Role of the inositol 1,4,5-trisphosphate receptor in early embryonic development

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

A molecular mechanism for the effect of lithium on development.

1996 • 2,270 citations

Differential activation of transcription factors induced by Ca2+ response amplitude and duration

1997 • 1,533 citations

Sensitivity of CaM Kinase II to the Frequency of Ca ²⁺ Oscillations

1998 • 1,263 citations

Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor

1989 • 1,132 citations

Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400

1989 • 1,039 citations

Neural and developmental actions of lithium: A unifying hypothesis

1989 • 1,005 citations

Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression

1998 • 855 citations

Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling

1997 • 671 citations

Solubilization, purification, and characterization of an inositol trisphosphate receptor.

1988 • 650 citations

Microtubules and the endoplasmic reticulum are highly interdependent structures.

1986 • 633 citations

Changes of free calcium levels with stages of the cell division cycle

1985 • 591 citations

Putative receptor for inositol 1,4,5-trisphosphate similar to ryanodine receptor

1989 • 531 citations

Block of Ca ²⁺ Wave and Ca ²⁺ Oscillation by Antibody to the Inositol 1,4,5-Trisphosphate Receptor in Fertilized Hamster Eggs

1992 • 493 citations

Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos

1995 • 492 citations

Structure and expression of the rat inositol 1,4,5-trisphosphate receptor.

1990 • 469 citations

Lithium perturbation and goosecoid expression identify a dorsal specification pathway in the pregastrula zebrafish

1993 • 458 citations

The polyphosphoinositide cycle exists in the nuclei of Swiss 3T3 cells under the control of a receptor (for IGF-I) in the plasma membrane, and stimulation of the cycle increases nuclear diacylglycerol and apparently induces translocation of protein kinase

1991 • 454 citations

Inositol 1,4,5-trisphosphate receptor localized to endoplasmic reticulum in cerebellar Purkinje neurons

1989 • 431 citations

Distinct WNT Pathways Regulating AER Formation and Dorsoventral Polarity in the Chick Limb Bud

1998 • 413 citations

Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development.

1996 • 405 citations

An elevated free cytosolic Ca2+ wave follows fertilization in eggs of the frog, Xenopus laevis.

1985 • 336 citations

Lighting the fuse at fertilization

1993 • 328 citations

Free Ca2+ increases in exponential phases during mouse oocyte activation

1981 • 322 citations

Nuclear localization and signalling activity of phosphoinositidase Cβ in Swiss 3T3 cells

1992 • 321 citations

Inositol 1,4,5-trisphosphate microinjection activates sea urchin eggs

1984 • 316 citations

Redundant Mechanisms of Calcium-Induced Calcium Release Underlying Calcium Waves During Fertilization of Sea Urchin Eggs

1993 • 313 citations

A cerebellar Purkinje cell marker P400 protein is an inositol 1,4,5-trisphosphate (InsP3) receptor protein. Purification and characterization of InsP3 receptor complex.

1990 • 280 citations

The subtypes of the mouse inositol 1,4,5-trisphosphate receptor are expressed in a tissue-specific and developmentally specific manner.

1991 • 262 citations

Inositol 1,4,5-trisphosphate-induced calcium release and guanine nucleotide-binding protein-mediated periodic calcium rises in golden hamster eggs

1988 • 256 citations

Three additional inositol 1,4,5-trisphosphate receptors: molecular cloning and differential localization in brain and peripheral tissues.

1992 • 253 citations

Meiosis, egg activation, and nuclear envelope breakdown are differentially reliant on Ca2+, whereas germinal vesicle breakdown is Ca2+ independent in the mouse oocyte

1992 • 241 citations

Organization of the sea urchin egg endoplasmic reticulum and its reorganization at fertilization.

