE RELATIONSHIP BETWEEN TAUROCHOLATE SECRETION RATE AND BILE PRODUCTION IN THE UNANESTHETIZED DOG DURING CHOLINERGIC BLOCKADE AND DURING SECRETIN ADMINISTRATION*

1962 • 157 citations

Factors determining the maximal rate of organic anion secretion by the liver and further evidence on the hepatic site of action of the hormone secretin

1966 • 149 citations

Mechanics of Bile Secretion

1954 • 141 citations

Structure and function in red cell permeability

1956 • 140 citations

Byler's disease: Fatal intrahepatic cholestasis

1972 • 134 citations

Trihydroxycoprostanic acid in the duodenal fluid of two children with intrahepatic bile duct anomalies

1972 • 127 citations

Excretion of 3β‐hydroxy‐5‐cholenoic and 3a‐hydroxy‐5a‐cholanoic acids in urine of infants with biliary atresia

1971 • 121 citations

The metabolism of 3alpha, 7alpha, 12alpha-trihydorxy-5beta-cholestan-26-oic acid in two siblings with cholestasis due to intrahepatic bile duct anomalies. An apparent inborn error of cholic acid synthesis.

1975 • 119 citations

Identification and characterization of a bile acid receptor in isolated liver surface membranes.

1976 • 114 citations

Relationship between the Biliary Excretion of Bile Acids and the Excretion of Water, Lecithin, and Cholesterol in Man

1971 • 106 citations

Studies on the Transport and Metabolism of Conjugated Bile Salts by Intestinal Mucosa *

1964 • 99 citations

Biliary excretion of inulin, sucrose, and mannitol: analysis of bile formation

1961 • 90 citations

Scanning Electron Microscopy of the Rat Liver

1975 • 90 citations

Mechanisms of Bile Acid Biosynthesis

1973 • 82 citations

Identification of 3β-Hydroxy-5-cholenoic Acid in Human Meconium

1973 • 72 citations

What Retains Water in Living Cells?

1976 • 68 citations

Morphologic changes in hamster liver during intrahepatic cholestasis induced by taurolithocholate.

1966 • 66 citations

Bile formation in guinea pigs: analysis with inert solutes of graded molecular radius

1968 • 64 citations

Acute cholestasis induced by lithocholic acid in the rat. A freeze-fracture replica and thin section study.

1975 • 61 citations

The Enhancement of Maximal Bilirubin Excretion with Taurocholate–Induced Increments in Bile Flow

1974 • 56 citations

Hydrocortisone choleresis in the dog

1970 • 52 citations

Choleresis and hepatic transport mechanisms

1975 • 44 citations

Phenol 3, 6 Dibromphthalein Disulfonate, A New Compound for the Study of Liver Disease

1964 • 42 citations

Does bile acid secretion determine canalicular bile production in rats?

1971 • 40 citations

Effect of Phenobarbital on the Ethynyl Estradiol-Induced Cholestasis in the Rat

1973 • 38 citations

Bilirubin transport by liver in adult Macaca mulatta

1971 • 36 citations

Influence of Cholic and Chenodeoxycholic Acid on Canalicular Bile Flow in Man

1976 • 30 citations

Evidence for the existence of a carrier for bromosulphonphthalein in the liver cell plasma membrane

1974 • 23 citations

Effect of Ethynyl Estradiol on Hepatic Excretory Function of the Rat

1969 • 23 citations

Effect of ethacrynic acid on bile formation in sheep, dogs, rats, guinea pigs and rabbits.

1972 • 20 citations

Characteristics Common to Choleretic Increments of Bile Induced by Theophylline, Glucagon and SQ-20009 in the dog

1975 • 19 citations

Influence of theophylline on bile formation in the dog.

1973 • 18 citations

Choleretic effects of ouabain and ethacrynic acid in the isolated perfused rat liver

1972 • 15 citations

Bile salts and bile formation in rats, rabbits and guinea pigs

1975 • 15 citations

Experimental investigations in choleresis

1968 • 13 citations

Rapid passage of mannitol into liver and bile

1970 • 11 citations

The transport capacity for bilirubin in rat liver and its relation to bile flow

1969 • 9 citations

Independent pathways for water and solute movement across the cell membrane

1972 • 8 citations