1991 • 225 citations

The Xenopus IP3 receptor: Structure, function, and localization in oocytes and eggs

1993 • 215 citations

Regulation of Intracellular Calcium in the Mouse Egg: Calcium Release in Response to Sperm or Inositol Trisphosphate is Enhanced after Meiotic Maturation1

1994 • 213 citations

Regulation of cortical vesicle exocytosis in sea urchin eggs by inositol 1,4,5-trisphosphate and GTP-binding protein.

1986 • 209 citations

Spontaneous Activation of Ovulated Mouse Eggs: Time-dependent Effects on M-phase Exit, Cortical Granule Exocytosis, Maternal Messenger Ribonucleic Acid Recruitment, and Inositol 1,4,5-trisphosphate Sensitivity1

1997 • 195 citations

Lithium-induced teratogenesis in frog embryos prevented by a polyphosphoinositide cycle intermediate or a diacylglycerol analog

1989 • 185 citations

Continuous network of endoplasmic reticulum in cerebellar Purkinje neurons.

1994 • 182 citations

Cell-cycle calcium transients driven by cyclic changes in inositol trisphosphate levels

1994 • 180 citations

Reorganization of the Endoplasmic Reticulum during Meiotic Maturation of the Mouse Oocyte

1995 • 175 citations

Redistribution and Increase in Cortical Inositol 1,4,5-Trisphosphate Receptors after Meiotic Maturation of the Mouse Oocyte

1996 • 170 citations

Development of Inositol Trisphosphate-Induced Calcium Release Mechanism during Maturation of Hamster Oocytes

1993 • 167 citations

Free calcium wave upon activation in Xenopus eggs

1987 • 164 citations

The involvement of ankyrin in the regulation of inositol 1,4,5-trisphosphate receptor-mediated internal Ca2+ release from Ca2+ storage vesicles in mouse T-lymphoma cells.

1993 • 164 citations

Translational control of InsP3-induced chromatin condensation during the early cell cycles of sea urchin embryos

1988 • 152 citations

Developmental expression and intracellular location of P400 protein characteristic of Purkinje cells in the mouse cerebellum

1989 • 145 citations

An Anaphase Calcium Signal Controls Chromosome Disjunction in Early Sea Urchin Embryos

1998 • 142 citations

Purification and Characterization of P₄₀₀ Protein, a Glycoprotein Characteristic of Purkinje Cell, from Mouse Cerebellum

1988 • 141 citations

Development of calcium release mechanisms during starfish oocyte maturation

1990 • 140 citations

Involvement of inositol 1,4,5-trisphosphate-mediated Ca2+release in early and late events of mouse egg activation

1994 • 134 citations

Fertilization Events Induced by Neurotransmitters After Injection of mRNA in Xenopus Eggs

1988 • 129 citations

Inductive effects of fibroblast growth factor and lithium ion on Xenopus blastula ectoderm

1988 • 126 citations

Developmental Changes in the Distribution of the Endoplasmic Reticulum and Inositol 1,4,5-Trisphosphate Receptors and the Spatial Pattern of Ca2+ Release during Maturation of Hamster Oocytes

1995 • 124 citations

A localized elevation of cytosolic free calcium is associated with cytokinesis in the zebrafish embryo.

1995 • 124 citations

Slow calcium waves accompany cytokinesis in medaka fish eggs.

1991 • 119 citations

Cortical localization of a calcium release channel in sea urchin eggs.

1992 • 118 citations

Expression of Inositol 1,4,5-Trisphosphate Receptors in Mouse Oocytes and Early Embryos: The Type I Isoform Is Upregulated in Oocytes and Downregulated after Fertilization

1998 • 116 citations

Immunogold localization of inositol 1,4,5-trisphosphate (InsP3) receptor in mouse cerebellar Purkinje cells using three monoclonal antibodies.

1990 • 114 citations

Dorsalization of mesoderm induction by lithium

1989 • 109 citations

Differential Distribution of Inositol Trisphosphate Receptor Isoforms in Mouse Oocytes1

1999 • 105 citations

Role of Inositol 1,4,5-Trisphosphate Receptor in Ventral Signaling in Xenopus Embryos

1997 • 99 citations

Confocal microscopy of fertilization-induced calcium dynamics in sea urchin eggs

1992 • 98 citations

Local perinuclear calcium signals associated with mitosis-entry in early sea urchin embryos.

1996 • 93 citations

Calcium transients during early development in single starfish (Asterias forbesi) oocytes.

1984 • 86 citations

In Vitro and In Vivo Inhibition of Inositol Monophosphatase by the Bisphosphonate L‐690,330

1993 • 83 citations

Structural changes in the endoplasmic reticulum of starfish oocytes during meiotic maturation and fertilization

1994 • 83 citations

Calcium waves along the cleavage furrows in cleavage-stage Xenopus embryos and its inhibition by heparin.

1996 • 81 citations

Distribution of inositol 1,4,5‐trisphosphate receptor mRNA in mouse tissues

1990 • 80 citations

Evidence for the involvement of a pertussis toxin-insensitive G-protein in egg activation of the frog, Xenopus laevis

1991 • 78 citations

Modulation of Embryonic Intracellular Ca 2/ Signaling by Wnt-5A

1997 • 76 citations

Presence of Inositol 1,4,5-Trisphosphate Receptor, Calreticulin, and Calsequestrin in Eggs of Sea Urchins and Xenopus laevis

1994 • 74 citations

Localized Calcium Signals in Early Zebrafish Development

1995 • 71 citations

A cholera toxin-sensitive G-protein stimulates exocytosis in sea urchin eggs

1987 • 69 citations

Role of Two Series of Ca2+Oscillations in Activation of Ascidian Eggs

1998 • 69 citations

Developmental Expression of the Inositol 1,4,5-Trisphosphate Receptor and Structural Changes in the Endoplasmic Reticulum during Oogenesis and Meiotic Maturation ofXenopus laevis

1997 • 68 citations

The restrictive effect of early exposure to lithium upon body pattern in Xenopus development, studied by quantitative anatomy and immunofluorescence

1988 • 61 citations

Marked Alteration at Midblastula Transition in the Effect of Lithium on Formation of the Larval Body Pattern of Xenopus laevis

1989 • 61 citations

Modulation of Xenopus embryo mesoderm-specific gene expression and dorsoanterior patterning by receptors that activate the phosphatidylinositol cycle signal transduction pathway

1996 • 55 citations

Lithium blocks cell cycle transitions in the first cell cycles of sea urchin embryos, an effect rescued by myo-inositol

1997 • 55 citations

Inositol 1,4,5-trisphosphate-induced calcium release in the organelle layers of the stratified, intact egg of Xenopus laevis.

1990 • 52 citations

Structural Changes of the Endoplasmic Reticulum of Sea Urchin Eggs during Fertilization

1993 • 51 citations

Intracellular free calcium oscillates during cell division of Xenopus embryos.

1991 • 44 citations

Oscillation of Intracellular Free Calcium in Cleaving and Cleavage-Arrested Embryos of Xenopus laevis

1993 • 38 citations

Stepwise Transfer from High to Low Lithium Concentrations Increases the Head-Forming Potential in Hydra vulgaris and Possibly Activates the PI Cycle

1996 • 35 citations

Developmental expression of the inositol 1,4,5-trisphosphate receptor and localization of inositol 1,4,5-trisphosphate during early embryogenesis in Xenopus laevis

1997 • 31 citations

10 Regulation of the cell division cycle by inositol trisphosphate and the calcium signaling pathway

1995 • 29 citations

Roles for the phosphatidylinositol cycle in early development

1988 • 27 citations

G-proteins and egg activation

1988 • 26 citations

Effect of Lithium on Ionic Balance and Polyphosphoinositide Metabolism during Larval Vegetalization of the Sea Urchin Paracentrotus lividus

1993 • 18 citations

Exocytosis of Cortical Alveoli and Its Initiation Time in Medaka Eggs Induced by Microinjection of Various Agents

1989 • 14 citations